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. 2022 Mar 14;10(3):611. doi: 10.3390/microorganisms10030611

Table 8.

Usefulness of screening methods with tests 1 and 2.

(CI 95%) Test 1 Test 2
Indicators AmpC ± ESBL AmpC Alone AmpC ± ESBL AmpC Alone
Prevalence 15.7% 9.5% 15.7% 9.5%
Sensitivity 31.3% (14.2–55.6) 55.6% (26.7–81.1) 62.5% (38.6–81.5) 88.9% (56.5–98)
Specificity 100% (95.7–100) 100% (95.7–100) 100% (95.7–100) 100% (95.7–100)
PPV 100% (56.6–100) 100 (55.6–100) 100% (72.2–100) 100% (67.6–100)
NPV 88.7% (80.8–93.5) 95.6% (89.1–98.3) 93.5% (86.5–97) 98.9% (93.8–99.8)
Validity Index 89.2% (81.7–93.9) 95.8% (89.7–98.4) 94.1% (87.8–97.3) 98.9% (94.3–99.8)
Youden’s Index 0.313 0.556 0.625 0.889

PPV: positive predictive value; NPV: negative predictive value; ESBL: extended-spectrum beta-lactamase; CI: confidence interval.