Abstract
Method
This study was conducted according to Arksey and O'Malley's framework. To investigate the evidence on the effects of Kinect-based rehabilitation, a search was executed in five databases (Web of Science, PubMed, Cochrane Library, Scopus, and IEEE) from 2010 to 2020.
Results
Thirty-three articles were finally selected by the inclusion criteria. Most of the studies had been conducted in the US (22%). In terms of the application of Kinect-based rehabilitation for stroke patients, most studies had focused on the rehabilitation of upper extremities (55%), followed by balance (27%). The majority of the studies had developed customized rehabilitation programs (36%) for the rehabilitation of stroke patients. Most of these studies had noted that the simultaneous use of Kinect-based rehabilitation and other physiotherapy methods has a more noticeable effect on performance improvement in patients.
Conclusion
The simultaneous application of Kinect-based rehabilitation and other physiotherapy methods has a stronger effect on the performance improvement of stroke patients. Better effects can be achieved by designing Kinect-based rehabilitation programs tailored to the characteristics and abilities of stroke patients.
1. Introduction
Stroke is the second most prevalent cause of mortality and disability worldwide. The prevalence of stroke will increase due to the aging of the population. Moreover, stroke happens in a larger number of young populations in low- and middle-income communities [1]. It damages the sensory, motor, perception, visual, and cognitive systems, disrupts the patients' ability to conduct daily activities, and impacts their quality of life and level of independence [2, 3].
Rehabilitation in stroke is a purposeful process to help the patients regain and retain their social, intelligence, mental, and physical abilities while also helping them perform their daily and social activities with some level of independence [4, 5]. Rehabilitation exercises should include specific, repetitive, intensive, meaningful, and motivational tasks to improve the patients' motor performance [6]. Starting rehabilitation immediately after a stroke greatly contributes to patients' performance improvement, and effective rehabilitation depends on the patients' adherence to exercise programs and their regular performance at home and physiotherapy clinics. The process of rehabilitation in stroke patients is a long one, and patients' follow-up of this process is seriously limited due to its heavy costs, the long distance to rehabilitation centers, lack of access to such centers, patients' motor limitations, and problems associated with commuting to the health-care centers [6–8]. Moreover, patients' motivation for rehabilitation, which is a key factor for following the treatment and improving the outcome, is reduced because of the prolonged duration of rehabilitation [7].
The use of technology in rehabilitation is increasing rapidly. One of these technologies is video games, which is known as an effective intervention in rehabilitation. Video games are a useful solution for stroke patients who are unable to perform daily activities in the real environment and also motivate and encourage people to do rehabilitation exercises and improve motor function in stroke patients [8]. Video games are a new and useful technology that allows the user to interact with a three-dimensional environment. Studies have shown that this technology is an effective, safe, feasible solution that facilitates rehabilitation treatment [9]. In addition, video games increase motivation and increase patient satisfaction and involvement [10, 11]. Studies show that video games are used for a wide range of disorders including balance, cognition, mobility, and improved motor function. Video games are a promising tool because they provide the repetitive, task-based, reward-based, and interactive situations needed to restore patient function after brain injury [12]. Kinect-based video games are a good tool for providing rehabilitation exercises in the form of games due to the features of Kinect and the limitations of stroke patients [13, 14]. The application of Kinect-based rehabilitation as a low-cost and flexible method is rapidly expanding [15]. Kinect contains an RGB camera (R for red, G for green, and B for blue), a depth sensor, and a layer of microphones to record body movements and detect faces and voices [16]. Microsoft Kinect is a markless motion capture system that presents innovative and exciting methods for offering a more enjoyable treatment and promoting motivation in and adherence to the treatment [17, 18]. A unique feature of Kinect is providing a method for interaction with the game without using any controllable or wearable device [19, 20].
Another feature of Kinect for patients is performing rehabilitation exercises at home with no need for a physiotherapist [21]. By providing exciting and innovative rehabilitation methods, Kinect enhances adherence to treatment through adding entertaining features to the treatment, lessening costs compared to traditional rehabilitation, and making rehabilitation more accessible [17, 22]. Two types of games, commercial and customized, are used in Kinect-based rehabilitation. Some studies have utilized commercial Kinect-based games for rehabilitation. Although these games had positive effects on the performance improvement of stroke patients, since they had been developed for healthy people for entertainment purposes and required a high level of speed and ability, stroke patients could not easily perform them due to their limited and diverse abilities [8, 23]. On the other hand, some studies have developed games customized to the abilities of stroke patients. These games, known as serious games, were aimed for something beyond mere entertainment, and the results show that they positively affect the performance improvement of patients [24, 25].
Today, serious games, especially exergames, are used by therapists as a tool for rehabilitation purposes [26, 27]. Exergaming involves physical activity and is directly related to the sport in the game, not to the game or sport itself. Many studies have introduced exercise games in rehabilitation to motivate, engage, and increase patient adherence to their treatments [28, 29]. Research confirms the motivational benefits of using exergames in rehabilitation regardless of their age or illness [30].
Based on the findings of systematic reviews on the clinical and technical evaluation of the Kinect sensor, the use of this rehabilitation system is acceptable due to its cost-effectiveness and adequate precision in movement tracking [22, 31, 32]. Various studies have been conducted on the validity and accuracy of Kinect in tracking movements and the effect of Kinect on rehabilitation and motor recovery. Research on the validity and accuracy of the Kinect sensor indicates that this sensor has sufficient precision in movement tracking [20, 31, 33, 34]. Studies on the effects of Kinect on the performance improvement of patients with neurological disorders (such as Parkinson's disease and multiple sclerosis) have also deemed this method effective [17, 31, 32, 35].
The aim of scoping review is to determine, retrieve, and summarize the research pertinent to special issues to identify the key concepts supporting a research domain and the major sources and available evidence [36]. Scoping reviews are conducted to answer more general questions. One of their advantages is determining the feasibility and necessity of conducting a systematic review in a specific domain [36, 37]. So far, no comprehensive study has been conducted on Kinect-based rehabilitation for stroke patients. Therefore, this scoping review focused on the effects of Kinect-based rehabilitation for stroke patients and its limitations and challenges. Accordingly, the following research questions were posed:
What is the effect of Kinect-based rehabilitation systems on the performance of stroke patients?
What is the main application domain of a Kinect-based rehabilitation system for stroke patients?
What are the limitations of utilizing Kinect-based rehabilitation systems for stroke patients?
2. Methods
The current scoping review adopted Arksey and O'Malley's methodology [36]. Based on this framework, a scoping review has five essential steps and one selective step: (1) identification of the research question; (2) recognition of pertinent researches; (3) selection of studies; (4) charting the data; and 5) summarizing and disseminating the results and (6) consultation exercise. The sixth step was omitted in this review. This scoping review was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Review (PRISMA-ScR) guidelines [38].
2.1. Eligibility Criteria
The main inclusion criteria for this review were as follows:
English articles published in peer-reviewed journals and conferences with an available full text
Articles published from 1 January 2010 to 13 October 2020
Articles using Kinect-based rehabilitation for stroke patients
Articles clinically evaluating and using Kinect for tracking movements and interactions in the rehabilitation system
2.2. Exclusion Criteria
Furthermore, the most important exclusion criteria for this review were as follows:
Review articles, case reports, case studies or study protocols, letter to the editor, correspondences, and conference papers (absence or lack of access to the full text)
Articles in languages other than English
Articles merely evaluating the accuracy and validity of Kinect and not clinically evaluating the use of Kinect for improving the conditions of stroke patients
Articles examining conditions other than stroke
2.3. Search Strategy and Information Sources
Articles were searched in five online databases (PubMed, Web of Science, Cochrane Library, IEEE Xplore, and Scopus). The search strategy comprised MeSH terms and other relevant keywords, and the two groups of terms were combined using Boolean operators AND and OR. The search was limited to the 2010-2020 period since Microsoft's first generation of Kinect sensors was introduced in November 2010 [10, 11]. The key terms used in this review was as follows: ((Stroke OR stroke rehabilitation) AND (Kinect OR Microsoft Kinect OR Xbox-Kinect OR virtual reality OR virtual reality exposure therapy OR virtual Reality exposure therapy OR virtual reality OR video games OR video games)). A summary of the characteristics of the included studies is provided in Table 1.
Table 1.
A summary of the characteristics of the included studies.
| # | First author (Ref) | Year | Country | Rehabilitation domain | Type of rehabilitation program | Number of sessions | Duration (week) | Outcome measures (mean (SD)) | Key findings | Technical limitations |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Sheehy [68] | 2020 | Canada | Balance and UE rehabilitation | Commercial game | 10-12 | 4 | Experimental group: pre/post differences for FIST were 3.4 (confidence interval [CI] 0.5; 6.3) Control group: pre/post differences for FIST were 5.3 (2.9; 7.7) |
The improvement in balance and upper extremities was the same in the intervention and control groups, and there was no difference between the two groups. | The Kinect-based rehabilitation program not being challenging and customized to the users' abilities |
| 2 | Shahmoradi [67] | 2020 | Iran | UE rehabilitation | Customized game | 10 | 4 | Games have positive effects on the horizontal abduction of shoulder (16.26 ± 23.94, P = 0.02), horizontal adduction of shoulder (59.24 ± 74.76, P = 0.01), supination of wrist (10.68 ± 53.52, P = 0.02), elbow flexion (0.1 ± 1.5, P = 0.01), and wrist flexion (0.06 ± 1.34, P = 0.03). | Kinect-based rehabilitation improved the upper extremity range of motion. | No game being designed for fingers due to an imprecise Kinect sensor and no patient progress reporting feature in the software |
| 3 | Norouzi-Gheidari [49] | 2020 | Canada | UE rehabilitation | Customized game | 10 | 4 | The efficacy measures showed statistically meaningful improvements in the activities of daily living measures (i.e., MAL-QOM (motor activity log-quality of movement) and both mobility and physical domains of the SIS (stroke impact scale) with mean difference of 1.0%, 5.5%, and 6.7% between the intervention and control group, respectively) at postintervention. | Compared to the use of routine treatment methods alone, the simultaneous application of Kinect-based rehabilitation and other physiotherapy methods has a stronger effect on the performance improvement of upper extremities. | Not mentioned |
| 4 | Maier [39] | 2020 | Spain | Cognitive rehabilitation | Customized game | 10 | 6 | The experimental group showed improvements in attention (P < .01), spatial awareness (P < .01), and generalized cognitive functioning (P < .001). | Kinect-based rehabilitation has positive effects on stroke patients' attention, spatial awareness, and depression. | Not mentioned |
| 5 | Cano-Mañas [50] | 2020 | Spain | Balance rehabilitation | Commercial game | 40 | 5 | Modified Rankin scores (P < 0.01) and the Barthel index (P < 0.01). | The combination of Kinect-based rehabilitation and other physiotherapy methods improves patients' balance, performance, and motivation. | Commercial Kinect-based games are not designed specifically for stroke patients, and it is difficult to adapt them to the patients' abilities |
| 6 | Mokhtar [40] | 2019 | Egypt | UE rehabilitation | Customized game | 18 | 6 | The modified Barthel index score for the study group (P < 0.05). Grip muscle strength for the study group (P < 0.05). The modified Barthel index score for the control group at the end of the treatment was significantly lower than in the study group (P < 0.05). |
Kinect-based rehabilitation improves upper extremity performance. | Not mentioned |
| 7 | Ho [51] | 2019 | Taiwan | Functional recovery | Customized game | 7 | 1 | Functional outcomes (mRS improvement from the baseline; − 0.58 vs. − 0.23, P < 0.001) and reduced medical cost (Taiwan dollar; 49474 vs. 66306, P < 0.005). | Compared to the use of routine treatment methods alone, the simultaneous application of Kinect-based rehabilitation and other physiotherapy methods has a stronger effect on the performance improvement of stroke patients. | Not mentioned |
| 8 | Foreman [41] | 2019 | USA | UE rehabilitation | Customized game | 1 | — | High dose of reaching repetitions (461 ± 184), with an average of 81% being successful and 19% involving compensatory trunk flexion. | Kinect-based rehabilitation program increases the repetitions of movements, enhances motivation, and leads to upper extremity performance improvement in stroke patients. | (1) The games are slow and there is no patient progress reporting feature (2) Displaying the feedbacks is not appropriate for some patients. Providing sound feedbacks, using a larger monitor, and keeping the appropriate distance from the Kinect sensor are better for patients with visual impairment (3) Tracking with Kinect sensor is not completely reliable. It does not precisely track some movements, causes problems in interaction with games, and leads to incorrect feedback |
| 9 | Boone [42] | 2019 | USA | UE rehabilitation | Customized game | 24 | 12 | Fugl-Meyer Assessment; preintervention (34.4 ± 10.6); postintervention (42.7 ± 10.4). | Kinect-based rehabilitation program increases the repetitions of movements, enhances motivation, and leads to upper extremity performance improvement in stroke patients. | Not mentioned |
| 10 | Aramaki [43] | 2019 | Brazil | Functional recovery | Commercial game | 36 | 12 | COPM; pretest performance: 2.12 (0.81). COPM; posttest performance: 6.40 (1.82) (P < 0.001) COPM; pretest satisfaction: 1.64 (0.88) COPM; posttest satisfaction: 6.22 (1.78) (P < 0.001) |
Kinect-based rehabilitation program is an appropriate tool for patients' performance improvement, increasing their motivation, and enhancing their treatment adherence. | Not mentioned |
| 11 | Adomavičienė [76] | 2019 | Lithuania | UE and cognitive rehabilitation | Customized game | 10 | 2 | Self-care (P < 0.05). Decreased muscle tone, improved shoulder and elbow ROMs, hand dexterity, and grip strength (P < 0.05). Anxiety level (P < 0.05). |
Kinect-based rehabilitation improves the upper extremity performance and cognitive ability. | Not mentioned |
| 12 | Triandafilou [61] | 2018 | USA | UE rehabilitation | Customized game | 9 | 3 | Arm displacement averaged 350 m for each VERGE training session. | Kinect-based rehabilitation increases the movements and patients' motivation and is an effective tool for rehabilitation at home. | The complex scenario of the games requires high cognitive abilities and causes problems in patients' learning and coordination |
| 13 | Schaham [44] | 2018 | Israel | UE and LE rehabilitation | Commercial game | 4-22 | 12 | — | Kinect-based rehabilitation is an appropriate tool for rehabilitation, increases patients' motivation, and leads to performance improvement. | Commercial Kinect-based games that are not designed specifically for stroke patients sometimes cause problems for patients in controlling and learning the games |
| 14 | Liao [45] | 2018 | USA | UE rehabilitation | Customized game | 15 | 5 | Fugl-Meyer Assessment scores (P = 0.001). Wolf Motor Function Test (P = 0.008). Active range of motion (P < 0.05). Stroke impact scale-hand function (P = 0.016). |
Kinect-based rehabilitation improves the upper extremity performance of stroke patients. | Not mentioned |
| 15 | Kim [52] | 2018 | South Korea | UE rehabilitation | Customized game | 50 | 10 | FMA: sham (46.8 ± 16.0) and the real VR group (49.4 ± 14.2) (P = .937 in intention to treat analysis). | Kinect-based rehabilitation will be more effective if used in combination with other physiotherapy methods. | (1) The activities in the games are not similar to the patients' real-life tasks (2) Due to the games' poor user interface, the patients depend on the physiotherapist for selecting the type of game compatible with their abilities |
| 16 | Ikbali Afsar [53] | 2018 | Turkey | UE rehabilitation | Commercial game | 20 | 4 | At posttreatment, a statistically significant increase was found in both groups in the upper extremity and hand Brunnstrom stages, FMAUE, FIM self-care subscore, and BBT score (P < .001). | Kinect-based rehabilitation will be more effective if used in combination with other physiotherapy methods. | Commercial Kinect-based games are not designed specifically for stroke patients, and it is difficult to adapt the games to the patients' abilities |
| 17 | Held [63] | 2018 | Switzerland | Balance rehabilitation | Customized game | 36 | 12 | — | Kinect-based rehabilitation is a safe and effective method of providing standard rehabilitation at home. | Not mentioned |
| 18 | Grigoras [54] | 2018 | Romania | UE rehabilitation | Customized game | 12 | 3 | FMA (P = 0.039). | Kinect-based rehabilitation will be more effective if used in combination with other physiotherapy methods. | The game cannot be played at home in the absence of a physiotherapist and without training due to its advanced features |
| 19 | Aşkın [55] | 2018 | Turkey | UE rehabilitation | Customized game | 20 | 5 | FMA (P < 0.05). BBT (P < 0.05). Motricity index (P < 0.05). |
Kinect-based rehabilitation will be more effective if used in combination with other physiotherapy methods. | Not mentioned |
| 20 | Türkbey [56] | 2017 | Turkey | UE rehabilitation | Commercial game | 20 | 5 | BBT (P < 0.005). WMFT—performance time score (P < 0.005). WMFT—functional ability score (P < 0.005). FIM self-care score (P < 0.018). BMRS—upper extremity (P < 0.010). |
Kinect-based rehabilitation is a safe and reliable method for upper extremity performance improvement and will be more effective if used in combination with other physiotherapy methods. | Commercial Kinect-based games are not designed specifically for stroke patients, and it is difficult to adapt the games to the patients' abilities |
| 21 | Park [57] | 2017 | South Korea | LE and balance rehabilitation | Commercial game | 42 | 6 | FMS (P < 0.005). BBT (P < 0.005). TUG (P < 0.005). |
Kinect-based rehabilitation will be more effective if used in combination with other physiotherapy methods. | Commercial Kinect-based games are not designed specifically for stroke patients, and it is difficult to adapt the games to the patients' abilities |
| 22 | Moldovan [46] | 2017 | Romania | UE and balance rehabilitation | Customized game | 10 | 2 | Final ARAT score improved from 46 to 57 points (24% amendment), the Fugl-Meyer test score improved from 46 to 52 (13% amendment), and the Berg Balance Scale improved from 43 to 49 points (14% amendment). | Kinect-based rehabilitation improves patients' upper extremity performance, balance, and treatment adherence. | Not mentioned |
| 23 | Maier [47] | 2017 | Spain | Cognitive rehabilitation | Customized game | 10 | 2 | — | Kinect-based rehabilitation is a novel and promising approach to cognitive rehabilitation. | Kinect-based rehabilitation programs could not be adapted to the patients' cognitive abilities |
| 24 | Lee [48] | 2017 | Taiwan | Balance rehabilitation | Commercial game | 12 | 6 | BS (P = 0.001). TUG-cog test (P = 0.005). |
Kinect-based rehabilitation is an effective method for balance improvement and will be more effective if used in combination with other physiotherapy methods. | Commercial Kinect-based games are not designed specifically for stroke patients, and it is difficult to adapt the games to the patients' abilities. |
| 25 | Tsoupikova [62] | 2016 | USA | UE rehabilitation | Customized game | 9 | 3 | — | Kinect-based rehabilitation improves patients' upper extremity performance and adherence to treatment. | Not mentioned |
| 26 | Lai [64] | 2016 | Taiwan | Balance rehabilitation | Customized game | 10 | 2 | BBS (P < 0.005). | Kinect-based rehabilitation improves patients' balance and adherence to treatment and can be used at home. | Not mentioned |
| 27 | Shin [58] | 2015 | South Korea | UE rehabilitation | Customized game | 20 | 5 | FMA (P < 0.079). Emotional problems (P = 0.047). Depression (P = 0.017). Upper extremity function (P = 0.001) |
If used in combination with other physiotherapy methods, Kinect-based rehabilitation will lead to upper extremity performance improvement in stroke patients. | Not mentioned |
| 28 | Proffitt [65] | 2015 | USA | UE rehabilitation | Customized game | 30 | 6 | FMA (P < 0.05) | Kinect-based rehabilitation is a cost-effective, safe, and effective method for performance improvement of stroke patients and can be used at home. | (1) No choice to the type of game (2) Not displaying more feedbacks on the monitor (3) Lack of a help feature for troubleshooting and solving technical issues (4) Poor user interface and problems with findings the icons |
| 29 | Lloréns [18] | 2015 | Spain | Balance rehabilitation | Customized game | 36 | 12 | Berg Balance Scale (ηp(2) = .68; P = .001). Balance (ηp(2) = .24; P = .006). Gait (ηp(2) = .57; P = .001). |
The combination of Kinect-based rehabilitation and other physiotherapy methods improves patients' balance and adherence to treatment. | Not mentioned |
| 30 | Brokaw [24] | 2015 | USA | UE rehabilitation | Customized game | 20 | 4 | Stroke Impact Scale-16; before: 67 after: 68. Fugl-Meyer; before: 34 after:39. Shoulder; before: 17 after: 19. Wrist; before: 6 after: 6. Hand; before: 11 after: 14. |
The combination of Kinect-based rehabilitation and other physiotherapy methods improves patients' upper extremity performance and adherence to treatment. | Not mentioned |
| 31 | Singh [66] | 2014 | Malaysia | Balance rehabilitation | Commercial game | 12 | 6 | Timed Up and Go Test; F (1, 26) = 5.83, P = 0.02; and the 30-second Sit to Stand test; F (1, 26) = 13.50, P = 0.001. | As a complementary technique in combination with other physiotherapy methods, Kinect-based rehabilitation leads to performance improvement and can be used at home. | Not mentioned |
| 32 | Sin [59] | 2013 | South Korea | UE rehabilitation | Commercial game | 12 | 6 | FMA (P < 0.05). BBS (P < 0.05). |
The combination of Kinect-based rehabilitation and other physiotherapy methods improves patients' upper extremity performance and adherence to treatment. | Not mentioned |
| 33 | Lee [8] | 2013 | South Korea | UE rehabilitation | Commercial game | 18 | 6 | FMA (P < 0.05) | The combination of Kinect-based rehabilitation and other physiotherapy methods improves patients' upper extremity performance and adherence to treatment. | Not mentioned |
| 34 | Wiederhold [60] | 2012 | Spain | Balance rehabilitation | Commercial game | 20 | 4 | BBS (P < 0.05) | Kinect-based rehabilitation is an effective tool that improves the balance of stroke patients. | Not mentioned |
UE: upper extremity; LE: lower extremity; COPM: Canadian Occupational Performance Measure; BBT: Box and Block Test; FIM: Functional Independence Measure; FMA: Fugl-Meyer Assessment; WMFT: Wolf Motor Function Test; BMRS: Brunnstrom Motor Recovery Stage; TUG: Timed Up and Go Test; ARAT: Action Research Arm Test; BBS: Berg Balance Scale.
2.4. Study Selection
The electronic search was performed in the five mentioned databases. Also, hand-searching was performed in Google Scholar, and 58 articles were retrieved. The retrieved articles were then inputted to EndNote, and the duplicates were identified and removed by using the software. Subsequently, the titles and abstracts of the articles were reviewed by two authors according to the research questions and objectives. In the next step, the full text of the papers was examined by two authors concerning the inclusion and exclusion criteria. Any disagreements between the authors were resolved by discussions.
2.5. Data Extraction, Charting, and Synthesis
Data extraction was executed by using a form including the first author's name (reference), year of publication, country, the domain of rehabilitation, type of rehabilitation program (commercial vs. customized), main findings, and technical limitations of the Kinect-based rehabilitation program. The data were obtained by two authors, and disagreements were resolved upon discussions. Finally, the data extracted from the articles were inputted to Microsoft Excel for classification, synthesis, and reporting of the results.
3. Results
3.1. Selection of Sources of Evidence
Totally, 1196 articles were retrieved by searching in the databases. In the next step, by using EndNote, 184 duplicates were removed, and 954 articles remained. Subsequently, the titles and abstracts of the papers were reviewed, 856 papers were removed, and 98 remained. Then, the full text of the articles was examined, 64 articles were removed, and finally, 34 articles were included in this scoping review. Figure 1 displays the article selection process.
Figure 1.

Scoping review flowchart.
3.2. Characteristics of the Sources of Evidence
The data extracted from the articles were recorded in the data extraction form (Table 1). The majority of the studies had been conducted in the US (n = 7, 22%), followed by Spain and South Korea (n = 5, 15%).
Following the invention of Kinect in 2010, the number of studies on the use of Kinect-based rehabilitation programs for stroke patients increased (Figure 2). However, no study based on the inclusion and exclusion criteria had been conducted in 2010, 2011, and 2014. The majority of the studies had been conducted in 2018 (n = 8).
Figure 2.

Distribution of the research papers based on publication year.
3.3. Classification of the Studies Based on the Rehabilitation Domain
In the analysis of the domain of rehabilitation for stroke patients, most studies had focused on upper extremities (n = 22), followed by balance (n = 10), cognitive rehabilitation (n = 3), lower body (n = 2), and functional recovery (n = 2) (Figure 3).
Figure 3.

Distribution of the papers based on rehabilitation domain.
In terms of the effects of Kinect-based rehabilitation programs, the majority of the studies had evaluated it as positive leading to the performance improvement of stroke patients [39–48]. Most studies had also mentioned that, compared to the use of routine treatment methods alone, the simultaneous application of Kinect-based rehabilitation and other physiotherapy methods has a stronger effect on the performance improvement of stroke patients [18, 24, 48–60].
Furthermore, the results revealed that the use of a Kinect-based rehabilitation program increases the repetitions of the movements, improves motivation, promotes the quality of life, and enhances adherence to treatment [18, 41–44, 46, 61, 62]. Some studies had employed telerehabilitation, reporting that Kinect-based rehabilitation is a safe and effective method for providing standard rehabilitation at home, whereby patients do not have to be present at physiotherapy clinics [59, 61, 63–66]. There was only one study in which the use of Kinect-based rehabilitation had the same effect on the intervention and control groups, and there was no difference between the two groups [67].
3.3.1. Upper Extremities
The results of this study showed that 56% of the articles were in the field of upper limb rehabilitation. Patients' movements in the study were measured using Fugl-Meyer Assessment and Brunnstrom Motor Recovery Stage, which used Kinect-based rehabilitation games to improve patients' shoulder, elbow, wrist, and finger movements and ultimately to improve daily activities. There was an increase in patients' quality of life.
3.3.2. Balance
The results of this study showed that 26% of the articles were in the field of balance rehabilitation. In the studies studied using Box and Block Test, Barthel Index, and Berg Balance Scale, it was measured that the use of Kinect-based rehabilitation games improved patients' balance.
3.3.3. Cognitive Rehabilitation
The results of this study showed that 8% of the articles were in the field of cognitive rehabilitation. The results of the studies showed that the use of Kinect-based rehabilitation games improved patients' attention, spatial awareness, and generalized cognitive functioning.
3.3.4. Lower Body
The results of this study showed that 5% of the articles were in the field of lower limb rehabilitation. In these studies, the Timed Up and Go Test and Fugl-Meyer Assessment erew used to measure lower limb movements, and the results showed that it improved lower limb movement.
3.4. Technical Limitations of Kinect-Based Rehabilitation Systems
In terms of the type of rehabilitation program used for stroke patients, the majority of the studies had designed the rehabilitation program tailored to the status and abilities of the patients (n = 13, 38%), while the other studies had utilized commercial Kinect-based programs (n = 21, 62%). Among the studies using commercial Kinect-based programs, technical limitations mostly included not challenging enough, lack of customization to the patients' abilities, complexity and difficulty of use, dependency on the therapist due to complexity, and the content of the programs being radically different from the daily activities of stroke patients [44, 48, 50, 53, 56, 68]. In the studies designing games customized to the abilities of stroke patients, technical limitations included the low speed of the games, the use of inappropriate feedback, insufficient precision of movement tracking, the complexity of games and difficulty of use, inappropriate user interface, dependence on the therapist, and not customized to and compatibility with the abilities of patients (Figure 4) [41, 47, 52, 54, 61, 65].
Figure 4.

Distribution of the papers based on technical limitations.
4. Discussion
This scoping review investigated the effect of using Kinect-based rehabilitation systems on the performance improvement of stroke patients, the rehabilitation domain, and technical limitations. The reviewed articles were published since 2010, when Microsoft-invented Kinect was examined [10, 11]. The results revealed that Kinect-based virtual rehabilitation leads to motor recovery in stroke patients. This type of rehabilitation is an effective and promising method owing to its low cost, flexibility, providing repetitive exercises, and motivation for the patients.
The most important feature of Kinect is that there is no need for any wearables during rehabilitation [20]. This feature of Kinect-based rehabilitation increases the repetitions of the movements, promotes motivation, enhances the quality of life, and increases adherence to treatment [18, 41–44, 46, 61, 62]. Moreover, due to its cost-effectiveness, flexibility, and telerehabilitation feature, the use of Kinect-based rehabilitation is a safe and effective method for providing standard rehabilitation at home [59, 61, 63–66]. The results of this study show that the use of Kinect-based rehabilitation games improves motor function in the upper and lower limbs and balance and improves cognitive function in improving stroke patients. These results are in line with the results of other similar studies in the field of using Kinect-based rehabilitation in improving the motor function of the upper [69], lower limbs [70], balance [71], and cognition [72].
Most studies had also mentioned that, compared to the use of routine treatment methods alone, the simultaneous application of Kinect-based rehabilitation and other physiotherapy methods has a stronger effect on the performance improvement of stroke patients. Regarding the positive outcome of simultaneous use of Kinect-based rehabilitation and other physiotherapy methods, the results of the present research are consistent with those of other papers [73, 74].
Despite all these advantages, some studies utilizing commercial Kinect-based programs reported different effects on the performance improvement of stroke patients; the reason was the limitations of these programs such as not challenging enough, not being customized to the patients' abilities, complexity, dependency on the therapist due to the complexity of the games, and the difference between the content of the games with patients' daily activities [43, 44, 50, 56, 57, 68]. Although some of these programs will be beneficial in combination with other rehabilitation methods, as they have been designed for the healthy population and entertainment purposes, they require rapid and difficult movements that may not be compatible with the abilities of stroke patients [23, 75].
On the other hand, some studies had developed games customized to the abilities of stroke patients and reported positive effects on their motor recovery [42, 50, 53, 56, 61, 62]. These results are in line with the findings of other researches [25, 73]. To promote the effects of Kinect-based rehabilitation programs, it is necessary to pay attention to the characteristics of the patients and their abilities in the program's development process. The use of clear feedback, presenting challenges appropriate for patients' abilities [60], telemonitoring patients by the therapist [20], using rewards [69], and including the socialization feature to induce a sense of competition between patients, is essential in this process.
To promote neural plasticity in rehabilitation programs, tailor-made rehabilitation systems are promising tools for patients. Furthermore, appropriate feedback should be provided to actively engage patients in better motor recovery. One of the essential elements in rehabilitation programs is to keep the patients motivated and engaged. In this way, caregivers should provide suitable feedback to correctly execute the exercise. The caregiver should change the different parameters of exercise to make it challenging and simultaneously possible for executing.
Since the therapist cannot regularly monitor and evaluate the patient's condition in Kinect-based rehabilitation systems, using different sensors such as brain and body wearable sensors can receive more data to help better assess the patient. Captured data should be interpreted and presented by utilizing graphs to simply be understood by physicians. To enhance the efficacy of rehabilitation systems, the user interface should be designed by considering both patients' restrictions and caregivers' needs.
5. Limitations and Future Directions
One limitation of the current study was the diversity in the type of studies and the small samples of some studies, which pose problems in drawing definitive conclusions about the positive effects of Kinect-based rehabilitation on the motor recovery of stroke patients. Lack of access to the full text of some papers was another limitation. About the positive effect of customized Kinect-based rehabilitation programs which are tailored to the abilities of stroke patients, it is suggested more research be conducted on the design framework of such programs and their effects on the motor recovery of stroke patients. Furthermore, developing the rehabilitation systems should concentrate on a range of complex factors such as patients living environment, social environment, different challenges of daily living, and patients' skills in using various technologies. Furthermore, developing systems with a concentration on supporting personal goals and performing the rehabilitative exercise in a competitive atmosphere may increase progress over time. It will be necessary to conduct different clinical trials in large sample size, as well as different devices to determine which factors have a greater effect in achieving a better outcome. Furthermore, performing a meta-analysis study to investigate whether rehabilitation programs are beneficial in improving patients function in stroke is essential.
6. Conclusion
Because of some limitations such as the costs of rehabilitation, the long distance to rehabilitation centers, lack of access to such centers, patients' motor limitations, and commute problems, patients with stroke lose motivation to follow treatment. The application of Kinect-based rehabilitation is an effective solution for creating motivation and improving adherence to rehabilitation programs in stroke patients. Kinect-based rehabilitation will be more effective on the performance improvement of these patients if used as a complementary technique in combination with other rehabilitation methods. Furthermore, to promote effects on motor recovery, it is essential to pay attention to the design of rehabilitation programs customized to the abilities of stroke patients.
Acknowledgments
This study is supported by the Tehran University of Medical Sciences (grant no. 38639_31_02_97).
Additional Points
Key messages. (i) Kinect-based rehabilitation is an effective and promising solution that improves the motivation, adherence to treatment, and motor function of stroke patients. (ii) Compared to the use of routine treatment methods alone, the simultaneous application of Kinect-based rehabilitation and other physiotherapy methods has a stronger effect on the performance improvement of stroke patients. (iii) Kinect-based rehabilitation programs developed based on the abilities of stroke patients have more pronounced effects on performance improvement compared to commercial Kinect-based programs.
Conflicts of Interest
The authors have no conflicts of interest relevant to this article to disclose.
References
- 1.Katan M., Luft A. Global burden of stroke. Seminars in Neurology . 2018;38(2):208–211. doi: 10.1055/s-0038-1649503. [DOI] [PubMed] [Google Scholar]
- 2.Hochstenbach J., Prigatano G., Mulder T. Patients’ and relatives’ reports of disturbances 9 months after stroke: subjective changes in physical functioning, cognition, emotion, and behavior. Archives of Physical Medicine and Rehabilitation . 2005;86(8):1587–1593. doi: 10.1016/j.apmr.2004.11.050. [DOI] [PubMed] [Google Scholar]
- 3.Faria-Fortini I., Michaelsen S. M., Cassiano J. G., Teixeira-Salmela L. F. Upper extremity function in stroke subjects: relationships between the international classification of functioning, disability, and health domains. Journal of Hand Therapy . 2011;24(3):257–265. doi: 10.1016/j.jht.2011.01.002. [DOI] [PubMed] [Google Scholar]
- 4.Rensink M., Schuurmans M., Lindeman E., Hafsteinsdottir T. Task-oriented training in rehabilitation after stroke: systematic review. Journal of Advanced Nursing . 2009;65(4):737–754. doi: 10.1111/j.1365-2648.2008.04925.x. [DOI] [PubMed] [Google Scholar]
- 5.Lang C. E., Lohse K. R., Birkenmeier R. L. Dose and timing in neurorehabilitation: prescribing motor therapy after stroke. Current Opinion in Neurology . 2015;28(6):549–555. doi: 10.1097/WCO.0000000000000256. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 6.Saposnik G., Levin M., for the Stroke Outcome Research Canada (SORCan) Working Group Virtual reality in stroke rehabilitation: a meta-analysis and implications for clinicians. Stroke . 2011;42(5):1380–1386. doi: 10.1161/STROKEAHA.110.605451. [DOI] [PubMed] [Google Scholar]
- 7.Maclean N., Pound P., Wolfe C., Rudd A. The concept of patient motivation: a qualitative analysis of stroke professionals’ attitudes. Stroke . 2002;33(2):444–448. doi: 10.1161/hs0202.102367. [DOI] [PubMed] [Google Scholar]
- 8.Lee G. Effects of training using video games on the muscle strength, muscle tone, and activities of daily living of chronic stroke patients. Journal of Physical Therapy Science . 2013;25(5):p. 595. doi: 10.1589/jpts.25.595. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 9.Cho S., Ku J., Cho Y. K., et al. Development of virtual reality proprioceptive rehabilitation system for stroke patients. Computer Methods and Programs in Biomedicine . 2014;113(1):258–265. doi: 10.1016/j.cmpb.2013.09.006. [DOI] [PubMed] [Google Scholar]
- 10.Chen M.-H., Huang L.-L., Wang C.-H. Developing a digital game for stroke patients’ upper extremity Rehabilitation – Design, Usability and Effectiveness Assessment. Procedia Manufacturing . 2015;3:6–12. doi: 10.1016/J.PROMFG.2015.07.101. [DOI] [Google Scholar]
- 11.Zhang Z. Microsoft Kinect sensor and its effect. IEEE Multimedia . 2012;19(2):4–10. doi: 10.1109/MMUL.2012.24. [DOI] [Google Scholar]
- 12.Tatla S. K., Shirzad N., Lohse K. R., et al. Therapists' perceptions of social media and video game technologies in upper limb rehabilitation. JMIR Serious Games . 2015;3(1) doi: 10.2196/games.3401. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 13.Staiano A. E., Flynn R. Therapeutic uses of active videogames: a systematic review. Games for Health Journal . 2014;3(6):351–365. doi: 10.1089/g4h.2013.0100. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 14.Almasi S., Shahmoradi L., Ansari N. N., Honarpishe R. Kinect-based virtual rehabilitation for upper extremity motor recovery in chronic stroke. 2020 International Serious Games Symposium (ISGS); December, 2020; Tehran, Iran. pp. 51–60. [Google Scholar]
- 15.Zirbel C., Zhang X., Hughes C. The VRehab system: a low-cost mobile virtual reality system for post-stroke upper limb rehabilitation for medically underserved populations. 2018 IEEE Global Humanitarian Technology Conference (GHTC)); 2018; San Jose, CA, USA. pp. 1–8. [Google Scholar]
- 16.Rashid F. A. N., Suriani N. S., Nazari A. Kinect-based physiotherapy and assessment: a comprehensive Review. Indonesian Journal of Electrical Engineering and Computer Science . 2018;11(3):1176–1187. doi: 10.11591/ijeecs.v11.i3.pp1176-1187. [DOI] [Google Scholar]
- 17.Webster D., Celik O., rehabilitation Systematic review of Kinect applications in elderly care and stroke rehabilitation. Journal of Neuroengineering and Rehabilitation . 2014;11(1):p. 108. doi: 10.1186/1743-0003-11-108. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 18.Lloréns R., Noé E., Colomer C., Alcañiz M. Effectiveness, usability, and cost-benefit of a virtual reality–based telerehabilitation program for balance recovery after stroke: a randomized controlled trial. Archives of Physical Medicine and Rehabilitation . 2015;96(3):418–425. doi: 10.1016/j.apmr.2014.10.019. [DOI] [PubMed] [Google Scholar]
- 19.Ebert D., Metsis V., Makedon F. Development and evaluation of a unity-based, Kinect-controlled avatar for physical rehabilitation. Proceedings of the 8th ACM International Conference on PErvasive Technologies Related to Assistive Environments; 2015; Corfu, Greece. pp. 1–2. [Google Scholar]
- 20.Bonnechère B., Jansen B., Salvia P., et al. Validity and reliability of the Kinect within functional assessment activities: comparison with standard stereophotogrammetry. Gait & Posture . 2014;39(1):593–598. doi: 10.1016/j.gaitpost.2013.09.018. [DOI] [PubMed] [Google Scholar]
- 21.Knippenberg E., Spooren A. Opportunities of markerless motion detection systems for use in neurological rehabilitation: a qualitative study on patient and therapist perspective. Austin Journal of Robotics & Automation . 2016;3:1–5. [Google Scholar]
- 22.Mousavi Hondori H., Khademi M. A review on technical and clinical impact of Microsoft Kinect on physical therapy and rehabilitation. Journal of Medical Engineering . 2014;2014 doi: 10.1155/2014/846514.846514 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 23.Taylor M. J., McCormick D., Shawis T., Impson R., Griffin M. Activity-promoting gaming systems in exercise and rehabilitation. Journal of Rehabilitation Research and Development . 2011;48(10):1171–1186. doi: 10.1682/jrrd.2010.09.0171. [DOI] [PubMed] [Google Scholar]
- 24.Brokaw E. B., Eckel E., Brewer B. R., Care H. Usability evaluation of a kinematics focused Kinect therapy program for individuals with stroke. Technology and Health Care . 2015;23(2):143–151. doi: 10.3233/THC-140880. [DOI] [PubMed] [Google Scholar]
- 25.Chang Y.-J., Chen S.-F., Huang J.-D. A Kinect-based system for physical rehabilitation: a pilot study for young adults with motor disabilities. Research in Developmental Disabilities . 2011;32(6):2566–2570. doi: 10.1016/j.ridd.2011.07.002. [DOI] [PubMed] [Google Scholar]
- 26.Valladares-Rodríguez S., Pérez-Rodríguez R., Anido-Rifón L., Fernández-Iglesias M. Trends on the application of serious games to neuropsychological evaluation: a scoping review. Journal of Biomedical Informatics . 2016;64:296–319. doi: 10.1016/j.jbi.2016.10.019. [DOI] [PubMed] [Google Scholar]
- 27.Ghisio S., Kolykhalova K., Volpe G., et al. Designing a platform for child rehabilitation exergames based on interactive sonification of motor behavior. Proceedings of the 4th EAI International Conference on Smart Objects and Technologies for Social Good; 2018; Bologna, Italy. pp. 208–213. [Google Scholar]
- 28.Proffitt R., Sevick M., Chang C. Y., Lange B. User-centered design of a controller-free game for hand rehabilitation. Games Health Journal . 2015;4(4):259–264. doi: 10.1089/g4h.2014.0122. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 29.Avola D., Cinque L., Foresti G. L., Marini M. R. An interactive and low-cost full body rehabilitation framework based on 3D immersive serious games. Journal of Biomedical Informatics . 2019;89:81–100. doi: 10.1016/j.jbi.2018.11.012. [DOI] [PubMed] [Google Scholar]
- 30.Barry G., Galna B., Rochester L. The role of exergaming in Parkinson's disease rehabilitation: a systematic review of the evidence. Journal of Neuroengineering and Rehabilitation . 2014;11(11):p. 33. doi: 10.1186/1743-0003-11-33. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 31.Clark R. A., Pua Y.-H., Fortin K., et al. Validity of the Microsoft Kinect for assessment of postural control. Gait & Posture . 2012;36(3):372–377. doi: 10.1016/j.gaitpost.2012.03.033. [DOI] [PubMed] [Google Scholar]
- 32.Knippenberg E., Verbrugghe J., Lamers I., Palmaers S., Timmermans A., Spooren A. Markerless motion capture systems as training device in neurological rehabilitation: a systematic review of their use, application, target population and efficacy. Journal of Neuroengineering and Rehabilitation . 2017;14(1):p. 61. doi: 10.1186/s12984-017-0270-x. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 33.Díaz-Monterrosas P.-R., Posada-Gómez R., Martinez Sibaja A., Aguilar-Lasserre A., Juárez Martínez U., Trujillo-Caballero J. A brief review on the validity and reliability of Microsoft Kinect sensors for functional assessment applications. Advances in Electrical and Computer Engineering . 2018;18(1):131–136. doi: 10.4316/AECE.2018.01016. [DOI] [Google Scholar]
- 34.Galna B., Barry G., Jackson D., Mhiripiri D., Olivier P., Rochester L. Accuracy of the Microsoft Kinect sensor for measuring movement in people with Parkinson's disease. Gait & Posture . 2014;39(4):1062–1068. doi: 10.1016/j.gaitpost.2014.01.008. [DOI] [PubMed] [Google Scholar]
- 35.Peters M. D., Godfrey C. M., Khalil H., McInerney P., Parker D., Soares C. B. Guidance for conducting systematic scoping reviews. International Journal of Evidence-Based Healthcare . 2015;13(3):141–146. doi: 10.1097/XEB.0000000000000050. [DOI] [PubMed] [Google Scholar]
- 36.Arksey H., O'Malley L. Scoping studies: towards a methodological framework. International Journal of Social Research Methodology . 2005;8(1):19–32. doi: 10.1080/1364557032000119616. [DOI] [Google Scholar]
- 37.Munn Z., Peters M. D. J., Stern C., Tufanaru C., McArthur A., Aromataris E. Systematic review or scoping review? Guidance for authors when choosing between a systematic or scoping review approach. BMC Medical Research Methodology . 2018;18(1):p. 143. doi: 10.1186/s12874-018-0611-x. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 38.Tricco A. C., Lillie E., Zarin W., et al. PRISMA extension for scoping reviews (PRISMA-ScR): checklist and explanation. Annals of Internal Medicine . 2018;169(7):467–473. doi: 10.7326/M18-0850. [DOI] [PubMed] [Google Scholar]
- 39.Maier M., Ballester B. R., Leiva Bañuelos N., Duarte Oller E., Verschure P. F. M. J. Adaptive conjunctive cognitive training (ACCT) in virtual reality for chronic stroke patients: a randomized controlled pilot trial. Journal of Neuroengineering and Rehabilitation . 2020;17(1):p. 42. doi: 10.1186/s12984-020-0652-3. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 40.Mokhtar M. M., Atteya M., Rawash M. Virtual reality Xbox 360 Kinect training for stroke patients with hemiplegia. Bioscience Research . 2019;16(1):672–676. [Google Scholar]
- 41.Foreman M. H., Engsberg J. R. A virtual reality tool for measuring and shaping trunk compensation for persons with stroke: design and initial feasibility testing. Journal of Rehabilitation and Assistive Technologies Engineering . 2019;6(6) doi: 10.1177/2055668318823673. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 42.Boone A. E., Wolf T. J., Engsberg J. R. Combining virtual reality motor rehabilitation with cognitive strategy use in chronic stroke. The American Journal of Occupational Therapy . 2019;73(4) doi: 10.5014/ajot.2019.030130. [DOI] [PubMed] [Google Scholar]
- 43.Aramaki A. L., Sampaio R. F., Cavalcanti A., Dutra F. C. M. S. E. Use of client-centered virtual reality in rehabilitation after stroke: a feasibility study. Arquivos de Neuro-Psiquiatria . 2019;77(9):622–631. doi: 10.1590/0004-282X20190103. [DOI] [PubMed] [Google Scholar]
- 44.Schaham N. G., Zeilig G., Weingarden H., Rand D. Game analysis and clinical use of the Xbox-Kinect for stroke rehabilitation. International Journal of Rehabilitation Research . 2018;41(4):323–330. doi: 10.1097/MRR.0000000000000302. [DOI] [PubMed] [Google Scholar]
- 45.Liao W.-w., McCombe Waller S., Whitall J. Kinect-based individualized upper extremity rehabilitation is effective and feasible for individuals with stroke using a transition from clinic to home protocol. Cogent Medicine . 2018;5(1, article 1428038) doi: 10.1080/2331205X.2018.1428038. [DOI] [Google Scholar]
- 46.Moldovan I., Tric L., Ursu R., et al. Virtual rehabilitation programme using the MIRA platform, Kinect and Leap motion sensors in an 81 years old patient with ischemic stroke. 2017 E-Health and Bioengineering Conference (EHB); 2017; Sinaia, Romania. pp. 325–328. [DOI] [Google Scholar]
- 47.Maier M., Bañuelos N. L., Ballester B. R., Duarte E., PFMJ V. Conjunctive rehabilitation of multiple cognitive domains for chronic stroke patients in virtual reality. International Conference on Rehabilitation Robotics (ICORR); 2017; London, UK. pp. 947–952. [DOI] [PubMed] [Google Scholar]
- 48.Lee H. C., Huang C. L., Ho S. H., Sung W. H. The effect of a virtual reality game intervention on balance for patients with stroke: a randomized controlled trial. Games for Health Journal . 2017;6(5):303–311. doi: 10.1089/g4h.2016.0109. [DOI] [PubMed] [Google Scholar]
- 49.Norouzi-Gheidari N., Hernandez A., Archambault P. S., Higgins J., Poissant L., Kairy D. Feasibility, Safety and efficacy of a virtual reality exergame system to supplement upper extremity rehabilitation post-stroke: a pilot randomized clinical trial and proof of principle. International Journal of Environmental Research and Public Health . 2019;17(1):p. 113. doi: 10.3390/ijerph17010113. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 50.Cano-Mañas M. J., Collado-Vázquez S., Rodríguez Hernández J., Muñoz Villena A. J., Cano-De-La-Cuerda R. Effects of video-game based therapy on balance, postural control, functionality, and quality of life of patients with subacute stroke: a randomized controlled trial. Journal of Healthcare Engineering . 2020;2020(13) doi: 10.1155/2020/5480315.5480315 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 51.Ho T. H., Yang F. C., Lin R. C., et al. Impact of virtual reality-based rehabilitation on functional outcomes in patients with acute stroke: a retrospective case-matched study. Journal of Neurology . 2019;266(3):589–597. doi: 10.1007/s00415-018-09171-2. [DOI] [PubMed] [Google Scholar]
- 52.Kim W. S., Cho S., Park S. H., Lee J. Y., Kwon S., Paik N. J. A low cost Kinect-based virtual rehabilitation system for inpatient rehabilitation of the upper limb in patients with subacute stroke. Medicine (Baltimore) . 2018;97(25, article e11173) doi: 10.1097/MD.0000000000011173. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 53.Ikbali Afsar S., Mirzayev I., Umit Yemisci O., Cosar Saracgil S. N. Virtual reality in upper extremity rehabilitation of stroke patients: a randomized controlled trial. Journal of Stroke and Cerebrovascular Diseases . 2018;27(12):3473–3478. doi: 10.1016/j.jstrokecerebrovasdis.2018.08.007. [DOI] [PubMed] [Google Scholar]
- 54.Grigoras A. V., Matei D., Ignat E. B. Non-immersive virtual reality for upper limb rehabilitation in stroke survivors - a feasibility study. Balneo Research Journal . 2018;9(3):232–239. doi: 10.12680/balneo.2018.187. [DOI] [Google Scholar]
- 55.Aşkın A., Atar E., Koçyiğit H., Tosun A. Effects of Kinect-based virtual reality game training on upper extremity motor recovery in chronic stroke. Somatosensory & Motor Research . 2018;35(1):25–32. doi: 10.1080/08990220.2018.1444599. [DOI] [PubMed] [Google Scholar]
- 56.Türkbey T. A., Kutlay S., Gök H. Clinical feasibility of Xbox Kinect TM training for stroke rehabilitation: a single-blind randomized controlled pilot study. Journal of Rehabilitation Medicine . 2017;49(1):p. 22. doi: 10.2340/16501977-2183. [DOI] [PubMed] [Google Scholar]
- 57.Park D. S., Lee D. G., Lee K., Lee G. Effects of virtual reality training using Xbox Kinect on motor function in stroke survivors: a preliminary study. Journal of Stroke and Cerebrovascular Diseases . 2017;26(10):2313–2319. doi: 10.1016/j.jstrokecerebrovasdis.2017.05.019. [DOI] [PubMed] [Google Scholar]
- 58.Shin J. H., Park S. B., Jang S. H. Effects of game-based virtual reality on health-related quality of life in chronic stroke patients: a randomized, controlled study. Computers in Biology and Medicine . 2015;63:92–98. doi: 10.1016/j.compbiomed.2015.03.011. [DOI] [PubMed] [Google Scholar]
- 59.Sin H., Lee G. Additional virtual reality training using Xbox Kinect in stroke survivors with hemiplegia. American Journal of Physical Medicine & Rehabilitation . 2013;92(10):871–880. doi: 10.1097/PHM.0b013e3182a38e40. [DOI] [PubMed] [Google Scholar]
- 60.Wiederhold B., Riva G. Balance recovery through virtual stepping exercises using Kinect skeleton tracking: a followup study with chronic stroke patients. Annual review of cybertherapy telemedicine: Advanced technologies in the Behavioral, Social Neurosciences . 2012;181:108–112. [Google Scholar]
- 61.Triandafilou K. M., Tsoupikova D., Barry A. J., Thielbar K. N., Stoykoy N., Kamper D. G. Development of a 3D, networked multi-user virtual reality environment for home therapy after stroke. Journal of Neuroengineering and Rehabilitation . 2018;15(1):p. 88. doi: 10.1186/s12984-018-0429-0. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 62.Tsoupikova D., Triandafilou K., Thielbar K., Rupp G., Preuss F., Kamper D. Multi-user virtual reality therapy for post-stroke hand rehabilitation at home. Journal of Systemics, Cybernetics and Informatics . 2015;14(2) [Google Scholar]
- 63.Held J. P., Ferrer B., Mainetti R., et al. Autonomous rehabilitation at stroke patients home for balance and gait: safety, usability and compliance of a virtual reality system. European Journal of Physical and Rehabilitation Medicine . 2018;54(4):545–553. doi: 10.23736/S1973-9087.17.04802-X. [DOI] [PubMed] [Google Scholar]
- 64.Lai C.-L., Tseng C.-M., Erdenetsogt D., Liao T.-K., Huang Y.-L., Chen Y.-F. A Kinect-based system for balance rehabilitation of stroke patients. IEICE Transactions on Information and Systems . 2016;E99.D(4):1032–1037. doi: 10.1587/transinf.2015CYP0016. [DOI] [Google Scholar]
- 65.Proffitt R., Lange B. Feasibility of a customized, in-home, game-based stroke exercise program using the Microsoft Kinect® sensor. International Journal of Telerehabilitation . 2015;7(2):p. 23. doi: 10.5195/ijt.2015.6177. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 66.Singh D. K. A., Nordin N. A. M., Abd Aziz N. A., Lim B. K., Soh L. C. Effects of substituting a portion of standard physiotherapy time with virtual reality games among community-dwelling stroke survivors. BMC Neurology . 2013;13(1):p. 199. doi: 10.1186/1471-2377-13-199. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 67.Shahmoradi L., Almasi S., Ahmadi H., et al. Virtual reality games for rehabilitation of upper extremities in stroke patients. Journal of Bodywork and Movement Therapies . 2021;26:113–122. doi: 10.1016/j.jbmt.2020.10.006. [DOI] [PubMed] [Google Scholar]
- 68.Sheehy L., Taillon-Hobson A., Sveistrup H., Bilodeau M., Yang C., Finestone H. Sitting balance exercise performed using virtual reality training on a stroke rehabilitation inpatient service: a randomized controlled study. PM & R : The Journal of Injury, Function, and Rehabilitation . 2020;12(8):754–765. doi: 10.1002/pmrj.12331. [DOI] [PubMed] [Google Scholar]
- 69.Al-Whaibi R. M., Al-Jadid M. S., ElSerougy H. R., Badawy W. M. Effectiveness of virtual reality-based rehabilitation versus conventional therapy on upper limb motor function of chronic stroke patients: a systematic review and meta-analysis of randomized controlled trials. Physiotherapy Theory and Practice . 2021;27:1–15. doi: 10.1080/09593985.2021.1941458. [DOI] [PubMed] [Google Scholar]
- 70.Peng Q. C., Yin L., Cao Y. Effectiveness of virtual reality in the rehabilitation of motor function of patients with subacute stroke: a meta-analysis. Frontiers in Neurology . 2021;12, article 639535 doi: 10.3389/fneur.2021.639535. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 71.Darekar A., McFadyen B. J., Lamontagne A., Fung J. Efficacy of virtual reality-based intervention on balance and mobility disorders post-stroke: a scoping review. Journal of Neuroengineering and Rehabilitation . 2015;12(1):p. 46. doi: 10.1186/s12984-015-0035-3. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 72.Cicerone K. D., Langenbahn D. M., Braden C., et al. Evidence-based cognitive rehabilitation: updated review of the literature from 2003 through 2008. Archives of Physical Medicine and Rehabilitation . 2011;92(4):519–530. doi: 10.1016/j.apmr.2010.11.015. [DOI] [PubMed] [Google Scholar]
- 73.Laver K. E., George S., Thomas S., Deutsch J. E., Crotty M. Virtual reality for stroke rehabilitation. Cochrane Database of Systematic Reviews . 2010;12(2) doi: 10.1002/14651858.CD008349. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 74.Pollock A., Baer G., Campbell P., et al. Physical rehabilitation approaches for the recovery of function and mobility following stroke. Stroke . 2014;45(10):p. e202. doi: 10.1002/14651858.CD001920.pub3. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 75.Thomson K., Pollock A., Bugge C., Brady M. Commercial gaming devices for stroke upper limb rehabilitation: a systematic review. International Journal of Stroke . 2014;9(4):479–488. doi: 10.1111/ijs.12263. [DOI] [PubMed] [Google Scholar]
- 76.Adomavičienė A., Daunoravičienė K., Kubilius R., Varžaitytė L., Raistenskis J. Influence of new technologies on post-stroke rehabilitation: a comparison of Armeo spring to the Kinect system. Medicina . 2019;55(4) doi: 10.3390/medicina55040098. [DOI] [PMC free article] [PubMed] [Google Scholar]
