Figure 4.
Proposed model for the antiviral mechanism of molnupiravir based on β-d-N4-hydroxycytidine (NHC)-induced mutagenesis and the inhibition of RNA synthesis. Tautomeric forms and the base pairing of NHC are shown in the lower-left panel. Illustration based on the experimental data reported by Gordon et al. [136] and Kabinger et al. [137], and adapted from ref. [146].