Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains

Following a review of this article, under the terms of NIH grant number U01NS110438 it was determined that a change of authorship was appropriate. The author list previously omitted Dr. Mukesh Kumar, Dr. Hendrik Wesseling, and Dr. Judith A. Steen. In addition, Dr. Nicholas T. Seyfried and Dr. Judith A. Steen should have been included as co-corresponding authors. The author list, author contributions, and acknowledgements have now been corrected online to reflect these changes, and the authors apologize for any confusion this adjustment may have caused.

We have also become aware of the following typographical errors. (1) In Figures 3 and S4, the accompanying legends, the Figure S7 legend, and throughout the text, “trimethylation” should read “methylation.” (2) In Figures 3 and S4, Serine 289 should be phosphorylated, not Serine 293, consistent with Table S3. (3) In Figure S2, the x axis tick marks in (C) and (D) should be in increments of 0.05. These errors have also been corrected online.

Figure 3.

PTMs of Tau Filaments from CBD and AD Detected by MS (Original)

Figure S4.

MS of Tau in CBD and AD Showing PTMs of the 2N4R Isoform (Original)

Figure 3.

PTMs of Tau Filaments from CBD and AD Detected by MS (Corrected)

Figure S4.

MS of Tau in CBD and AD Showing PTMs of the 2N4R Isoform (Corrected)

Figure S2.

Resolution of Cryo-EM Singlet and Doublet Fibril Maps in CBD (Original)

Figure S2.

Resolution of Cryo-EM Singlet and Doublet Fibril Maps in CBD (Corrected)