Figure 5I. miRNA-30a-5p was down-regulated in the sera of LUAD using qRT-PCR assay, at which it is a reverse of the two groups in the previous Figure 5I. Figure 8B, it seems that the labels of the X-axis being masked in the previous Figure 8B. The corrected Figure 5 and Figure 8 are shown as below.
Figure 5.
miRNA-30a-5p was down-regulated in LUAD. (A) MiRNA-30a-5p was down-regulated in lung cancer based on TCGA-LAUD dataset. (B–G) Correlation between miRNA-30a-5p and clinicpathologic features, including the pathology stage, TNM stage, smoker, and therapy outcome in LUAD. (H) ROC curve analysis of miRNA-30a-5p showed an AUC value of 0.902 in LUAD. (I) miRNA-30a-5p was down-regulated in peripheral blood serum of LUAD analysed using qRT-PCR assay. *P < 0.05, ***P < 0.001. CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease. NS: p >0.05.
Figure 8.
Over-expression of miRNA-30a-5p inhibits the cell proliferation and migration ability of LUAD cells. (A–C) The expression of miRNA-30a-5p in LUAD was examined by GEO datasets. (D) The expression of miRNA-30a-5p in LUAD cell lines was examined by qRT-PCR assay. (E, F) The expression of miRNA-30a-5p in LUAD cells lines after over-expression of miRNA-30a-5p was examined by using the qRT-PCR assay. (G–J) Over-expression of miRNA-30a-5p on cell growth ability examined by clone information and BrdU assays. (K, L) Over-expression of miRNA-30a-5p on cell migration ability examined by transwell and wound healing assay. Quantification data were also indicated. Scale bar=50 mm. ***P < 0.001.
The authors apologize for these errors and state that this does not change the original scientific conclusions of the article. The original article has been updated.
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