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. 2022 Mar 15;2022:8426183. doi: 10.1155/2022/8426183

Retracted: Exploring Drug Targets in Isoprenoid Biosynthetic Pathway for Plasmodium falciparum

Biochemistry Research International 1,
PMCID: PMC8941564  PMID: 35340427

Biochemistry Research International has retracted the article titled “Exploring Drug Targets in Isoprenoid Biosynthetic Pathway for Plasmodium falciparum” [1]. The article was found to contain a substantial amount of material from previously published articles [26], including the following sources:

  1. Baichen Zhang, Kristin M. Watts, Dana Hodge, Lisa M. Kemp, David A. Hunstad, Leslie M. Hicks, Audrey R. Odom. “A Second Target of the Antimalarial and Antibacterial Agent Fosmidomycin Revealed by Cellular Metabolic Profiling”, Biochemistry, 2011. https://doi.org/10.1021/bi200113y. (Cited as reference 3)

  2. Cyrille Y. Botté, Faustine Dubar, Geoffrey I. McFadden, Eric Maréchal, Christophe Biot. “Plasmodium falciparum Apicoplast Drugs: Targets or Off-Targets?”, Chemical Reviews, 2011. https://doi.org/10.1021/cr200258w. (Not cited)

  3. J. Kipchirchir Bitok, Caren Freel Meyers. “2-Methyl- -erythritol 4-Phosphate Enhances and Sustains Cyclodiphosphate Synthase IspF Activity”, ACS Chemical Biology, 2012. https://doi.org/10.1021/cb300243w. (Not cited)

  4. Fabiana Morandi Jordão, Emília Akemi Kimura, Alejandro Miguel Katzin. “Isoprenoid biosynthesis in the erythrocytic stages of Plasmodium falciparum”, Memórias do Instituto Oswaldo Cruz, 2011. https://doi.org/10.1590/S0074-02762011000900018. (Cited as reference 6)

  5. Lisheng Deng, Jiasheng Diao, Pinhong Chen, Venugopal Pujari et al. “Inhibition of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase by Lipophilic Phosphonates: SAR, QSAR, and Crystallographic Studies”, Journal of Medicinal Chemistry, 2011. https://doi.org/10.1021/jm200363d. (Not cited)

The authors disagree with this retraction.

References

  • 1.Qidwai T., Jamal F., Khan M. Y., Sharma B. Exploring Drug Targets in Isoprenoid Biosynthetic Pathway for Plasmodium falciparum. Biochemistry Research International . 2014;2014:12. doi: 10.1155/2014/657189.657189 [DOI] [PMC free article] [PubMed] [Google Scholar] [Retracted]
  • 2.Zhang B., Watts K. M., Hodge D., et al. A second target of the antimalarial and antibacterial agent Fosmidomycin revealed by cellular metabolic profiling. Biochemistry . 2011;50 doi: 10.1021/bi200113y. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3.Botté C. Y., Dubar F., McFadden G. I., Maréchal E., Biot C. Plasmodium falciparum Apicoplast Drugs: Targets or off-targets? Chemical Reviews . 2011 doi: 10.1021/cr200258w. [DOI] [PubMed] [Google Scholar]
  • 4.Kipchirchir Bitok J., Myers C. F. 2 -methyl- -erythritol 4-phosphate Enhances and Sustains cyclodiphosphate Synthase IspF activity. ACS Chemical Biology . 2012 doi: 10.1021/cb300243w. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 5.Jordão F. M., Kimura E. A., Miguel Katzin A. Isoprenoid biosynthesis in the erythrocytic stages of Plasmodium falciparum. Memórias do Instituto Oswaldo Cruz . 2011;106 doi: 10.1590/S0074-02762011000900018. [DOI] [PubMed] [Google Scholar]
  • 6.Deng L., Diao J., Chen P., Pujari V. Inhibition of 1-deoxy-D-Xylulose-5-Phosphate Reductoisomerase by lipophilic Phosphonates: SAR, QSAR, and crystallographic Studies. Journal of Medicinal Chemistry . 2011 doi: 10.1021/jm200363d. [DOI] [PMC free article] [PubMed] [Google Scholar]

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