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. 2022 Apr 16;12(4):587. doi: 10.3390/biom12040587

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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N-cadherin upregulation in FD. (a) Positive control for N-cadherin staining in oral epithelium. (b) N-cadherin staining in epithelium of developmental odontogenic cyst and surrounding remodeling bone. (c) N-cadherin over-expression in osteoblasts lining osteoid in a case of pagetoid-type FD. (d) Magnification of osteoblasts expressing N-cadherin in FD. (e) A case of FD showing N-cadherin selectively expressed in osteoblasts without any expression in fibroblastoid cells. (f) A case of FD showing N-cadherin over-expression in fibroblastoid cells committed to inefficient osteoblast differentiation. Magnifications, ×4 (b,c), ×10 (e,f), ×20 (a,d).