Supplementary Methods Figure 1.
H&E and IHC workflow using specific antibodies to identify gland phenotypes. H&E is the primary histologic guide. Only intestinal glands do not express MUC5AC; however, glands transitioning from specialized to a mature intestinal phenotype may have weak MUC5AC (MUC5AClo) staining and are considered specialized. -ve, negative; +ve, positive.