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. 2022 Mar 1;11(5):838. doi: 10.3390/cells11050838

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Profile of the activity of the immunoproteasome subunits over constitutive proteasome subunits determined by ABP labelling in different hematological malignancies. (A) Comparison between the ratio of activity of proteasome β5i versus β5c, data represent mean ± SD. (B) Comparison between the ratio of activity of proteasome β1i versus β1c, data represent mean ± SD. (C) Comparison between the ratio of activity of proteasome β2i versus β2c, data represent mean ± SD. In all analyses, statistical significance was obtained with ANOVA and Tukey’s multiple comparison test, where * represents p < 0.05, *** represents p < 0.001 and **** represents p < 0.0001. AML = acute myeloid leukemia, B-ALL = B-cell acute lymphoblastic leukemia, B-CLL = B-cell chronic lymphocytic leukemia, MM = multiple myeloma, PCL = plasma-cell leukemia, PBMC = peripheral blood mononuclear cells.