Table 1:
Summary statistics of segmental duplications in T2T-CHM13 and GRCh38
| Assembly | Gbp | % SD | SD (Mbp) | # SDs | inter (Mbp) | # inter | intra (Mbp) | # intra | acro (Mbp) | # acro | peri (Mbp) | # peri | telo (Mbp) | # telo |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||||||
| T2T CHM13 v1.0* | 3.114 | 6.665 | 207.563 | 41289 | 121.113 | 30484 | 142.958 | 10805 | 35.106 | 13264 | 88.606 | 24985 | 10.975 | 4998 |
| GRCh38 | 3.114 | 5.372 | 167.297 | 24280 | 83.556 | 16348 | 120.710 | 7932 | 6.624 | 1407 | 53.944 | 10606 | 8.926 | 1529 |
| Difference | 0.000 | 1.293 | 40.266 | 17009 | 37.556 | 14136 | 22.248 | 2873 | 28.482 | 11857 | 34.662 | 14379 | 2.049 | 3469 |
| previously unresolved or structurally variable | 0.240 | 33.885 | 81.338 | 25161 | 61.873 | 20579 | 54.932 | 4582 | 35.039 | 13258 | 54.037 | 19607 | 5.616 | 4005 |
| T2T CHM13 v1.0* + rDNA estimate | 3.114 | 6.987 | 217.598 | 66042 | 131.148 | 49213 | 152.993 | 16829 | 45.141 | 38017 | 98.641 | 49738 | 10.975 | 4998 |
*
The version of T2T-CHM13 v1.0 used included chrY from GRCh38
Mbp: the number of nonredundant Mbp of SD; peri: within 5 Mbp of the heterochromatin surrounding the centromere; telo: within 500 kbp of the telomere; acro: within the short arms of the acrocentric chromosomes.
Difference: SD content difference between T2T-CHM13 v1.0 and GRCh38.
Previously unresolved or structurally variable: Sequence in T2T-CHM13 that does not have 1 Mbp of synteny with GRCh38.
GRCh38 contains 149,690,719 of gap sequence included in the reported # of Gbp.