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Journal of Experimental & Clinical Cancer Research : CR logoLink to Journal of Experimental & Clinical Cancer Research : CR
. 2022 Mar 31;41:118. doi: 10.1186/s13046-022-02341-1

Correction to: Direct inhibition of ACTN4 by ellagic acid limits breast cancer metastasis via regulation of β-catenin stabilization in cancer stem cells

Neng Wang 1,2, Qi Wang 2, Hailin Tang 1, Fengxue Zhang 2, Yifeng Zheng 2, Shengqi Wang 2, Jin Zhang 2, Zhiyu Wang 2,, Xiaoming Xie 1,
PMCID: PMC8969376  PMID: 35361238

Correction to: J Exp Clin Cancer Res 36, 172 (2017)

https://doi.org/10.1186/s13046-017-0635-9

Following publication of the original article [1], minor errors we identified in Fig. 6d and Fig. S4; specifically:

  • Figure 6d: incorrect image used for shCtrl scratch image (24 h); correct image now used

  • Fig. S4: incorrect images used for the invasive MDA-MB-231 cells (25 μM EA); correct images now used

Fig. 6.

Fig. 6

ACTN4 promotes breast cancer proliferation and metastasis in vitro and in vivo. a Intracellular expression of ACTN4 was determined by Western blot (left) and real-time PCR (right) analysis, respectively; b ACTN4 expression was modified by transfecting recombinant plasmid or its shRNA in breast cancer cells and subjected to Western blotting (left) and real-time PCR (right) validation; c MTT and colony formation assay showed that ACTN4 silencing abrogated breast cancer cell proliferation while its overexpression promoted cell growth; d ACTN4 silencing inhibited the migration and invasion abilities of MDA-MB-231 cells; e ACTN4 silencing inhibited breast cancer growth and lung metastasis in vivo (*P < 0.05, **P < 0.01 versus control, values represented as the mean ± SD, n = 3)

The corrected figures, produced using the original data, are given here. The correction does not have any effect on the final conclusions of the paper.

Supplementary Information

13046_2022_2341_MOESM1_ESM.zip (2MB, zip)

Additional file 4. The wound healing and chamber invasive assay revealed that breast cancer cell migration and invasion were inhibited by EA in a time- and dose-dependent manner.

Contributor Information

Zhiyu Wang, Email: wangzhiyu976@126.com.

Xiaoming Xie, Email: xiexm@sysucc.org.cn.

Reference

  • 1.Wang N, Wang Q, Tang H, et al. Direct inhibition of ACTN4 by ellagic acid limits breast cancer metastasis via regulation of β-catenin stabilization in cancer stem cells. J Exp Clin Cancer Res. 2017;36:172. doi: 10.1186/s13046-017-0635-9. [DOI] [PMC free article] [PubMed] [Google Scholar]

Associated Data

This section collects any data citations, data availability statements, or supplementary materials included in this article.

Supplementary Materials

13046_2022_2341_MOESM1_ESM.zip (2MB, zip)

Additional file 4. The wound healing and chamber invasive assay revealed that breast cancer cell migration and invasion were inhibited by EA in a time- and dose-dependent manner.


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