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. 2022 Apr 12:ciac288. doi: 10.1093/cid/ciac288

Comparative Effectiveness of mRNA and Inactivated Whole Virus Vaccines against COVID-19 Infection and Severe Disease in Singapore

M Premikha 1,✉, Calvin J Chiew 1, Wycliffe E Wei 1, Yee-Sin Leo 2,3,4,5,6, Benjamin Ong 1,4, David Chien Lye 2,3,4,5, Vernon J Lee 1,6, Kelvin Bryan Tan 1,6
PMCID: PMC9047219  PMID: 35412612

Abstract

Compared to individuals vaccinated with Pfizer-BioNTech/Comirnaty, recipients of Sinovac-CoronaVac and Sinopharm were 2.37 (95% CI 2.29–2.46) and 1.62 (95% CI 1.43–1.85) times more likely to be infected with COVID-19 respectively, while individuals vaccinated with Moderna were 0.42 (95% CI 0.25–0.70) times less likely to develop severe disease.

Keywords: COVID-19, SARS-CoV-2, vaccines, mRNA vaccine, inactivated vaccine

Supplementary Material

ciac288_Supplementary_Data
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Associated Data

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Supplementary Materials

ciac288_Supplementary_Data
Click here for additional data file. (19.4KB, docx)

Articles from Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America are provided here courtesy of Oxford University Press

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