Table 1.
Fifteen selected significant KEGG pathways of the miR-183 family members (miR-182 higlighted in bold) (presented by p-value).
| KEGG Pathway | p-Value | #Genes | MiR-183 Cluster’ Members |
|---|---|---|---|
| Adherens junction | 3.67 × 10−14 | 34 | miR-182, miR-183, miR-96 |
| Fatty acid biosynthesis | 2.69 × 10−12 | 3 | miR-182 |
| Hippo signaling pathway | 3.69 × 10−8 | 37 | miR-182, miR-183 |
| Proteoglycans in cancer | 2.36 × 10−7 | 61 | miR-182, miR-183, miR-96 |
| Prostate cancer | 3.03 × 10−7 | 38 | miR-182, miR-183, miR-96 |
| Cell cycle | 3.86 × 10−6 | 40 | miR-182, miR-96 |
| FoxO signaling pathway | 4.96 × 10−6 | 48 | miR-182, miR-183, miR-96 |
| Estrogen signaling pathway | 7.15 × 10−5 | 30 | miR-182, miR-183, miR-96 |
| p53 signaling pathway | 0.000103754 | 27 | miR-182, miR-96 |
| Regulation of actin cytoskeleton | 0.000843268 | 27 | miR-183 |
| AMPK signaling pathway | 0.001045423 | 39 | miR-182, miR-96 |
| Pathways in cancer | 0.002560086 | 89 | miR-182, miR-183 |
| PI3K-Akt signaling pathway | 0.003008112 | 33 | miR-96 |
| ECM-receptor interaction | 0.0278908 | 8 | miR-96 |
| Axon guidance | 0.03842599 | 14 | miR-183 |