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. 2022 Apr 11;40(4):438. doi: 10.1016/j.ccell.2022.03.010

Immune responses following third COVID-19 vaccination are reduced in patients with hematological malignancies compared to patients with solid cancer

Annika Fendler, Scott TC Shepherd, Lewis Au, Katalin A Wilkinson, Mary Wu, Andreas M Schmitt, Zayd Tippu, Sheima Farag, Aljosja Rogiers, Ruth Harvey, Eleanor Carlyle, Kim Edmonds, Lyra Del Rosario, Karla Lingard, Mary Mangwende, Lucy Holt, Hamid Ahmod, Justine Korteweg, Tara Foley, Taja Barber, Andrea Emslie-Henry, Niamh Caulfield-Lynch, Fiona Byrne, Benjamin Shum, Camille L Gerard, Daqi Deng, Svend Kjaer, Ok-Ryul Song, Christophe Queval, Caitlin Kavanagh, Emma C Wall, Edward J Carr, Sina Namjou, Simon Caidan, Mike Gavrielides, James I MacRae, Gavin Kelly, Kema Peat, Denise Kelly, Aida Murra, Kayleigh Kelly, Molly O’Flaherty, Robyn L Shea, Gail Gardner, Darren Murray, Sanjay Popat, Nadia Yousaf, Shaman Jhanji, Nicholas Van As, Kate Young, Andrew JS Furness, Lisa Pickering, Rupert Beale, Charles Swanton; Crick COVID19 consortium, Sonia Gandhi, Steve Gamblin, David LV Bauer, George Kassiotis, Michael Howell, Emma Nicholson, Susanna Walker, Robert J Wilkinson, James Larkin, Samra Turajlic ; CAPTURE consortium
PMCID: PMC8996376  PMID: 35413273

Main Text

(Cancer Cell 40, 114–116; February 14, 2022)

In this report from the CAPTURE study (NCT03226886), we demonstrate that a third dose of COVID-19 vaccine boosts neutralizing antibody (NAb) and cellular responses in patients with cancer, including those that had undetectable NAb titers (NAbT) following two vaccine doses or for whom NAbT waned. We have noted that one key member of the CAPTURE consortium—Sanjay Popat—was inadvertently not included in the author list. We now include him as a co-author. There are no additional changes to the declaration of interests statement, since Dr. Popat declares no competing conflict of interest. This author list change is now reflected in the online version of this letter.


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