SARS-CoV-2 placental infection is associated with massive perivillous fibrin deposition at the maternal-fetal interface: a preliminary study"

Abstract

We observed an increased frequency of massive perivillous fibrin deposition (MPFD) ,during the second COVID-19 pandemic wave dominated by the alpha variant of SARS-CoV-2. MPFD associated with 100% RT-PCR positivity for SARS-CoV-2 and detection by immunohistochemistry. The alpha variant was identified in all placentas with MPFD that could be sequenced.