Figure 5.

Cardiac magnetic resonance features and histopathological findings of structural changes in myocarditis and ALVC. Myocarditis (A and B): postcontrast T1 inversion recovery sequence in short-axis view showing subepicardial LGE of the inferolateral LV wall (arrows) (A); corresponding panoramic histopathological view of the inferolateral LV wall showing extensive fibrous tissue replacement in the subepicardial layer of the myocardium (B). Desmosomal gene-related ALVC in a sudden cardiac death victim carrying a DSP mutation (C and D): postcontrast T1 inversion recovery sequence in short-axis view showing subepicardial LGE of the inferolateral LV wall (arrows) in a DSP gene mutation carrier (C). Panoramic histopathological view showing fibrofatty myocardial replacement of the outer layer of the inferolateral LV wall (D). Modified from Corrado et al. ¹³ ALVC, arrhythmogenic left ventricular cardiomyopathy; LGE, late gadolinium enhancement; LV, left ventricle.