Figure 2.

Total number of shared and unique variants estimated to influence migraine and mental disorders. Results from the MiXeR analysis for migraine (MIG) and each of (A) bipolar disorder (BIP), (B) depression (DEP) and (C) schizophrenia (SCZ). Venn diagrams representing the unique and shared variants associated with migraine and each of bipolar disorder, depression and schizophrenia. Polygenic overlap is represented in a lighter shade, migraine in yellow, bipolar disorder in purple, depression in brown and schizophrenia in green. The numbers indicate the estimated number of variants in thousands per component with standard deviations in parentheses. The size of the circle reflects the extent of polygenicity for each disorder.