Due to a production error in Table 1 of this Full Paper, the chemical structure of compound 5 a (Entry 1) was erroneously repeated for Entry 2. Each subsequent structure was thus shifted one row down. The correct Table 1 appears below.
Table 1.
Antiviral properties of the tested compounds against SARS‐CoV‐2.
|
Entry |
Compd. |
IC50 [mM][a] |
CC50 [mM][b] |
SI[c] |
|---|---|---|---|---|
|
1 |
|
12.223 |
4.098 |
0.335 |
|
2 |
|
1.150 |
1.961 |
1.705 |
|
3 |
|
2.718 |
3.431 |
1.262 |
|
4 |
|
0.120 |
0.378 |
3.150 |
|
5 |
|
0.477 |
4.916 |
10.306 |
|
6 |
|
0.952 |
3.508 |
3.685 |
|
7 |
|
1.079 |
2.308 |
2.139 |
|
8 |
|
0.2064 |
0.4088 |
1.981 |
|
9 |
|
0 |
1.906 |
— |
|
10 |
|
3.082 |
2.827 |
0.917 |
|
11 |
|
5.659 |
3.381 |
0.597 |
|
12 |
|
1.837 |
1.429 |
0.778 |
|
13 |
|
1.687 |
2.200 |
1.304 |
|
14 |
|
3.975 |
3.577 |
0.900 |
|
15 |
|
2.993 |
1.142 |
0.382 |
|
16 |
|
0.3638 |
1.396 |
3.837 |
|
17 |
|
2.982 |
3.406 |
1.142 |
|
18 |
|
2.340 |
3.609 |
1.542 |
|
19 |
|
7.956 |
2.236 |
0.281 |
|
20 |
|
1.382 |
5.262 |
3.808 |
[a] CC50 = Cytotoxic concentration of the tested agent to elicit 50% cell growth relative to control. [b] IC50 = Inhibitory concentration of the tested agent to elicit 50% cell growth relative to control. [c] Selectivity index/therapeutic index = CC50/IC50.
