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. 2022 Mar 23;11(7):1076. doi: 10.3390/cells11071076

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The effect of stevioside on the histological examination of the epididymal adipose tissue of C57BL/6 mice and db/db mice. (a) Paraffin sections of epididymal adipose tissue of mice treated with stevioside or vehicle were stained with H&E. Scale bar indicates 100 µm. (b) The average adipocyte size of epididymal adipose tissue in mice. (c) The weight of epididymal fat in mice. C57BL/6; negative control group that received saline, db/db; control group that received saline, db/db_SS; control group that received 40 mg/kg of stevioside. All data are presented as mean ± SD, and tests were performed in three independent experiments. ** p < 0.01, *** p < 0.001 and **** p < 0.0001.