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Predicted ADMET for Jusanin and reference.
| Comp. | BBB Level a | Solubility Level | Absorption Level | CYP2D6 Prediction b | PPB Prediction c |
|---|---|---|---|---|---|
| Jusanin | V. low | good | good | non inhibitor | >90% |
| Simeprevir | V. low | low | V. poor | non inhibitor | >90% |
a BBB level, blood–brain barrier penetration level; b CYP2D6, cytochrome P2D6 inhibition; c PBB, plasma protein binding level.
