Skip to main content
The British Journal of General Practice logoLink to The British Journal of General Practice
. 2022 Apr 20;72(720):e501–e510. doi: 10.3399/BJGP.2021.0691

Psychological impact of the COVID-19 pandemic on primary care workers: a cross-sectional study

Enric Aragonès 1, Isabel del Cura-González 2, Lucía Hernández-Rivas 3, Elena Polentinos-Castro 4, Maria Isabel Fernández-San-Martín 5, Juan A López-Rodríguez 6, Josep M Molina-Aragonés 7, Franco Amigo 8, Itxaso Alayo 9, Philippe Mortier 10, Montse Ferrer 11, Víctor Pérez-Solà 12, Gemma Vilagut 13, Jordi Alonso 14; the MINDCOVID-19 research group
PMCID: PMC9037185  PMID: 35440468

Abstract

Background

The COVID-19 pandemic has had a major impact on the mental health of healthcare workers, yet studies in primary care workers are scarce.

Aim

To investigate the prevalence of and associated factors for psychological distress in primary care workers during the first COVID-19 outbreak.

Design and setting

This was a multicentre, cross-sectional, web-based survey conducted in primary healthcare workers in Spain, between May and September 2020.

Method

Healthcare workers were invited to complete a survey to evaluate sociodemographic and work-related characteristics, COVID-19 infection status, exposure to patients with COVID-19, and resilience (using the Connor–Davidson Resilience Scale), in addition to being screened for common mental disorders (depression, anxiety disorders, post-traumatic stress disorder, panic attacks, and substance use disorder). Positive screening for any of these disorders was analysed globally using the term ‘any current mental disorder’.

Results

A total of 2928 primary care professionals participated in the survey. Of them, 43.7% (95% confidence interval [CI] = 41.9 to 45.4) tested positive for a current mental disorder. Female sex (odds ratio [OR] 1.61, 95% CI = 1.25 to 2.06), having previous mental disorders (OR 2.58, 95% CI = 2.15 to 3.10), greater occupational exposure to patients with COVID-19 (OR 2.63, 95% CI = 1.98 to 3.51), having children or dependents (OR 1.35, 95% CI = 1.04 to 1.76 and OR 1.59, 95% CI = 1.20 to 2.11, respectively), or having an administrative job (OR 2.24, 95% CI = 1.66 to 3.03) were associated with a higher risk of any current mental disorder. Personal resilience was shown to be a protective factor.

Conclusion

Almost half of primary care workers showed significant psychological distress. Strategies to support the mental health of primary care workers are necessary, including designing psychological support and resilience-building interventions based on risk factors identified.

Keywords: COVID-19 pandemic, cross-sectional study, health personnel, mental health, primary health care, psychological resilience

INTRODUCTION

The outbreak of the COVID-19 pandemic in March 2020 saturated the capacity of the Spanish healthcare system and forced organisational changes at all levels of care to adapt to the changing conditions.1 There was an important and abrupt change in the working conditions of primary care staff to meet new requirements, with staff having to tolerate uncertainties, organisational shortcomings, and a shortage of protective equipment.2 In Spain, primary care was responsible for the screening and diagnosis of patients with COVID-19, non-hospital treatment of most of the patients with COVID-19, and, in the initial moments of the collapse of the healthcare system, even complex home care for patients with COVID-19. Many primary care professionals took on occupational relocations and new tasks, such as working in nursing homes, COVID-19-specific field hospitals, and also relocations to hospital services.3,4

Overload and changes in working conditions, facing new and unfamiliar situations, lack of resources, fear of contagion, or fear of infecting family members generated significant stress in healthcare professionals. An increase in the prevalence of depression, anxiety, post-traumatic stress, drugs use, burnout, and increased risk of suicide have been described.57 Importantly, the psychological distress affecting healthcare workers not only has an impact on their wellbeing, but also their professional performance, quality of care, and patient safety.8 On the other hand, a sense of professional and civic responsibility has emerged in healthcare professionals,9,10 and staff have shown resilience in the face of insecurity and difficulties.

How this fits in

In the context of the COVID-19 pandemic, a psychological impact on healthcare workers has been described, although studies in non-hospital settings are scarce. This study found that a high proportion of primary care workers (43.7%) had a current mental disorder. Female sex, having a history of previous mental disorders, greater work exposure to patients with COVID-19, having children or dependents, and certain professional positions were associated with greater risk. Personal resilience was shown to be a protective factor. Preventive and support interventions for the mental health of primary care workers are required.

Despite the abundant literature on this subject, few studies have specifically analysed the situation in primary care,1115 notwithstanding the repercussions for those working in these settings and the different characteristics and conditions compared with those reported in hospital settings. In addition, females constitute the largest group within healthcare professions and yet most studies on the psychological impact of the pandemic on healthcare workers rarely mention sex as a variable affecting the results and they have not provided disaggregated data.16 This study therefore analysed the psychological distress experienced by primary care workers in the context of the COVID-19 pandemic, including a sex-disaggregated analysis.

The aim was to investigate psychological distress in Spanish primary care workers during the first COVID-19 outbreak period. Specifically, this study aimed to:

  • estimate the prevalence of psychological distress by sex;

  • evaluate the associations between psychological distress and sociodemographic, occupational, and health characteristics by sex; and

  • explore the role of resilience as a protective factor.

METHOD

Design, population, and sampling

A multicentre, cross-sectional, web-based self-reported survey was conducted of Spanish healthcare workers between May and September of 2020 as part of the MINDCOVID-19 project.17 All workers in each healthcare institution included were invited to participate using administrative email distribution lists (that is, census sampling) that generated invitations to participate in the study containing an anonymous link to access the survey. A detailed description of the methods and procedures can be found in a previous article.6 The present study analysed the data obtained from professionals in the primary care settings of five autonomous communities in Spain (the Basque Country, Catalonia, Madrid, Castile and León, and Valencian Community). The staff in Spanish primary care centres comprise family doctors, paediatricians, dentists, nurses, auxiliary nurses, midwives, social workers, administrative staff, and other personnel.18

Measurements

Sociodemographic and occupational characteristics

The survey included personal characteristics such as sex, age, marital status, having dependent children, caring for an older person or someone with disabilities, and profession.

Mental disorders

The survey screened for the following mental disorders: major depressive disorder, evaluated with the eight-item Patient Health Questionnaire;19,20 generalised anxiety disorder, evaluated with the seven-item Generalized Anxiety Disorder scale;21,22 panic attacks, evaluated via an item from the World Mental Health-International College Student;23,24 post-traumatic stress disorder (PTSD), evaluated with the PTSD Checklist for DSM-5;25 and substance use disorder, evaluated via the CAGE-AID questionnaire.26,27

The main variable, the presence of psychological distress, was considered present when there was a current positive screening for any of the above-mentioned mental disorders.

Mental disorders before the onset of the COVID-19 outbreak were recorded using a self-reported checklist based on the Composite International Diagnostic Interview, including lifetime depressive disorder, bipolar disorder, anxiety disorder, panic attacks, alcohol and drug use disorders, and other mental disorders.28,29

COVID-19 exposure and infection status

Participants were questioned about having been infected with SARS-CoV-2 and whether or not admission to hospital was necessary. Additionally, the responders were asked if their close ones (partner, children, parents, other relatives, or close friends) had contracted COVID-19. Occupational exposure to patients with COVID-19 was assessed using a five-level Likert scale (ranging from none of the time to all of the time).

Resilience

The 10-item Connor–Davidson Resilience Scale (CD-RISC-10)30,31 is a self-administered questionnaire with items rated on a five-point Likert scale (from 0, completely disagree to 4, completely agree) so that higher total scores indicate greater resilience.

Ethical considerations

Before accessing the survey content, participants were informed about the objectives and procedures of the study, and their explicit consent for participation was obtained. The study was registered at ClinicalTrials.gov (reference: NCT04556565). As psychological distress could be revealed in the survey, participants were offered a list of local resources for mental health care.

Statistical analysis

Participants who completed all the mental health items were included in the analysis. Sociodemographic, occupational, and health characteristics were compared between responders with and without psychological distress (that is, participants with and without a positive screening for any current mental disorder). To explore resilience, these variables were compared between participants with a resilience score above and below the 25th percentile. Categorical variables were analysed using the χ2-test, and the Mann–Whitney U-test was used for continuous variables.

A multivariable logistic regression model was estimated to assess potential factors associated with any current mental disorder. As the psychological impact of the pandemic can vary over time, the analyses were adjusted by the month of the response to the survey. A sex-stratified analysis was also conducted.

Statistical analyses were conducted using Stata (version 14). Statistical significance was set at P<0.05.

RESULTS

Response

A total of 3089 primary care professionals participated in the survey. Of these, 155 were excluded because of missing data in the questionnaires regarding mental health and six because of a lack of information on sex. Finally, 2928 participants were included in the statistical analysis.

The survey response rate was 12.5% in the main study when including all healthcare settings. The value for the primary care setting alone could not be calculated because the censuses of some of the participating centres include both primary care and hospital professionals.

Participant characteristics

Table 1 shows participant characteristics, COVID-19 exposure, and infection status, as well as lifetime mental disorders. Of the participating sample, 82.7% were female and the median age was 50 years (interquartile range 42–57). Most responders were physicians (47.9%), followed by nurses and auxiliary nurses (29.8%), and administrative staff (11.1%). Of all participants, 41.6% reported any lifetime mental disorder before the COVID-19 outbreak.

Table 1.

Sociodemographic and occupational characteristics, COVID-19 exposure, infection status, and lifetime mental disorders in primary healthcare workers

Characteristic Total (n = 2928),a n (%) Male (n = 506),a n (%) Female (n = 2422),a n (%) P-valueb
Age, years 2928 506 2422 <0.001
  18–29 207 (7.1) 27 (5.3) 180 (7.4)
  30–49 1185 (40.5) 166 (32.8) 1019 (42.1)
  ≥50 1536 (52.5) 313 (61.9) 1223 (50.5)

Marital statusc 2923 505 2418 0.025
  Single, divorced/separated, or widowed 1166 (39.9) 179 (35.4) 987 (40.8)
  Married 1757 (60.1) 326 (64.6) 1431 (59.2)

Children in carec 2840 493 2347 0.068
  Aged ≤12 years 752 (26.5) 110 (22.3) 642 (27.4)
  Aged >12 years 516 (18.2) 93 (18.9) 423 (18.0)
  None 1572 (55.4) 290 (58.8) 1282 (54.6)

Caring for older person or person with disabilities 2464 420 2044 0.003
  Yes 336 (13.6) 38 (9.0) 298 (14.6)
  No 2128 (86.4) 382 (91.0) 1746 (85.4)

Profession 2892 500 2392 <0.001
  Physician 1384 (47.9) 298 (59.6) 1086 (45.4)
  Nurse or auxiliary nurse 863 (29.8) 85 (17.0) 778 (32.5)
  Administrative staff 322 (11.1) 54 (10.8) 268 (11.2)
  Other staff involved in patient care 228 (7.9) 34 (6.8) 194 (8.1)
  Other staff not involved in patient care 95 (3.3) 29 (5.8) 66 (2.8)

Frequency of direct exposure to patients with COVID-19 2846 496 2350 0.015
  All/most of the time 1357 (47.7) 238 (48.0) 1119 (47.6)
  Some of the time 1041 (36.6) 161 (32.5) 880 (37.4)
  A little/none of the time 448 (15.7) 97 (19.6) 351 (14.9)

Close one infected with COVID-19 2926 506 2420 0.502
  No 542 (18.5) 103 (20.4) 439 (18.1)
  Close one infected, not family member 1721 (58.8) 292 (57.7) 1429 (59.0)
  Family member infected 663 (22.7) 111 (21.9) 552 (22.8)

COVID-19 infection status 2923 505 2418 0.053
  Admission to hospital 39 (1.3) 12 (2.4) 27 (1.1)
  Test positive/diagnosed 548 (18.7) 101 (20.0) 447 (18.5)
  None 2336 (79.9) 392 (77.6) 1944 (80.4)

Resilience score, CD-RISC-10, median (IQR)c 29.0 (25.0–33.0) 30.0 (26.0–35.0) 29.0 (24.0–33.0) <0.001

Lifetime mental disorders before COVID-19 outbreak 2895 501 2394 0.070
  Yes 1203 (41.6) 190 (37.9) 1013 (42.3)
  No 1692 (58.4) 311 (62.1) 1381 (57.7)
a

Unless stated otherwise.

b

Mann–Whitney U-test for continuous variables and χ2-test for categorical variables.

c

Total, n = 2744; males, n = 485; and females, n = 2259. CD-RISC-10 = 10-item Connor–Davidson Resilience Scale. Close one = partner, children, parents, other relatives, or close friends. IQR = interquartile range.

Prevalence of any current mental disorder

The global prevalence of a positive screening for any current mental disorder was 43.7% (95% confidence interval [CI] = 41.9 to 45.4). The prevalence was significantly lower for males (33.8%, 95% CI = 29.7 to 37.9) than for females (45.7%, 95% CI = 43.7 to 47.7) (data not shown).

Factors associated with any current mental disorder

Table 2 shows the associations between the characteristics of participants and a positive screening for any current mental disorder, stratified by sex. Statistically significant differences in age and profession were found. Caring for people was associated with a higher prevalence of a current mental disorder in females, but these differences were not significant among males. The presence of a lifetime mental health disorder was associated with a positive screening for any current mental disorder.

Table 2.

Prevalence of positive screening for any current mental disorder according to the characteristics of primary care workers, disaggregated by sex

Characteristic Total (n = 1278) n (%)a P-value for χ2 Male (n = 171) n (%)a P-value for χ2 Female (n = 1107) n (%)a P-value for χ2
Age, years <0.001 0.003 <0.001
  18–29 99 (47.8) 7 (25.9) 92 (51.1)
  30–49 586 (49.5) 73 (44.0) 513 (50.3)
  ≥50 593 (38.6) 91 (29.1) 502 (41.0)

Marital status 0.04 0.085 0.18
  Single, divorced/separated, or widow/er 537 (46.1) 69 (38.5) 468 (47.4)
  Married 740 (42.1) 101 (31.0) 639 (44.7)

Children in care 0.02 0.628 0.03
  Aged ≤12 years 362 (48.1) 40 (36.4) 322 (50.2)
  Aged >12 years 222 (43.0) 28 (30.1) 194 (45.9)
  None 659 (41.9) 100 (34.5) 559 (43.6)

Caring for older person or person with disabilities 0.003 0.62 0.009
  Yes 170 (50.6) 13 (34.2) 157 (52.7)
  No 894 (42.0) 116 (30.4) 778 (44.6)

Profession <0.001 0.005 <0.001
  Physician 544 (39.3) 84 (28.2) 460 (42.4)
  Nurse or auxiliary nurse 403 (46.7) 34 (40.0) 369 (47.4)
  Administrative staff 179 (55.6) 27 (50.0) 152 (56.7)
  Other staff involved in patient care 90 (39.5) 11 (32.4) 79 (40.7)
  Other staff NOT involving patient care 47 (49.5) 14 (48.3) 33 (50.0)

Frequency of direct exposure to patients with COVID-19 <0.001 0.33 <0.001
  All/most of the time 665 (49.0) 88 (37.0) 577 (51.6)
  Some of the time 436 (41.9) 48 (29.8) 388 (44.1)
  A little/none of the time 145 (32.4) 33 (34.0) 112 (31.9)

Close one infected with COVID-19 0.35 0.47 0.12
  No 241 (44.5) 30 (29.1) 211 (48.1)
  Close one infected, not family member 763 (44.3) 100 (34.2) 663 (46.4)
  Family member infected 273 (41.2) 41 (36.9) 232 (42.0)

COVID-19 infection status 0.06 0.18 0.14
  Admission to hospital 24 (61.5) 7 (58.3) 17 (63.0)
  Positive test/diagnosis 246 (44.9) 35 (34.7) 211 (47.2)
  None 1007 (43.1) 129 (32.9) 878 (45.2)

Lifetime mental disorders before COVID-19 outbreak <0.001 <0.001 <0.001
  Yes 712 (59.2) 93 (48.9) 619 (61.1)
  No 558 (33.0) 77 (24.8) 481 (34.8)
a

Percentages calculated from responders for each cell in Table 1. Close one = partner, children, parents, other relatives, or close friends.

Resilience

Resilience was associated with sex, profession, and lifetime mental health disorders (Table 3). Lower resilience was observed in females, administrative staff, responders with former mental health disorders, and those who declared being treated for such disorders.

Table 3.

Associations of sociodemographic and job characteristics, and lifetime mental health disorders with resilience in primary healthcare workers

Characteristic Resilience score, CD-RISC-10

Under 25th percentile (n = 660), n (%) Over 25th percentile (n = 2084), n (%) P-valuea
Sex 0.003
  Male 91 (18.8) 394 (81.2)
  Female 569 (25.2) 1690 (74.8)

Age, years 0.23
  18–29 49 (25.8) 141 (74.2)
  30–49 285 (25.5) 834 (74.5)
  ≥50 326 (22.7) 1109 (77.3)

Marital status 0.99
  Single, divorced/separated or widowed 262 (24.1) 826 (75.9)
  Married 398 (24.1) 1254 (75.9)

Children in care 0.298
  Aged ≤12 years 167 (22.9) 563 (77.1)
  Aged >12 years 111 (22.3) 387 (77.7)
  None 382 (25.2) 1134 (74.8)

Caring for older person or person with disabilities 0.57
  Yes 74 (22.9) 249 (77.1)
  No 502 (24.4) 1559 (75.6)

Profession 0.008
  Physician 313 (23.7) 1008 (76.3)
  Nurse or auxiliary nurse 206 (25.4) 604 (74.6)
  Administrative staff 87 (29.0) 213 (71.0)
  Other profession involved in patient care 36 (16.4) 183 (83.6)
  Other staff NOT involved in patient care 16 (18.0) 73 (82.0)

Frequency of direct exposure to patients with COVID-19
  All/most of the time 298 (22.8) 1007 (77.2) 0.34
  Some of the time 253 (25.4) 743 (74.6)
  A little/none of the time 109 (24.8) 331 (75.2)

Close one infected with COVID-19 0.05
  No 142 (28.0) 366 (72.0)
  Close one infected, not family member 365 (22.6) 1249 (77.4)
  Family member infected 153 (24.7) 467 (75.3)

COVID-19 infection status 0.10
  Admission to hospital 11 (31.4) 24 (68.6)
  Test positive/diagnosed 138 (27.1) 371 (72.9)
  None 509 (23.2) 1686 (76.8)

Lifetime mental disorders before COVID-19 outbreak <0.001
  Yes 370 (32.6) 764 (67.4)
  No 285 (18.0) 1296 (82.0)
a

Mann–Whitney U-test for continuous variables and χ2-test for categorical variables. CD-RISC-10 = 10-item Connor–Davidson Resilience Scale. Close one = partner, children, parents, other relatives, or close friends. IQR = interquartile range.

Models

Table 4 shows the multivariate analyses of the associations between any current mental disorder and the characteristics of the responders. Being aged 30–49 years, having children aged >12 years, caring for an older person or someone with disablities, being a nurse or auxiliary nurse, or administrative staff, and being exposed to patients with COVID-19 were associated with a higher risk of mental disorder, both for the complete sample and in females alone. However, these associations were not present in males. Having a history of any lifetime mental disorder was associated with a higher risk of a current mental disorder. Resilience was shown to be a protective factor for any current mental disorder.

Table 4.

Multivariate associations between primary care workers’ characteristics and lifetime mental disorders, stratified by sexa

Characteristic Total (n = 2355), OR (95% CI) P-value Male (n = 408), OR (95% CI) P-value Female (n = 1947), OR (95% CI) P-value
Sex
  Male Reference NA NA
  Female 1.61 (1.25 to 2.06) <0.001 NA NA

Age, years
  18–29 1.12 (0.75 to 1.66) 0.588 0.34 (0.09 to 1.35) 0.124 1.34 (0.87 to 2.05) 0.180
  30–49 1.50 (1.19 to 1.88) 0.001 1.30 (0.72 to 2.33) 0.387 1.53 (1.19 to 1.97) 0.001
  ≥50 Reference Reference Reference

Children in care
  None Reference Reference Reference
  Aged ≤12 years 1.18 (0.91 to 1.51) 0.209 1.19 (0.63 to 2.23) 0.597 1.21 (0.92 to 1.60) 0.176
  Aged >12 years 1.31 (1.03 to 1.67) 0.026 1.11 (0.60 to 2.03) 0.746 1.35 (1.04 to 1.76) 0.025

Caring for older person or person with disabilities 1.54 (1.18 to 2.00) 0.001 1.38 (0.62 to 3.06) 0.428 1.59 (1.20 to 2.11) 0.001

Profession
  Physician Reference Reference Reference
  Nurse or auxiliary nurse 1.34 (1.09 to 1.65) 0.006 1.49 (0.81 to 2.75) 0.204 1.33 (1.06 to 1.66) 0.012
  Administrative staff 2.24 (1.66 to 3.03) <0.001 1.69 (0.82 to 3.49) 0.157 2.39 (1.70 to 3.35) <0.001
  Other staff involved in patient care 1.08 (0.76 to 1.54) 0.660 1.18 (0.47 to 3.01) 0.723 1.09 (0.74 to 1.59) 0.668
  Other staff not involved in patient care 2.22 (1.30 to 3.81) 0.004 2.24 (0.76 to 6.58) 0.142 2.09 (1.12 to 3.88) 0.020

Frequency of direct exposure to patients with COVID-19
  A little/none of the time Reference Reference Reference
  Some of the time 1.88 (1.40 to 2.52) <0.001 1.15 (0.56 to 2.37) 0.712 2.06 (1.49 to 2.84) <0.001
  All/most of the time 2.63 (1.98 to 3.51) <0.001 1.61 (0.80 to 3.22) 0.183 2.90 (2.11 to 3.99) <0.001

Resilience score, CD-RISC-10 0.93 (0.92 to 0.95) <0.001 0.91 (0.88 to 0.95) <0.001 0.94 (0.92 to 0.95) <0.001

Any lifetime mental disorder 2.58 (2.15 to 3.10) <0.001 2.57 (1.60 to 4.12) <0.001 2.59 (2.12 to 3.16) <0.001
a

Exponentiated coefficients, adjusted by month of survey. Total model: pseudo-R2 0.1174; AIC 2874.2; BIC 2966.4; and AUC 0.72. Male model: pseudo-R2 0.1304; AIC 467.2; BIC 527.4; and AUC 0.74. Female model: pseudo-R2 0.1090; AIC 2422.4; BIC 2506.0; and AUC 0.71. AIC = Akaike Information Criterion. AUC = area under the curve. BIC = Bayesian Information Criterion. CD-RISC-10 = 10-item Connor–Davidson Resilience Scale. NA = Not applicable. OR = odds ratio.

DISCUSSION

Summary

The outcomes of the present study show that a high proportion (43.7%) of primary care workers screened positive for any current mental disorder; the proportion being significantly higher in females than in males. Female sex, having a previous history of mental disorders, greater occupational exposure to patients with COVID-19, caring for children or dependents, or certain occupations were factors that were independently associated with an increased risk of having a mental disorder, whereas resilience was shown to be a protective factor.

Strengths and limitations

This study is particularly relevant because it evaluated the impact of the pandemic on primary care professionals, whose work characteristics and pandemic-related experiences differ greatly from those of hospital workers, the latter being more widely studied in the scientific literature.32 A strength of this study is that other professional profiles aside from doctors or nurses were included; previous studies have rarely included this data. This allowed confirmation of the significant psychological repercussions of the pandemic on administrative personnel.

When interpreting these results, it should be kept in mind that females represent 83% of the participants, which, far from constituting a bias, is a reflection of the reality of the healthcare work setting, where females are the vast majority in all professional categories in European health systems and, in particular, in the Spanish health system.33,34 One of the strengths of the present analysis lies in the reporting of sex-disaggregated data.

This study has several limitations. First, participation was voluntary, which may have introduced a difficult-to-predict bias because of self-selection of participants in the survey.35 This is especially important when the non-response rate is high, although this limitation is inherent to the methodology employed and is similar to other studies based on telematic surveys.36 Second, in a cross-sectional study, causality cannot be inferred from the factors associated with the assessed outcomes. Observing the evolution over time of psychological distress as a function of experience with the pandemic will be necessary to establish causal relationships. Indeed, this is precisely the objective of a prospective follow-up of this cohort currently underway.6 Third, the presence of probable mental disorders has been assessed by a battery of screening instruments. Establishing genuine clinical diagnoses was not possible, but positive screenings can be a valid indicator of the presence of significant psychological distress.37,38 Finally, when interpreting the data from this cross-sectional study, the time at which they were obtained, between the end of the first wave and the beginning of the second wave in the pandemic epidemiological curve in Spain, must be considered.39

Comparison with existing literature

Differences in the prevalence of psychological distress by sex are to be expected, as a higher prevalence of mental disorders in females is a consistent finding in epidemiological studies.40,41 Greater vulnerability in females has also been reported among healthcare workers during the pandemic.4244 Various explanations for these differences have been proposed, including response bias (males would have greater difficulty recognising and communicating psychological distress), as well as biological, social, and demographic factors.45,46 This study found that having children aged >12 years or caring for an older person or person with disabilities are important risk factors for psychological distress in females, whereas this association was not observed in males. This suggests that different family roles may be a key factor in sex-related differences in emotional distress.16,47 In addition, differences in informal caregiving between sexes may have increased following the shutdown of or limited access to resources such as childcare centres, schools, daycare nursing centres, or residences for older people.48 A qualitative study involving healthcare workers in England shows caring responsibilities as a factor that affects males and females differently in terms of their emotional state during the pandemic.16

As expected, the greater the occupational exposure to patients with COVID-19, the greater the risk of psychological distress for the overall sample; an association that is stronger and more consistent in females than in males.49,50 However, similar to findings from other research,5153 this study found the paradox that administrative personnel were at greater risk than professional groups with direct patient contact. Again, these associations are strong and statistically significant in females, but not in males. As a result of the pandemic, primary care administrative staff have been exposed to changes, uncertainty, and a heavy workload, perhaps without sufficient support to handle this type of situation and with less control over their job conditions than other professional categories.54 In contrast, female doctors experienced less psychological distress than those in other occupations, possibly because of skills and experience in managing and coping with situations of complexity and uncertainty inherent to medical practice.55

The association between the existence of previous mental disorders and the current presence of any mental disorder was particularly strong, being comparable in both sexes. This was to be expected given the tendency for recurrence and the often chronic nature of mental disorders,56 and is consistent with other studies in healthcare workers in the pandemic setting.44,57 The relevance of this risk factor is accentuated by the fact that 42% of the individuals in the present sample reported a history of previous mental disorders.

Resilience is an individual’s ability to cope with and adapt to adverse situations while maintaining effective personal and professional functioning.58 Concurring with a study on healthcare workers in Italy,59 this work identified resilience as a protective factor against the psychological distress caused by the pandemic in healthcare professionals, both in males and females, although the level of resilience was higher among males.60 This ability to cope with stress was shown to be significantly impaired in those individuals with a previous history of mental disorders.

Implications for research and practice

This study found that a high proportion of primary healthcare workers experienced psychological distress in the context of the COVID-19 pandemic and some particularly vulnerable profiles were identified. Given this situation, establishing strategies and interventions for psychological support and resilience building of healthcare workers is highly relevant, taking into account the risk factors identified and tailoring the interventions accordingly. Proactive systems should be established to assess and monitor the psychological wellbeing of different professional groups in primary care and facilitate their access to psychological help.61 Additionally, interventions should be conducted to promote resilience, as it is a modifiable factor,62,63 implementing strategies focused on self-care and changes in the organisation and work environment.64,65

Longitudinal studies are necessary to assess the evolution of the psychological impact of the pandemic over time and to identify the factors that determine or can predict this evolution. Evaluating the usefulness, feasibility, and effectiveness of any preventive or therapeutic interventions under real conditions will also be important, as well as determining the best way to implement them.66

Acknowledgments

This study was possible thanks to the generous collaboration of all primary healthcare workers that participated in the survey in extremely busy times. The authors thank the researchers from all the healthcare institutions participating in the project who form the MINDCOVID-19 research group, listed in the Supplementary Appendix S1. The authors also thank Antonio González Herrera for his revision of the manuscript.

Funding

This work was funded by the Fondo de Investigación Sanitaria, Instituto de Salud Carlos III (Spanish Ministry of Science and Innovation) (reference: COV20/00711). The funders had no role in the study design, data collection, analyses, interpretation, preparation or review of the manuscript, or decision to submit the article for publication.

Ethical approval

Ethical approval was obtained from the Institutional Review Board Parc de Salut Mar (reference: 2020/9203/I), and by the relevant Institutional Review Boards of all the participating centres.

Data

The study database is available from the authors on reasonable request, following approval of a proposal and with a signed data-access agreement.

Provenance

Freely submitted; externally peer reviewed.

Competing interests

The authors have declared no competing interests.

Contributors

Gemma Vilagut and Jordi Alonso are joint senior authors. Details of the MINDCOVID-19 research group are provided in Supplementary Appendix S1.

Discuss this article

Contribute and read comments about this article: bjgp.org/letters

REFERENCES

  • 1.Legido-Quigley H, Mateos-García JT, Campos VR, et al. The resilience of the Spanish health system against the COVID-19 pandemic. Lancet Public Health. 2020;5(5):e251–e252. doi: 10.1016/S2468-2667(20)30060-8. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 2.de Sutter A, Llor C, Maier M, et al. Family medicine in times of ‘COVID-19’: a generalists’ voice. Eur J Gen Pract. 2020;26(1):58–60. doi: 10.1080/13814788.2020.1757312. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3.Muñoz MA, López-Grau M. Lessons learned from the approach to the COVID-19 pandemic in urban primary health care centres in Barcelona, Spain. Eur J Gen Pract. 2020;26(1):106–107. doi: 10.1080/13814788.2020.1796962. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 4.Fernández-Aguilar C, Casado-Aranda LA, Farrés Fernández M, Minué Lorenzo S. Has COVID-19 changed the workload for primary care physicians? The case of Spain. Fam Pract. 2021;38(6):780–785. doi: 10.1093/fampra/cmab028. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 5.Mortier P, Vilagut G, Ferrer M, et al. Thirty-day suicidal thoughts and behaviors among hospital workers during the first wave of the Spain COVID-19 outbreak. Depress Anxiety. 2021;38(5):528–544. doi: 10.1002/da.23129. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 6.Alonso J, Vilagut G, Mortier P, et al. Mental health impact of the first wave of COVID-19 pandemic on Spanish healthcare workers: a large cross-sectional survey. Rev Psiquiatr Salud Ment (Engl Ed) 2021;14(2):90–105. doi: 10.1016/j.rpsm.2020.12.001. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 7.de Sousa GM, Tavares VDO, de Meiroz Grilo MLP, et al. Mental health in COVID-19 pandemic: a meta-review of prevalence meta-analyses. Front Psychol. 2021;12:703838. doi: 10.3389/fpsyg.2021.703838. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 8.Tawfik DS, Scheid A, Profit J, et al. Evidence relating health care provider burnout and quality of care: a systematic review and meta-analysis. Ann Intern Med. 2019;171(8):555–567. doi: 10.7326/M19-1152. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 9.Harkin D. COVID-19 and medical professionalism in a pandemic. Postgrad Med J. 2021;97(1143):53–54. doi: 10.1136/postgradmedj-2020-138344. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 10.Goddard AF, Patel M. The changing face of medical professionalism and the impact of COVID-19. Lancet. 2021;397(10278):950–952. doi: 10.1016/S0140-6736(21)00436-0. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 11.Zeng X, Peng T, Hao X, et al. Psychological distress reported by primary care physicians in china during the COVID-19 pandemic. Psychosom Med. 2021;83(4):380–386. doi: 10.1097/PSY.0000000000000939. [DOI] [PubMed] [Google Scholar]
  • 12.Lasalvia A, Rigon G, Rugiu C, et al. The psychological impact of COVID-19 among primary care physicians in the province of Verona, Italy: a cross-sectional study during the first pandemic wave. Fam Pract. 2021;39(1):65–73. doi: 10.1093/fampra/cmab106. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 13.Amerio A, Bianchi D, Santi F, et al. Covid-19 pandemic impact on mental health: a web-based cross-sectional survey on a sample of Italian general practitioners. Acta Biomed. 2020;91(2):83–88. doi: 10.23750/abm.v91i2.9619. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 14.Lange M, Joo S, Couette PA, et al. Impact on mental health of the COVID-19 outbreak among general practitioners during the sanitary lockdown period. Ir J Med Sci. 2022;191(1):93–96. doi: 10.1007/s11845-021-02513-6. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 15.Lum A, Goh YL, Wong KS, et al. Impact of COVID-19 on the mental health of Singaporean GPs: a cross-sectional study. BJGP Open. 2021. DOI: . [DOI] [PMC free article] [PubMed]
  • 16.Regenold N, Vindrola-Padros C. Gender matters: a gender analysis of healthcare workers’ experiences during the first COVID-19 pandemic peak in England. Soc Sci. 2021;10(2):43. [Google Scholar]
  • 17.Alonso J, Martin JDDM, Ortí-Lucas RM, et al. MINDCOVID: mental health in a pandemic. https://studies.epidemixs.org/en/proyecto/mindcovid-study-covid-19-mental-health (accessed 31 Mar 2022).
  • 18.Martí T, Peris A, Cerezo J. Country vignette. Spain transforming primary health care during the pandemic: accelerating multidisciplinary teamwork to address emerging primary care needs in three Spanish regions. 2021 https://www.euro.who.int/__data/assets/pdf_file/0016/504331/primary-health-care-Spain-eng.pdf (accessed 18 Mar 2022). [Google Scholar]
  • 19.Wu Y, Levis B, Riehm KE, Saadat N, et al. Equivalency of the diagnostic accuracy of the PHQ-8 and PHQ-9: a systematic review and individual participant data meta-analysis. Psychol Med. 2020;50(8):1368–1380. doi: 10.1017/S0033291719001314. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 20.Díez-Quevedo C, Rangil T, Sánchez-Planell L, et al. Validation and utility of the patient health questionnaire in diagnosing mental disorders in 1003 general hospital Spanish inpatients. Psychosom Med. 2001;63(4):679–686. doi: 10.1097/00006842-200107000-00021. [DOI] [PubMed] [Google Scholar]
  • 21.Newman MG, Zuellig AR, Kachin KE, et al. Preliminary reliability and validity of the generalized anxiety disorder questionnaire-IV: a revised self-report diagnostic measure of generalized anxiety disorder. Behav Ther. 2002;33(2):215–233. [Google Scholar]
  • 22.García-Campayo J, Zamorano E, Ruiz MA, et al. Cultural adaptation into Spanish of the generalized anxiety disorder-7 (GAD-7) scale as a screening tool. Health Qual Life Outcomes. 2010;8:8. doi: 10.1186/1477-7525-8-8. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 23.Kessler RC, Santiago PN, Colpe LJ, et al. Clinical reappraisal of the Composite International Diagnostic Interview Screening Scales (CIDI-SC) in the Army Study to Assess Risk and Resilience in Service members (Army STARRS) Int J Methods Psychiatr Res. 2013;22(4):303–321. doi: 10.1002/mpr.1398. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 24.Blasco MJ, Castellví P, Almenara J, et al. Predictive models for suicidal thoughts and behaviors among Spanish university students: rationale and methods of the UNIVERSAL (university & mental health) project. BMC Psychiatry. 2016;16:122. doi: 10.1186/s12888-016-0820-y. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 25.Zuromski KL, Ustun B, Hwang I, et al. Developing an optimal short-form of the PTSD Checklist for DSM-5 (PCL-5) Depress Anxiety. 2019;36(9):790–800. doi: 10.1002/da.22942. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 26.Mdege ND, Lang J. Screening instruments for detecting illicit drug use/abuse that could be useful in general hospital wards: a systematic review. Addict Behav. 2011;36(12):1111–1119. doi: 10.1016/j.addbeh.2011.07.007. [DOI] [PubMed] [Google Scholar]
  • 27.Díez-Martínez S, Martín-Moros JM, Altisent-Trota R, et al. Brief questionnaires for the early detection of alcoholism in primary health care. Aten Primaria. 1991;8(5):367–370. [PubMed] [Google Scholar]
  • 28.Kessler RC, Ustun TB. The World Mental Health (WMH) survey initiative version of the World Health Organization (WHO) Composite International Diagnostic Interview (CIDI) Int J Methods Psychiatr Res. 2004;13(2):93–121. doi: 10.1002/mpr.168. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 29.Alonso J, Angermeyer MC, Bernert S, et al. Sampling and methods of the European Study of the Epidemiology of Mental Disorders (ESEMeD) project. Acta Psychiatr Scand Suppl. 2004. pp. 8–20. [DOI] [PubMed]
  • 30.Connor KM, Davidson JRT. Development of a new resilience scale: the Connor-Davidson Resilience Scale (CD-RISC) Depress Anxiety. 2003;18(2):76–82. doi: 10.1002/da.10113. [DOI] [PubMed] [Google Scholar]
  • 31.Notario-Pacheco B, Solera-Martínez M, Serrano-Parra MD, et al. Reliability and validity of the Spanish version of the 10-item Connor-Davidson Resilience Scale (10-item CD-RISC) in young adults. Health Qual Life Outcomes. 2011;9:63. doi: 10.1186/1477-7525-9-63. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 32.Sanghera J, Pattani N, Hashmi Y, et al. The impact of SARS-CoV-2 on the mental health of healthcare workers in a hospital setting — a systematic review. J Occup Health. 2020;62(1):e12175. doi: 10.1002/1348-9585.12175. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 33.Vázquez Vega P. [The feminisation of health professionals]. [Article in Spanish] 2010. https://www.fbbva.es/wp-content/uploads/2017/05/dat/DE_2010_feminizacion_profesiones_sanitarias.pdf (accessed 31 Mar 2022).
  • 34.Eurostat Majority of health jobs held by women. 2021. https://ec.europa.eu/eurostat/web/products-eurostat-news/-/edn-20210308-1 (accessed 18 Mar 2022)
  • 35.Lin YH, Chen CY, Wu SI. Efficiency and quality of data collection among public mental health surveys conducted during the COVID-19 pandemic: systematic review. J Med Internet Res. 2021;23(2):e25118. doi: 10.2196/25118. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 36.Cunningham CT, Quan H, Hemmelgarn B, et al. Exploring physician specialist response rates to web-based surveys. BMC Med Res Methodol. 2015;15:32. doi: 10.1186/s12874-015-0016-z. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 37.Kroenke K, Strine TW, Spitzer RL, et al. The PHQ-8 as a measure of current depression in the general population. J Affect Disord. 2009;114(1–3):163–173. doi: 10.1016/j.jad.2008.06.026. [DOI] [PubMed] [Google Scholar]
  • 38.Ruiz MA, Zamorano E, García-Campayo J, et al. Validity of the GAD-7 scale as an outcome measure of disability in patients with generalized anxiety disorders in primary care. J Affect Disord. 2011;128(3):277–286. doi: 10.1016/j.jad.2010.07.010. [DOI] [PubMed] [Google Scholar]
  • 39.Carlos III Health Institute [Covid in Spain. Situation and evolution of the COVID-19 pandemic in Spain. Epidemic curve of the pandemic] 2022. [Article in Spanish]. https://cnecovid.isciii.es/covid19/#ccaa (accessed 31 Mar 2022).
  • 40.Van de Velde S, Boyd A, Villagut G, et al. Gender differences in common mental disorders: a comparison of social risk factors across four European welfare regimes. Eur J Public Health. 2019;29(3):481–487. doi: 10.1093/eurpub/cky240. [DOI] [PubMed] [Google Scholar]
  • 41.Maestre-Miquel C, López-de-Andrés A, Ji Z, et al. Gender differences in the prevalence of mental health, psychological distress and psychotropic medication consumption in Spain: a nationwide population-based study. Int J Environ Res Public Health. 2021;18(12):6350. doi: 10.3390/ijerph18126350. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 42.Liu S, Yang L, Zhang C, et al. Gender differences in mental health problems of healthcare workers during the coronavirus disease 2019 outbreak. J Psychiatr Res. 2021;137:393–400. doi: 10.1016/j.jpsychires.2021.03.014. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 43.Di Tella M, Romeo A, Benfante A, Castelli L. Mental health of healthcare workers during the COVID-19 pandemic in Italy. J Eval Clin Pract. 2020;26(6):1583–1587. doi: 10.1111/jep.13444. [DOI] [PubMed] [Google Scholar]
  • 44.López-Atanes M, Pijoán-Zubizarreta JI, González-Briceño JP, et al. Gender-based analysis of the psychological impact of the COVID-19 pandemic on healthcare workers in Spain. Front Psychiatry. 2021;12:692215. doi: 10.3389/fpsyt.2021.692215. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 45.Klose M, Jacobi F. Can gender differences in the prevalence of mental disorders be explained by sociodemographic factors? Arch Womens Ment Health. 2004;7(2):133–148. doi: 10.1007/s00737-004-0047-7. [DOI] [PubMed] [Google Scholar]
  • 46.Kuehner C. Why is depression more common among women than among men? Lancet Psychiatry. 2017;4(2):146–158. doi: 10.1016/S2215-0366(16)30263-2. [DOI] [PubMed] [Google Scholar]
  • 47.Bracke P, Christiaens W, Wauterickx N. The pivotal role of women in informal care. J Fam Issues. 2008;29(10):1348–1378. [Google Scholar]
  • 48.Xue B, McMunn A. Gender differences in unpaid care work and psychological distress in the UK Covid-19 lockdown. PLoS One. 2021;16(3):e0247959. doi: 10.1371/journal.pone.0247959. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 49.Lai J, Ma S, Wang Y, Cai Z, et al. Factors associated with mental health outcomes among health care workers exposed to coronavirus disease 2019. JAMA Netw Open. 2020;3(3):e203976. doi: 10.1001/jamanetworkopen.2020.3976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 50.Rossi R, Socci V, Pacitti F, et al. Mental health outcomes among frontline and second-line health care workers during the coronavirus disease 2019 (COVID-19) pandemic in Italy. JAMA Netw Open. 2020;3(5):e2010185. doi: 10.1001/jamanetworkopen.2020.10185. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 51.Zhu Z, Xu S, Wang H, Liu Z, et al. COVID-19 in Wuhan: sociodemographic characteristics and hospital support measures associated with the immediate psychological impact on healthcare workers. EClinicalMedicine. 2020;24:100443. doi: 10.1016/j.eclinm.2020.100443. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 52.Hassamal S, Dong F, Hassamal S, et al. The psychological impact of COVID-19 on hospital staff. West J Emerg Med. 2021;22(2):346–352. doi: 10.5811/westjem.2020.11.49015. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 53.Li Z, Ge J, Yang M, Feng J, et al. Vicarious traumatization in the general public, members, and non-members of medical teams aiding in COVID-19 control. Brain Behav Immun. 2020;88:916–919. doi: 10.1016/j.bbi.2020.03.007. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 54.Rostami F, Babaei-Pouya A, Teimori-Boghsani G, et al. Mental workload and job satisfaction in healthcare workers: the moderating role of job control. Front Public Health. 2021;9:683388. doi: 10.3389/fpubh.2021.683388. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 55.Han PKJ, Strout TD, Gutheil C, et al. How physicians manage medical uncertainty: a qualitative study and conceptual taxonomy. Med Decis Making. 2021;41(3):275–291. doi: 10.1177/0272989X21992340. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 56.Solis EC, van Hemert AM, Carlier IVE, et al. The 9-year clinical course of depressive and anxiety disorders: new NESDA findings. J Affect Disord. 2021;295:1269–1279. doi: 10.1016/j.jad.2021.08.108. [DOI] [PubMed] [Google Scholar]
  • 57.Lasalvia A, Bonetto C, Porru S, et al. Psychological impact of COVID-19 pandemic on healthcare workers in a highly burdened area of north-east Italy. Epidemiol Psychiatr Sci. 2020;30:e1. doi: 10.1017/S2045796020001158. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 58.Aburn G, Gott M, Hoare K. What is resilience? An integrative review of the empirical literature. J Adv Nurs. 2016;72(5):980–1000. doi: 10.1111/jan.12888. [DOI] [PubMed] [Google Scholar]
  • 59.Di Trani M, Mariani R, Ferri R, et al. From resilience to burnout in healthcare workers during the COVID-19 emergency: the role of the ability to tolerate uncertainty. Front Psychol. 2021;12:646435. doi: 10.3389/fpsyg.2021.646435. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 60.Riehm KE, Brenneke SG, Adams LB, et al. Association between psychological resilience and changes in mental distress during the COVID-19 pandemic. J Affect Disord. 2021;282:381–385. doi: 10.1016/j.jad.2020.12.071. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 61.Jiménez-Giménez M, Sánchez-Escribano A, Figuero-Oltra MM, et al. Taking care of those who care: attending psychological needs of health workers in a hospital in Madrid (Spain) during the COVID-19 pandemic. Curr Psychiatry Rep. 2021;23(7):44. doi: 10.1007/s11920-021-01253-9. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 62.Joyce S, Shand F, Tighe J, et al. Road to resilience: a systematic review and meta-analysis of resilience training programmes and interventions. BMJ Open. 2018;8(6):e017858. doi: 10.1136/bmjopen-2017-017858. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 63.Albott CS, Wozniak JR, McGlinch BP, et al. Battle buddies: rapid deployment of a psychological resilience intervention for health care workers during the COVID-19 pandemic. Anesth Analg. 2020;131(1):43–54. doi: 10.1213/ANE.0000000000004912. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 64.Martin L, McDoall A. The professional resilience of mid-career GPs in the UK: a qualitative study. Br J Gen Pract. 2021. DOI: . [DOI] [PMC free article] [PubMed]
  • 65.De Simone S, Vargas M, Servillo G. Organizational strategies to reduce physician burnout: a systematic review and meta-analysis. Aging Clin Exp Res. 2021;33(4):883–894. doi: 10.1007/s40520-019-01368-3. [DOI] [PubMed] [Google Scholar]
  • 66.Pollock A, Campbell P, Cheyne J, et al. Interventions to support the resilience and mental health of frontline health and social care professionals during and after a disease outbreak, epidemic or pandemic: a mixed methods systematic review. Cochrane Database Syst Rev. 2020;11(11):CD013779. doi: 10.1002/14651858.CD013779. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from The British Journal of General Practice are provided here courtesy of Royal College of General Practitioners

RESOURCES