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. 2022 Mar 16;10(3):629. doi: 10.3390/microorganisms10030629

Table 5.

Impact of PFA on proliferation of IPEC-J2 cells.

Stimulant/Incubation Time Substance Main Results Reference
- Perilla frutascens extracts (0.4 mg/400 µL medium):
1. Extracted with water
2. Extracted with 50% ethanol
3. Extracted with 100% EtOH
4. Extracted with 90% methanol (0.5% formic acid)
Cell proliferation ↓
67 kDa laminin receptor and cyclin D1 expression (cancer related genes) ↓
[95]
H2O2 (4 h) (Cell Cycle)
POST (3 h)
Quercetin (1.25–5 µg/mL) G0/G1 phase ↓, S Phase ↑, proliferation index ↑, P 21 and P 27 ↓
Epithelial regeneration ↓
[92]

POST—Treatment post incubation with PFA. Concentrations converted into µg/mL for comparative reasons; ↑: increasing effect; ↓: decreasing effect; -: no effect.