Table 1.
Clinical trials for cancer gene therapy.
| Disease | Vector/Gene | Phase | Status | Company | Identifier |
|---|---|---|---|---|---|
| Ovarian Cancer and Peritoneal Cavity Cancer | Ad5CMV-p53 gene | I | Completed | University of Texas Southwestern Medical Center | NCT00003450 |
| Pancreatic cancer | Rexin-gene | I | Completed | Epeius Biotechnologies | NCT00121745 |
| Prostate cancer | Ad5-yCD/mutTKSR39rep-hIL12 | I | Unknown | Henry Ford Health System Detroit | NCT02555397 |
| Non-Small Cell Lung Cancer | AdV-IL-12 | I | Incomplete | Houston Methodist Cancer Center | NCT04911166 |
| Triple-Negative Breast Cancer | AdV-IL-12 | II | Incomplete | Houston Methodist Cancer Center | NCT04095689 |
| Breast Cancer | Ad5CMV-p53 gene | I | Completed | Fox Chase Cancer Center Philadelphia | NCT00004038 |
| Ovarian Cancer and Primary Peritoneal Cancer | Ad5CMV-p53 | I | Completed | Simmons Cancer Center—Dallas | NCT00003450 |
| Prostate Cancer | Ad5-CMV-NIS | I | Completed | Mayo Clinic Rochester | NCT00788307 |