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TBK1 activated JAK/STAT signaling. (a) KEGG analysis for the following signaling pathways of TBK1. (b) KEGG analytical results showed the positive regulation of TBK1 on JAK/STAT signaling. (c) ATDC5 cells were transfected with the pcTBK1 overexpression plasmid, siTBK1 or the negative controls. Phosphorylation of JAK1, JAK2 and STAT3 was detected by Western blotting.
