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. 2022 Mar 9;27(6):1787. doi: 10.3390/molecules27061787

Table 1.

Antioxidant activity of Asparagopsis extracts.

Species Experimental Assay Extract Result Units Ref.
A. armata DPPH Dichloromethane-mehtanol 1:1 6.25 EC50 mg/mL [77]
BHA (positive control) 0.04 EC50 mg/mL [77]
BHT (positive control) 0.06 EC50 mg/mL [77]
Ascorbic acid (positive control) 0.06 EC50 mg/mL [77]
α-tocopherol (positive control) 0.014 EC50 mg/mL [77]
Methanol 0.86 EC50 mg/mL [78]
BHA (positive control) 0.008 EC50 mg/mL [78]
BHT (positive control) 0.011 EC50 mg/mL [78]
Methanol 23.9 ± 0.3 % radical-scavenging activity at 10 mg/mL [79]
Nitric oxide Ethanol 14.33 EC25 mg dry algae/mL [80]
Deoxyribose test Water 68.76 % inhibition at 1 mg/mL [78]
A. taxiformis Hydrogen-peroxide scavenging Chloroform 11.07 ± 0.151 % inhibition at 500 µg/mL [81]
Petroleum ether 10.88 ± 0.139 % inhibition at 500 µg/mL [81]
Methanol 10.77 ± 0.131 % inhibition at 500 µg/mL [81]
Ethyl acetate 10.25 ± 0.136 % inhibition at 500 µg/mL [81]
Ascorbic acid (positive control) 17.59 ± 0.222 % inhibition at 500 µg/mL [81]
Superoxide-radical scavenging Methanol 85.00 ± 0.002 % scavenging activity at 500 µg/mL [81]
Chloroform 79.21 ± 0.006 % scavenging activity at 500 µg/mL [81]
Petroleum ether 47.00 ± 0.018 % scavenging activity at 500 µg/mL [81]
Ethyl acetate 45.00 ± 0.008 % scavenging activity at 500 µg/mL [81]
Ascorbic acid (positive control) 87.11 ± 0.0005 % scavenging activity at 500 µg/mL [81]
FRAP (ferric-reducing antioxidant power) Chloroform 67.19 ± 0.0005 % antioxidant activity at 500 µg/mL [81]
Methanol 65.63 ± 0.001 % antioxidant activity at 500 µg/mL [81]
Petroleum ether 64.06 ± 0.0005 % antioxidant activity at 500 µg/mL [81]
Ethyl acetate 54.69 ± 0.0005 % antioxidant activity at 500 µg/mL [81]
Ascorbic acid (positive control) 73.44 ± 0.002 % antioxidant activity at 500 µg/mL [81]
Reducing activity Water (M1) 233.15 ± 5.15 mg AAE/100 g dw a [82]
Water (M2) 174.38 ± 11.65 mg AAE/100 g dw [82]
Ethanol (M1) 1908.44 ± 59.15 mg AAE/100 g dw [82]
Ethanol (M2) 1156.86 ± 13.87 mg AAE/100 g dw [82]
Methanol (M1) 584.46 ± 15.36 mg AAE/100 g dw [82]
Methanol (M2) 1161.47 ± 14.43 mg AAE/100 g dw [82]
Ethyl acetate (M1) 409.60 ± 10.84 mg AAE/100 g dw [82]
Ethyl acetate (M2) 707.42 ± 98.78 mg AAE/100 g dw [82]
DPPH Water (M1) 4.65 ± 0.29 IC50 mg/mL [82]
Water (M2) 1.37 ± 0.03 IC50 mg/mL [82]
Ethanol (M1) 1.54 ± 0.07 IC50 mg/mL [82]
Ethanol (M2) 1.37 ± 0.04 IC50 mg/mL [82]
Methanol (M1) 2.69 ± 0.03 IC50 mg/mL [82]
Methanol (M2) 1.64 ± 0.01 IC50 mg/mL [82]
Ethyl acetate (M1) 3.62 ± 0.04 IC50 mg/mL [82]
Ethyl acetate (M2) 1.44 ± 0.08 IC50 mg/mL [82]
Ferrous-ion chelation Water (M1) 113.01 ± 10.62 IC50 mg/mL [82]
Water (M2) 74.00 ± 1.81 IC50 mg/mL [82]
Ethanol (M1) 5.26 ± 0.27 IC50 mg/mL [82]
Ethanol (M2) 10.49 ± 0.44 IC50 mg/mL [82]
Methanol (M1) 8.36 ± 0.29 IC50 mg/mL [82]
Methanol (M2) 10.07 ± 0.18 IC50 mg/mL [82]
Ethyl acetate (M1) 1.57 ± 0.03 IC50 mg/mL [82]
Ethyl acetate (M2) 5.88 ± 0.26 IC50 mg/mL [76]

M1—Extraction by sonication + stirring; M2—Sohxlet extraction; a mg l-ascorbic acid equivalent per 100 g of dry weight.