Table 2. The result about whether the brain was optimized as the schizophrenia-associated tissue based on each brain region’s gene/isoform-level eQTLs.
Table 2—source data 1. Tissue significance estimated by eDESE:dist based on the gene-level expression profiles.
elife-70779-table2-data1.xlsx (11.2KB, xlsx)
Table 2—source data 2. Tissue significance estimated by eDESE:dist based on the isoform-level expression profiles.
elife-70779-table2-data2.xlsx (10.6KB, xlsx)
Table 2—source data 3. Tissue significance estimated by eDESE:gene based on the gene-level eQTLs of each brain region.
elife-70779-table2-data3.xlsx (30.8KB, xlsx)
Table 2—source data 4. Tissue significance estimated by eDESE:isoform based on the isoform-level eQTLs of each brain region.
elife-70779-table2-data4.xlsx (30.2KB, xlsx)
| Brain regions | Gene-level eQTL | Isoform-level eQTL |
|---|---|---|
| Brain-Anterior cingulate cortex (BA24) | Yes | Yes |
| Brain-Cerebellum | Yes | Yes |
| Brain-Frontal Cortex (BA9) | Yes | Yes |
| Brain-Hippocampus | Yes | Yes |
| Brain-Spinal cord (cervical c-1) | Yes | Yes |
| Brain-Amygdala | Yes | No |
| Brain-Caudate (basal ganglia) | Yes | No |
| Brain-Cerebellar Hemisphere | Yes | No |
| Brain-Cortex | Yes | No |
| Brain-Hypothalamus | Yes | No |
| Brain-Nucleus accumbens (basal ganglia) | Yes | No |
| Brain-Putamen (basal ganglia) | No | No |
| Brain-Substantia nigra | Yes | No |
“Yes” denotes that brain (i.e., all thirteen brain tissues) was estimated as the significantly schizophrenia-associated tissue based on the gene/isoform-level eQTLs of the tissue. “No” denotes the contrary. The font names of the optimized brain regions are bold. See also Table 2—source data 1, Table 2—source data 2, Table 2—source data 3 and Table 2—source data 4.