Table 5.
Enzyme inhibition data for inhibitors of PDCoV Mpro.
| Compound | Structure | Ki (µM) | k3 (10−3s−1) | k3/Ki |
|---|---|---|---|---|
| N3 |
|
11.98 ± 0.13 | 72.9 ± 7.1 | 6.1 |
| M14 |
|
7.56 ± 0.26 | 104.4 ± 2.3 | 13.8 |
| M25 |
|
8.80 ± 0.15 | 86.8 ± 5.1 | 9.9 |
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