Correction to: Scientific Reports 10.1038/s41598-022-08516-2, published online 22 March 2022
The original version of this Article contained an error in Figure 6 where the red circles around the question marks were incorrectly added in the published figure.
The original Figure 6 and accompanying legend appear below.
Figure 6.
IL-6-dependent induction of LRG1 and proposed downstream angiopathic effector mechanisms. IL-6 induces LRG1 in endothelial cells, but not mural cells. LRG1 may then act in an autocrine loop on endothelial cells through the TGFβ receptor complex to activate canonical and non-canonical signalling that will modify endothelial cell function and induce vascular destabilising genes. In turn, the LRG1-mediated induction of angiocrine factors may result in indirect angiopathic effects on endothelial cells and mural cells. Alternatively, LRG1 may signal in a paracrine fashion directly on mural cells to drive destabilisation. Dashed lines with question marks represent speculative pathways. Created with Biorender.com.
The original Article has been corrected.