Figure 2.
Joint retention of SOD-NPs. (A) Representative images of healthy and OA mouse knee joints over 28 days after an intra-articular injection of IRDye 800CW–labeled SOD or SOD-NPs. (B) Quantitative analysis of time course radiant efficiency within knee joints after intra-articular injection of IRDye 800CW–labeled SOD or SOD-NPs. (n = 6 mice/group). (C) Quantitative analysis of area under the curve (AUC) based on fluorescence intensity profile in (B). (n = 6 mice/group). ***P < 0.001, ****P < 0.0001.