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CRABP1-MAPK signalsome. The action of CRABP1-signalsome in growth-factor stimulated MAPK activity is mediated by its direct competition with Ras, resulting in dampened MAPK activation. CRABP1: Cellular Retinoic Acid Binding Protein 1, RA: retinoic acid, RAF: rapidly Accelerated Fibrosarcoma, MEK: mitogen-activated protein kinase kinase, ERK: extracellular-signal-regulated kinase.
