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. 2022 Apr 8;13:154. doi: 10.1186/s13287-022-02841-z

Retraction Note: BMP2 secretion from hepatocellular carcinoma cell HepG2 enhances angiogenesis and tumor growth in endothelial cells via activation of the MAPK/p38 signaling pathway

Peng-Cheng Feng 1, Xing-Fei Ke 1, Hui-Lan Kuang 1, Li-Li Pan 1, Qiang Ye 1, Jian-Bing Wu 1,
PMCID: PMC8994218  PMID: 35395807

Retraction Note: Stem Cell Research & Therapy (2019) 10:237 https://doi.org/10.1186/s13287-019-1301-2

The Editors-in-chief have retracted this article. After publication, concerns were raised regarding the validity of the presented data.

Specifically:

  • Duplicated images are presented in Fig. 3g (H_shNC) and Fig. 7g (H-oeBMP2 + SB-239063);

  • Duplicated images are presented in Fig. 4d (H_shNC) and Fig. 6d (H_oeBMP2 + SB-239063);

  • Breaks appear to be present in the western blot backgrounds in Fig. 5a p-ERK1/2, p-JNK and JNK images, and the authors have been unable to provide the underlying raw data to address this;

  • One of the tumor images in Fig. 3b (H_oeBMP2) appears highly similar to that presented in Fig. 7a (shALX4) in [1].

The Editors-in-Chief therefore no longer have confidence in the presented data and the conclusions drawn.

The authors have not responded to correspondence from the editor or publisher about this retraction.

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Reference

  • 1.Zhao X, Hu X. Downregulated long noncoding RNA LINC00313 inhibits the epithelial-mesenchymal transition, invasion, and migration of thyroid cancer cells through inhibiting the methylation of ALX4. J Cell Physiol. 2019;234(11):20992–21004. doi: 10.1002/jcp.28703. [DOI] [PubMed] [Google Scholar]

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