Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

Wouter van Rheenen; Rick A A van der Spek; Mark K Bakker; Joke J F A van Vugt; Paul J Hop; Ramona A J Zwamborn; Niek de Klein; Harm-Jan Westra; Olivier B Bakker; Patrick Deelen; Gemma Shireby; Eilis Hannon; Matthieu Moisse; Denis Baird; Restuadi Restuadi; Egor Dolzhenko; Annelot M Dekker; Klara Gawor; Henk-Jan Westeneng; Gijs H P Tazelaar; Kristel R van Eijk; Maarten Kooyman; Ross P Byrne; Mark Doherty; Mark Heverin; Ahmad Al Khleifat; Alfredo Iacoangeli; Aleksey Shatunov; Nicola Ticozzi; Johnathan Cooper-Knock; Bradley N Smith; Marta Gromicho; Siddharthan Chandran; Suvankar Pal; Karen E Morrison; Pamela J Shaw; John Hardy; Richard W Orrell; Michael Sendtner; Thomas Meyer; Nazli Başak; Anneke J van der Kooi; Antonia Ratti; Isabella Fogh; Cinzia Gellera; Giuseppe Lauria; Stefania Corti; Cristina Cereda; Daisy Sproviero; Sandra D’Alfonso; Gianni Sorarù; Gabriele Siciliano; Massimiliano Filosto; Alessandro Padovani; Adriano Chiò; Andrea Calvo; Cristina Moglia; Maura Brunetti; Antonio Canosa; Maurizio Grassano; Ettore Beghi; Elisabetta Pupillo; Giancarlo Logroscino; Beatrice Nefussy; Alma Osmanovic; Angelica Nordin; Yossef Lerner; Michal Zabari; Marc Gotkine; Robert H Baloh; Shaughn Bell; Patrick Vourc’h; Philippe Corcia; Philippe Couratier; Stéphanie Millecamps; Vincent Meininger; François Salachas; Jesus S Mora Pardina; Abdelilah Assialioui; Ricardo Rojas-García; Patrick A Dion; Jay P Ross; Albert C Ludolph; Jochen H Weishaupt; David Brenner; Axel Freischmidt; Gilbert Bensimon; Alexis Brice; Alexandra Durr; Christine A M Payan; Safa Saker-Delye; Nicholas W Wood; Simon Topp; Rosa Rademakers; Lukas Tittmann; Wolfgang Lieb; Andre Franke; Stephan Ripke; Alice Braun; Julia Kraft

doi:10.1038/s41588-022-01020-3

. 2022 Jan 31;54(3):361. doi: 10.1038/s41588-022-01020-3

Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

Wouter van Rheenen ^1,^✉,^#, Rick A A van der Spek ^1,^#, Mark K Bakker ^1,^#, Joke J F A van Vugt ¹, Paul J Hop ¹, Ramona A J Zwamborn ¹, Niek de Klein ², Harm-Jan Westra ², Olivier B Bakker ², Patrick Deelen ^2,³, Gemma Shireby ⁴, Eilis Hannon ⁴, Matthieu Moisse ^5,^6,⁷, Denis Baird ^8,⁹, Restuadi Restuadi ¹⁰, Egor Dolzhenko ¹¹, Annelot M Dekker ¹, Klara Gawor ¹, Henk-Jan Westeneng ¹, Gijs H P Tazelaar ¹, Kristel R van Eijk ¹, Maarten Kooyman ¹, Ross P Byrne ¹², Mark Doherty ¹², Mark Heverin ¹³, Ahmad Al Khleifat ¹⁴, Alfredo Iacoangeli ^14,^15,¹⁶, Aleksey Shatunov ¹⁴, Nicola Ticozzi ^17,¹⁸, Johnathan Cooper-Knock ¹⁹, Bradley N Smith ¹⁴, Marta Gromicho ²⁰, Siddharthan Chandran ^21,²², Suvankar Pal ^21,²², Karen E Morrison ²³, Pamela J Shaw ¹⁹, John Hardy ²⁴, Richard W Orrell ²⁵, Michael Sendtner ²⁶, Thomas Meyer ²⁷, Nazli Başak ²⁸, Anneke J van der Kooi ²⁹, Antonia Ratti ^17,³⁰, Isabella Fogh ¹⁴, Cinzia Gellera ³¹, Giuseppe Lauria ^32,³³, Stefania Corti ^18,³⁴, Cristina Cereda ³⁵, Daisy Sproviero ³⁵, Sandra D’Alfonso ³⁶, Gianni Sorarù ³⁷, Gabriele Siciliano ³⁸, Massimiliano Filosto ³⁹, Alessandro Padovani ³⁹, Adriano Chiò ^40,⁴¹, Andrea Calvo ^40,⁴¹, Cristina Moglia ^40,⁴¹, Maura Brunetti ⁴⁰, Antonio Canosa ^40,⁴¹, Maurizio Grassano ⁴⁰, Ettore Beghi ⁴², Elisabetta Pupillo ⁴², Giancarlo Logroscino ⁴³, Beatrice Nefussy ⁴⁴, Alma Osmanovic ^45,⁴⁶, Angelica Nordin ⁴⁷, Yossef Lerner ^48,⁴⁹, Michal Zabari ^48,⁴⁹, Marc Gotkine ^48,⁴⁹, Robert H Baloh ^50,⁵¹, Shaughn Bell ^50,⁵¹, Patrick Vourc’h ^52,⁵³, Philippe Corcia ^53,⁵⁴, Philippe Couratier ^55,⁵⁶, Stéphanie Millecamps ⁵⁷, Vincent Meininger ⁵⁸, François Salachas ^57,⁵⁹, Jesus S Mora Pardina ⁶⁰, Abdelilah Assialioui ⁶¹, Ricardo Rojas-García ⁶², Patrick A Dion ^63,⁶⁴, Jay P Ross ^63,⁶⁵, Albert C Ludolph ⁶⁶, Jochen H Weishaupt ⁶⁷, David Brenner ⁶⁷, Axel Freischmidt ^66,⁶⁸, Gilbert Bensimon ^69,^70,^71,⁷², Alexis Brice ⁷³, Alexandra Durr ⁷³, Christine A M Payan ⁶⁹, Safa Saker-Delye ⁷⁴, Nicholas W Wood ⁷⁵, Simon Topp ¹⁴, Rosa Rademakers ⁷⁶, Lukas Tittmann ⁷⁷, Wolfgang Lieb ⁷⁷, Andre Franke ⁷⁸, Stephan Ripke ^79,^80,⁸¹, Alice Braun ⁸¹, Julia Kraft ⁸¹, David C Whiteman ⁸², Catherine M Olsen ⁸², Andre G Uitterlinden ^83,⁸⁴, Albert Hofman ⁸⁴, Marcella Rietschel ^85,⁸⁶, Sven Cichon ^87,^88,^89,⁹⁰, Markus M Nöthen ^87,⁸⁸, Philippe Amouyel ⁹¹; SLALOM Consortium; PARALS Consortium; SLAGEN Consortium; SLAP Consortium, Bryan J Traynor ^92,⁹³, Andrew B Singleton ⁹⁴, Miguel Mitne Neto ⁹⁵, Ruben J Cauchi ⁹⁶, Roel A Ophoff ^97,^98,⁹⁹, Martina Wiedau-Pazos ¹⁰⁰, Catherine Lomen-Hoerth ¹⁰¹, Vivianna M van Deerlin ¹⁰², Julian Grosskreutz ^103,¹⁰⁴, Annekathrin Roediger ¹⁰³, Nayana Gaur ¹⁰³, Alexander Jörk ¹⁰³, Tabea Barthel ¹⁰³, Erik Theele ¹⁰³, Benjamin Ilse ¹⁰³, Beatrice Stubendorff ¹⁰³, Otto W Witte ¹⁰³, Robert Steinbach ¹⁰³, Christian A Hübner ¹⁰⁵, Caroline Graff ¹⁰⁶, Lev Brylev ^107,^108,¹⁰⁹, Vera Fominykh ^107,¹⁰⁹, Vera Demeshonok ¹¹⁰, Anastasia Ataulina ¹⁰⁷, Boris Rogelj ^111,^112,¹¹³, Blaž Koritnik ¹¹⁴, Janez Zidar ¹¹⁴, Metka Ravnik-Glavač ¹¹⁵, Damjan Glavač ¹¹⁶, Zorica Stević ¹¹⁷, Vivian Drory ^44,¹¹⁸, Monica Povedano ⁶¹, Ian P Blair ¹¹⁹, Matthew C Kiernan ¹²⁰, Beben Benyamin ^10,¹²¹, Robert D Henderson ^122,¹²³, Sarah Furlong ¹¹⁹, Susan Mathers ¹²⁴, Pamela A McCombe ^123,¹²⁵, Merrilee Needham ^126,^127,¹²⁸, Shyuan T Ngo ^122,^123,¹²⁵, Garth A Nicholson ^119,^129,¹³⁰, Roger Pamphlett ¹³¹, Dominic B Rowe ¹¹⁹, Frederik J Steyn ^123,¹³², Kelly L Williams ¹¹⁹, Karen A Mather ^133,¹³⁴, Perminder S Sachdev ^133,¹³⁵, Anjali K Henders ¹⁰, Leanne Wallace ¹⁰, Mamede de Carvalho ²⁰, Susana Pinto ²⁰, Susanne Petri ⁴⁵, Markus Weber ¹³⁶, Guy A Rouleau ^63,^64,⁶⁵, Vincenzo Silani ^17,¹⁸, Charles J Curtis ^137,¹³⁸, Gerome Breen ^137,¹³⁸, Jonathan D Glass ¹³⁹, Robert H Brown Jr ¹⁴⁰, John E Landers ¹⁴⁰, Christopher E Shaw ¹⁴, Peter M Andersen ⁴⁷, Ewout J N Groen ¹, Michael A van Es ¹, R Jeroen Pasterkamp ¹⁴¹, Dongsheng Fan ¹⁴², Fleur C Garton ¹⁰, Allan F McRae ¹⁰, George Davey Smith ^9,¹⁴³, Tom R Gaunt ^9,¹⁴³, Michael A Eberle ¹¹, Jonathan Mill ⁴, Russell L McLaughlin ¹², Orla Hardiman ¹³, Kevin P Kenna ^1,¹⁴¹, Naomi R Wray ^10,¹²⁵, Ellen Tsai ⁸, Heiko Runz ⁸, Lude Franke ², Ammar Al-Chalabi ^14,¹⁴⁴, Philip Van Damme ^5,^6,⁷, Leonard H van den Berg ¹, Jan H Veldink ^1,^✉

¹Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands

²Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands

³Department of Genetics, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands

⁴University of Exeter Medical School, College of Medicine and Health, University of Exeter, Exeter, UK

⁵Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), KU Leuven—University of Leuven, Leuven, Belgium

⁶Laboratory of Neurobiology, VIB, Center for Brain & Disease Research, Leuven, Belgium

⁷Department of Neurology, University Hospitals Leuven, Leuven, Belgium

⁸Translational Biology, Biogen, Boston, MA USA

⁹MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, University of Bristol, Bristol, UK

¹⁰Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland Australia

¹¹Illumina, San Diego, CA USA

¹²Complex Trait Genomics Laboratory, Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland

¹³Academic Unit of Neurology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland

¹⁴Maurice Wohl Clinical Neuroscience Institute, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK

¹⁵Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK

¹⁶National Institute for Health Research Biomedical Research Centre and Dementia Unit, South London and Maudsley NHS Foundation Trust and King’s College London, London, UK

¹⁷Department of Neurology, Stroke Unit and Laboratory of Neuroscience, Istituto Auxologico Italiano IRCCS, Milan, Italy

¹⁸Department of Pathophysiology and Transplantation, ‘Dino Ferrari’ Center, Università degli Studi di Milano, Milan, Italy

¹⁹Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, UK

²⁰Instituto de Fisiologia, Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal

²¹Euan MacDonald Centre for Motor Neurone Disease Research, Edinburgh, UK

²²UK Dementia Research Institute, University of Edinburgh, Edinburgh, UK

²³School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, Belfast, UK

²⁴Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK

²⁵Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, London, UK

²⁶Institute of Clinical Neurobiology, University Hospital Würzburg, Würzburg, Germany

²⁷Charité University Hospital, Humboldt University, Berlin, Germany

²⁸Koç University, School of Medicine, KUTTAM-NDAL, Istanbul, Turkey

²⁹Department of Neurology, Academic Medical Center, Amsterdam, the Netherlands

³⁰Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milan, Italy

³¹Unit of Medical Genetics and Neurogenetics, Fondazione IRCCS Istituto Neurologico ‘Carlo Besta’, Milan, Italy

³²3rd Neurology Unit, Motor Neuron Diseases Center, Fondazione IRCCS Istituto Neurologico ‘Carlo Besta’, MIlan, Italy

³³Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy

³⁴Neurology Unit, IRCCS Foundation Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy

³⁵Genomic and Post-Genomic Center, IRCCS Mondino Foundation, Pavia, Italy

³⁶Department of Health Sciences, University of Eastern Piedmont, Novara, Italy

³⁷Department of Neurosciences, University of Padova, Padova, Italy

³⁸Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

³⁹Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy

⁴⁰’Rita Levi Montalcini’ Department of Neuroscience, ALS Centre, University of Torino, Turin, Italy

⁴¹Neurologia 1, Azienda Ospedaliero Universitaria Città della Salute e della Scienza, Turin, Italy

⁴²Laboratory of Neurological Diseases, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy

⁴³Department of Clinical Research in Neurology, University of Bari at ‘Pia Fondazione Card G. Panico’ Hospital, Bari, Italy

⁴⁴Neuromuscular Diseases Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel

⁴⁵Department of Neurology, Hannover Medical School, Hannover, Germany

⁴⁶Essener Zentrum für Seltene Erkrankungen (EZSE), University Hospital Essen, Essen, Germany

⁴⁷Department of Clinical Sciences, Neurosciences, Umeå University, Umeå, Sweden

⁴⁸Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel

⁴⁹Department of Neurology, the Agnes Ginges Center for Human Neurogenetics, Hadassah Medical Center, Jerusalem, Israel

⁵⁰Center for Neural Science and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA USA

⁵¹Department of Neurology, Neuromuscular Division, Cedars-Sinai Medical Center, Los Angeles, CA USA

⁵²Service de Biochimie et Biologie Moléculaire, CHU de Tours, Tours, France

⁵³UMR 1253, Université de Tours, Inserm, Tours, France

⁵⁴Centre de référence sur la SLA, CHU de Tours, Tours, France

⁵⁵Centre de référence sur la SLA, CHRU de Limoges, Limoges, France

⁵⁶UMR 1094, Université de Limoges, Inserm, Limoges, France

⁵⁷ICM, Institut du Cerveau, Inserm, CNRS, Sorbonne Université, Hôpital Pitié-Salpêtrière, Paris, France

⁵⁸Hôpital des Peupliers, Ramsay Générale de Santé, Paris, France

⁵⁹Département de Neurologie, Centre de référence SLA Ile de France, Hôpital de la Pitié-Salpêtrière, AP-HP, Paris, France

⁶⁰ALS Unit, Hospital San Rafael, Madrid, Spain

⁶¹Functional Unit of Amyotrophic Lateral Sclerosis (UFELA), Service of Neurology, Bellvitge University Hospital, L’Hospitalet de Llobregat, Barcelona, Spain

⁶²MND Clinic, Neurology Department, Hospital de la Santa Creu i Sant Pau de Barcelona, Universitat Autonoma de Barcelona, Barcelona, Spain

⁶³Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec Canada

⁶⁴Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec Canada

⁶⁵Department of Human Genetics, McGill University, Montreal, Quebec Canada

⁶⁶Department of Neurology, Ulm University, Ulm, Germany

⁶⁷Division of Neurodegeneration, Department of Neurology, University Medicine Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany

⁶⁸German Center for Neurodegenerative Diseases (DZNE) Ulm, Ulm, Germany

⁶⁹Département de Pharmacologie Clinique, Hôpital de la Pitié-Salpêtrière, UPMC Pharmacologie, AP-HP, Paris, France

⁷⁰Pharmacologie Sorbonne Université, Paris, France

⁷¹Institut du Cerveau, Paris Brain Institute ICM, Paris, France

⁷²Laboratoire de Biostatistique, Epidémiologie Clinique, Santé Publique Innovation et Méthodologie (BESPIM), CHU-Nîmes, Nîmes, France

⁷³Sorbonne Université, Paris Brain Institute, APHP, INSERM, CNRS, Hôpital de la Pitié Salpêtrière, Paris, France

⁷⁴Genethon, CNRS UMR, Evry, France

⁷⁵Department of Clinical and Movement Neuroscience, UCL Institute of Neurology, Queen Square, London, UK

⁷⁶Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, FL USA

⁷⁷Popgen Biobank and Institute of Epidemiology, Christian Albrechts-University Kiel, Kiel, Germany

⁷⁸Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany

⁷⁹Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA USA

⁸⁰Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA USA

⁸¹Department of Psychiatry and Psychotherapy, Charité—Universitätsmedizin, Berlin, Germany

⁸²Cancer Control Group, QIMR Berghofer Medical Research Institute, Herston, Queensland Australia

⁸³Department of Internal Medicine, Genetics Laboratory, Erasmus Medical Center Rotterdam, Rotterdam, the Netherlands

⁸⁴Department of Epidemiology, Erasmus Medical Center Rotterdam, Rotterdam, the Netherlands

⁸⁵Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany

⁸⁶Central Institute of Mental Health, Mannheim, Germany

⁸⁷Institute of Human Genetics, University of Bonn, Bonn, Germany

⁸⁸Department of Genomics, Life and Brain Center, Bonn, Germany

⁸⁹Division of Medical Genetics, University Hospital Basel and Department of Biomedicine, University of Basel, Basel, Switzerland

⁹⁰Institute of Neuroscience and Medicine INM-1, Research Center Juelich, Juelich, Germany

⁹¹INSERM UMR1167—RID-AGE LabEx DISTALZ—Risk Factors and Molecular Determinants of Aging-Related Diseases, University of Lille, Centre Hospitalier of the University of Lille, Institut Pasteur de Lille, Lille, France

⁹²Neuromuscular Diseases Research Section, Laboratory of Neurogenetics, National Institute on Aging, NIH, Porter Neuroscience Research Center, Bethesda, MD USA

⁹³Department of Neurology, Johns Hopkins University, Baltimore, MD USA

⁹⁴Molecular Genetics Section, Laboratory of Neurogenetics, National Institute on Aging, NIH, Porter Neuroscience Research Center, Bethesda, MD USA

⁹⁵Universidade de São Paulo, São Paulo, Brazil

⁹⁶Centre for Molecular Medicine and Biobanking and Department of Physiology and Biochemistry, Faculty of Medicine and Surgery, University of Malta, Msida, Malta

⁹⁷University Medical Center Utrecht, Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, Utrecht, the Netherlands

⁹⁸Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA USA

⁹⁹Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA USA

¹⁰⁰Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA USA

¹⁰¹Department of Neurology, University of California, San Francisco, CA USA

¹⁰²Center for Neurodegenerative Disease Research, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA USA

¹⁰³Hans Berger Department of Neurology, Jena University Hospital, Jena, Germany

¹⁰⁴Precision Neurology Unit, Department of Neurology, University Hospital Schleswig-Holstein, University of Luebeck, Luebeck, Germany

¹⁰⁵Institute of Human Genetics, Jena University Hospital, Jena, Germany

¹⁰⁶Department of Geriatric Medicine, Karolinska University Hospital Huddinge, Stockholm, Sweden

¹⁰⁷Department of Neurology, Bujanov Moscow Clinical Hospital, Moscow, Russia

¹⁰⁸Moscow Research and Clinical Center for Neuropsychiatry of the Healthcare Department, Moscow, Russia

¹⁰⁹Department of Functional Biochemistry of the Nervous System, Institute of Higher Nervous Activity and Neurophysiology Russian Academy of Sciences, Moscow, Russia

¹¹⁰ALS-Care Center, ‘GAOORDI’, Medical Clinic of the St. Petersburg, St. Petersburg, Russia

¹¹¹Department of Biotechnology, Jožef Stefan Institute, Ljubljana, Slovenia

¹¹²Biomedical Research Institute BRIS, Ljubljana, Slovenia

¹¹³Faculty of Chemistry and Chemical Technology, University of Ljubljana, Ljubljana, Slovenia

¹¹⁴Ljubljana ALS Centre, Institute of Clinical Neurophysiology, University Medical Centre Ljubljana, Ljubljana, Slovenia

¹¹⁵Institute of Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia

¹¹⁶Department of Molecular Genetics, Institute of Pathology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia

¹¹⁷Clinic of Neurology, Clinical Center of Serbia, School of Medicine, University of Belgrade, Belgrade, Serbia

¹¹⁸Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

¹¹⁹Centre for Motor Neuron Disease Research, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, New South Wales Australia

¹²⁰Brain and Mind Centre, University of Sydney, Sydney, New South Wales Australia

¹²¹Australian Centre for Precision Health and Allied Health and Human Performance, University of South Australia, Adelaide, South Australia Australia

¹²²Centre for Clinical Research, Australian Institute for Bioengineering and Nanotechnology, University of Queensland, Brisbane, Queensland Australia

¹²³Department of Neurology, Royal Brisbane and Women’s Hospital, Brisbane, Queensland Australia

¹²⁴Calvary Health Care Bethlehem, Parkdale, Victoria Australia

¹²⁵Queensland Brain Institute, University of Queensland, Brisbane, Queensland Australia

¹²⁶Fiona Stanley Hospital, Perth, Western Australia Australia

¹²⁷Notre Dame University, Fremantle, Western Australia Australia

¹²⁸Centre for Molecular Medicine and Innovative Therapeutics, Health Futures Institute, Murdoch University, Perth, Western Australia Australia

¹²⁹Northcott Neuroscience Laboratory, ANZAC Research Institute, Concord, New South Wales Australia

¹³⁰Molecular Medicine Laboratory, Concord Repatriation General Hospital, Concord, New South Wales Australia

¹³¹Discipline of Pathology and Department of Neuropathology, Brain and Mind Centre, University of Sydney, Sydney, New South Wales Australia

¹³²The School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, Queensland Australia

¹³³Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, New South Wales Australia

¹³⁴Neuroscience Research Australia Institute, Randwick, New South Wales Australia

¹³⁵Neuropsychiatric Institute, the Prince of Wales Hospital, UNSW, Randwick, New South Wales Australia

¹³⁶Neuromuscular Diseases Unit/ALS Clinic, Kantonsspital St. Gallen, St. Gallen, Switzerland

¹³⁷Social Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King’s College London, London, UK

¹³⁸NIHR BioResource Centre Maudsley, NIHR Maudsley Biomedical Research Centre (BRC) at South London and Maudsley NHS Foundation Trust (SLaM) & Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King’s College London, London, UK

¹³⁹Department Neurology, Emory University School of Medicine, Atlanta, GA USA

¹⁴⁰Department of Neurology, University of Massachusetts Medical School, Worcester, MA USA

¹⁴¹Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands

¹⁴²Department of Neurology, Third Hospital, Peking University, Beijing, China

¹⁴³Population Health Science, Bristol Medical School, Bristol, UK

¹⁴⁴King’s College Hospital, London, UK

¹⁴⁵IRCCS San Raffaele Hospital, Milan, Italy

¹⁴⁶Vita Salute San Raffaele University, Milan, Italy

¹⁴⁷Casa di Cura del Policlinico, Milan, Italy

¹⁴⁸NEMO Clinical Center, Serena Onlus Foundation, Niguarda Ca’ Granda Hospital, Milan, Italy

¹⁴⁹Civil Hospital of Brescia, Brescia, Italy

¹⁵⁰Neurology Unit, ASST Valcamonica, Esine, Brescia Italy

¹⁵¹Ospedale Valduce, Como, Italy

¹⁵²AO Ospedale Civile di Legnano, Legnano, Italy

¹⁵³IRCCS Istituto Neurologico Nazionale ‘C. Mondino’, Pavia, Italy

¹⁵⁴AO ‘San Gerardo’ di Monza and University of Milano-Bicocca, Milano-Bicocca, Italy

¹⁵⁵AO ‘Ospedale di Circolo Fondazione Macchi’ di Varese, Varese, Italy

¹⁵⁶Neurology Unit 1U, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy

¹⁵⁷Department of Medical Genetics, Azienda Ospedaliero Universitaria Città della Salute e della Scienza, Turin, Italy

¹⁵⁸Neurologia 3, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy

¹⁵⁹Istituto Auxologico Italiano, IRCCS, Piancavallo, Italy

¹⁶⁰Department of Neurology, ‘Amedeo Avogadro’ University of Piemonte Orientale, Novara, Italy

¹⁶¹Azienda Ospedaliero Universitaria ‘Maggiore della Carità’, Novara, Italy

¹⁶²Department of Health Sciences, ‘Amedeo Avogadro’ University of Piemonte Orientale, Novara, Italy

¹⁶³Department of Neurology and Multiple Sclerosis Center, Azienda Ospedaliero Universitaria San Luigi, Orbassano, Italy

¹⁶⁴Department of Neurology, Azienda Ospedaliera ‘Ordine Mauriziano’ di Torino, Turin, Italy

¹⁶⁵Department of Neurology, Ospedale Martini, ASL Città di Torino, Turin, Italy

¹⁶⁶Department of Neurology, Ospedale Maria Vittoria, ASL Città di Torino, Turin, Italy

¹⁶⁷Department of Neurology, Ospedale San Giovanni Bosco, ASL Città di Torino, Turin, Italy

¹⁶⁸Ospedale Humanitas Gradenigo, Turin, Italy

¹⁶⁹Department of Neurology, Ospedale ‘Santa Croce’ di Moncalieri, ASL Torino 5, Moncaliari, Italy

¹⁷⁰Department of Neurology, Ospedale Civile di Ivrea, ASL Torino 4, Ivrea, Italy

¹⁷¹Department of Neurology, Presidio Ospedaliero di Ciriè, ASL Torino 4, Ciriè, Italy

¹⁷²Department of Neurology, Ospedale ‘Degli Infermi’ di Biella, ASL Biella, Ponderano, Italy

¹⁷³Department of Neurology, Ospedale ‘Sant’Andrea’ di Vercelli, ASL Vercelli, Vercelli, Italy

¹⁷⁴Department of Clinical and Experimental Medicine, ‘Amedeo Avogadro’ University of Piemonte Orientale, Novara, Italy

¹⁷⁵Department of Neurology, Ospedale Civile ‘Edoardo Agnelli’ di Pinerolo, ALS Torino 2, Pinerolo, Italy

¹⁷⁶Department of Neurology, Azienda Ospedaliera ‘Santi Antonio e Biagio’ di Alesssandria, Alessandria, Italy

¹⁷⁷Department of Neurology, Ospedale ‘Santo Spirito’ di Casale Monferrato, ASL Alessandria, Casale Monferrato, Italy

¹⁷⁸Department of Neurology, Ospedale ‘San Giacomo’ di Novi Ligure, ASL Alesssandria, Novi Ligure, Italy

¹⁷⁹Department of Neurology, Ospedale ‘Cardinal Massia’ di Asti, ASL Asti, Asti, Italy

¹⁸⁰Department of Neurology, Azienda Ospedaliera ‘Santa Croce e Carle’ di Cuneo, Cuneo, Italy

¹⁸¹Department of Neurology, Ospedale ‘Maggiore Santissima Annuziata’ di Savigliano, ASL Cuneo 1, Savigliano, Italy

¹⁸²Department of Anesthesiology, Ospedale ‘Maggiore Santissima Annuziata’ di Savigliano, ASL Cuneo 1, Savigliano, Italy

¹⁸³Department of Neurology, Ospedale ‘Michele e Pietro Ferrero’ di Verduno, ASL Cuneo 2, Verduno, Italy

¹⁸⁴Department of Neurology, Ospedale ‘Regina Montis Regalis’ di Mondovì, ASL Cuneo 1, Aosta, Italy

¹⁸⁵Department of Neurology, Ospedale Regionale ‘Umberto Parini’ di Aosta, Aosta, Italy

¹⁸⁶Unit of General Neurology, IRCCS Mondino Foundation, Pavia, Italy

¹⁸⁷Department of Brain and Behavioural Sciences, University of Pavia, Pavia, Italy

¹⁸⁸ALS Center, Department of Neurology, Azienda Ospedaliero Universitaria Maggiore della Carità, Novara, Italy

¹⁸⁹Rare Neuromuscular Diseases Centre, Department of Human Neuroscience, Sapienza University, Rome, Italy

¹⁹⁰Unit of Medical Genetics, Department of Medical Science, University of Ferrara, Ferrara, Italy

¹⁹¹Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari, Bari, Italy

¹⁹²Neurological Department, Antonio Perrino’s Hospital, Brindisi, Italy

¹⁹³National Institute of Digestive Diseases, IRCCS S. de Bellis Research Hospital, Castellana Grotte, Italy

¹⁹⁴ASL Bari, San Paolo Hospital, Bari, Italy

¹⁹⁵Department of Neuroscience, United Hospital of Foggia, Foggia, Italy

¹⁹⁶Unit of Neurology, Department of Emergency and Critical Care, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy

¹⁹⁷Neurology Unit, Miulli Hospital, Acquaviva delle Fonti, Italy

¹⁹⁸Unit of Neurology, ‘S. Giacomo’ Hospital, Bari, Italy

¹⁹⁹Department of Neurology, ASL (Local Health Authority) at the ‘V Fazzi’ Hospital, Lecce, Italy

²⁰⁰Department of Neurology, ASL (Local Health Authority) at the ‘SS Annunziata’ Hospital, Taranto, Italy

^✉

Corresponding author.

^#

Contributed equally.

PMCID: PMC8920884 PMID: 35102318

Correction to: Nature Genetics 10.1038/s41588-021-00973-1, published online 6 December 2021.

In the version of this article initially published, the affiliation for Nazli Başak appeared incorrectly. Nazli Başak is at Koç University, School of Medicine, KUTTAM-NDAL, Istanbul, Turkey, and not Bogazici University. The error has been corrected in the HTML and PDF versions of the article.

Contributor Information

Wouter van Rheenen, Email: w.vanrheenen-2@umcutrecht.nl.

Jan H. Veldink, Email: j.h.veldink@umcutrecht.nl

SLALOM Consortium:

Giancarlo Comi, Nilo Riva, Christian Lunetta, Francesca Gerardi, Maria Sofia Cotelli, Fabrizio Rinaldi, Luca Chiveri, Maria Cristina Guaita, Patrizia Perrone, Mauro Ceroni, Luca Diamanti, Carlo Ferrarese, Lucio Tremolizzo, Maria Luisa Delodovici, and Giorgio Bono

PARALS Consortium:

Antonio Canosa, Umberto Manera, Rosario Vasta, Alessandro Bombaci, Federico Casale, Giuseppe Fuda, Paolina Salamone, Barbara Iazzolino, Laura Peotta, Paolo Cugnasco, Giovanni De Marco, Maria Claudia Torrieri, Francesca Palumbo, Salvatore Gallone, Marco Barberis, Luca Sbaiz, Salvatore Gentile, Alessandro Mauro, Letizia Mazzini, Fabiola De Marchi, Lucia Corrado, Sandra D’Alfonso, Antonio Bertolotto, Maurizio Gionco, Daniela Leotta, Enrico Odddenino, Daniele Imperiale, Roberto Cavallo, Pietro Pignatta, Marco De Mattei, Claudio Geda, Diego Maria Papurello, Graziano Gusmaroli, Cristoforo Comi, Carmelo Labate, Luigi Ruiz, Delfina Ferrandi, Eugenia Rota, Marco Aguggia, Nicoletta Di Vito, Piero Meineri, Paolo Ghiglione, Nicola Launaro, Michele Dotta, Alessia Di Sapio, and Guido Giardini

SLAGEN Consortium:

Cinzia Tiloca, Silvia Peverelli, Franco Taroni, Viviana Pensato, Barbara Castellotti, Giacomo P. Comi, Roberto Del Bo, Mauro Ceroni, Stella Gagliardi, Lucia Corrado, Letizia Mazzini, Flavia Raggi, Costanza Simoncini, Annalisa Lo Gerfo, Maurizio Inghilleri, and Alessandra Ferlini

SLAP Consortium:

Isabella L. Simone, Bruno Passarella, Vito Guerra, Stefano Zoccolella, Cecilia Nozzoli, Ciro Mundi, Maurizio Leone, Michele Zarrelli, Filippo Tamma, Francesco Valluzzi, Gianluigi Calabrese, Giovanni Boero, and Augusto Rini

PERMALINK

Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

Wouter van Rheenen

Rick A A van der Spek

Mark K Bakker

Joke J F A van Vugt

Paul J Hop

Ramona A J Zwamborn

Niek de Klein

Harm-Jan Westra

Olivier B Bakker

Patrick Deelen

Gemma Shireby

Eilis Hannon

Matthieu Moisse

Denis Baird

Restuadi Restuadi

Egor Dolzhenko

Annelot M Dekker

Klara Gawor

Henk-Jan Westeneng

Gijs H P Tazelaar

Kristel R van Eijk

Maarten Kooyman

Ross P Byrne

Mark Doherty

Mark Heverin

Ahmad Al Khleifat

Alfredo Iacoangeli

Aleksey Shatunov

Nicola Ticozzi

Johnathan Cooper-Knock

Bradley N Smith

Marta Gromicho

Siddharthan Chandran

Suvankar Pal

Karen E Morrison

Pamela J Shaw

John Hardy

Richard W Orrell

Michael Sendtner

Thomas Meyer

Nazli Başak

Anneke J van der Kooi

Antonia Ratti

Isabella Fogh

Cinzia Gellera

Giuseppe Lauria

Stefania Corti

Cristina Cereda

Daisy Sproviero

Sandra D’Alfonso

Gianni Sorarù

Gabriele Siciliano

Massimiliano Filosto

Alessandro Padovani

Adriano Chiò

Andrea Calvo

Cristina Moglia

Maura Brunetti

Antonio Canosa

Maurizio Grassano

Ettore Beghi

Elisabetta Pupillo

Giancarlo Logroscino

Beatrice Nefussy

Alma Osmanovic

Angelica Nordin

Yossef Lerner

Michal Zabari

Marc Gotkine

Robert H Baloh

Shaughn Bell

Patrick Vourc’h

Philippe Corcia

Philippe Couratier

Stéphanie Millecamps

Vincent Meininger

François Salachas

Jesus S Mora Pardina