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Total synthesis of RvD6, as reported by Rodríguez and Spur [94]. Reagents and conditions: i. Pd(PPh3)4, CuI, PrNH2, benzene, rt; ii. AgNO3, CH3OH, H2O, NaCN, 0 °C; iii. MeCOCl, CH3OH, 0 °C to rt; iv. Zn(Cu/Ag), CH3OH, H2O, 50 °C; v. 1 N LiOH, H2O, THF, 0 °C, then H+ (NaH2PO4 saturated) (yields were not provided).
