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. 2022 Apr 11;14(4):840. doi: 10.3390/pharmaceutics14040840

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Stability and hemolysis of CaF₂:Y,Gd,Nd NPs. (a) Size and (b) zeta potential of CaF₂:Y,Gd,Nd NPs in 50% FCS; (c) hemolysis of CaF₂:Y,Gd,Nd NPs after incubation with red blood cells at various concentrations (0−1 mg/mL) for 4 h; (d) hemolysis image after centrifugation. All experiments were conducted in three independent experiments and data are expressed as mean ± SD. Statistical significance was calculated by comparing the experimental group with the control group using one-way ANOVA (**** p < 0.0001).