Table 6.
Comp. | FDA Rodent Carcinogenicity (Mouse-Male) |
Carcinogenic Potency TD50 (Rat) a |
Rat Maximum Tolerated Dose (Feed) b |
Rat Oral LD50 b | Rat Chronic LOAEL b | Ocular Irritancy | Skin Irritancy |
---|---|---|---|---|---|---|---|
Jusanin | Non-Carcinogen | 13.5782 | 0.3502 | 0.4621 | 0.0624 | Mild | Non-Irritant |
Simeprevir | Non-Carcinogen | 0.2803 | 0.0030 | 0.2088 | 0.0021 | Mild | Non-Irritant |
a Unit: mg/kg body weight/day b Unit: g/kg body weight.