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. 2022 Apr 25;65(11):2335–2337. doi: 10.1007/s11427-022-2112-0

The discovery of type IV interferon system revolutionizes interferon family and opens up a new frontier in jawed vertebrate immune defense

Jianguo Su 1,2,3,
PMCID: PMC9050481  PMID: 35484446

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Compliance and ethics The author(s) declare that they have no conflict of interest.

References

  1. Chen, S.N., Gan, Z., Hou, J., Yang, Y.C., Huang, L., Huang, B., Wang, S., and Nie, P. (2022). Identification and establishment of type IV interferon and the characterization of interferon-υ including its class II cytokine receptors IFN-υR1 and IL-10R2. Nat Commun 13, 999. [DOI] [PMC free article] [PubMed]
  2. Gan Z, Chen SN, Huang B, Zou J, Nie P. Fish type I and type II interferons: composition, receptor usage, production and function. Rev Aquacult. 2020;12:773–804. doi: 10.1111/raq.12349. [DOI] [Google Scholar]
  3. Gui JF, Zhou L, Li XY. Rethinking fish biology and biotechnologies in the challenge era for burgeoning genome resources and strengthening food security. Water Biol Security. 2022;1:100002. doi: 10.1016/j.watbs.2021.11.001. [DOI] [Google Scholar]
  4. Li Y, Xiao T, Zou J. Fish TNF and TNF receptors. Sci China Life Sci. 2021;64:196–220. doi: 10.1007/s11427-020-1712-4. [DOI] [PubMed] [Google Scholar]
  5. Secombes CJ, Zou J. Evolution of interferons and interferon receptors. Front Immunol. 2017;8:209. doi: 10.3389/fimmu.2017.00209. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Xiao X, Zhu W, Zhang Y, Liao Z, Wu C, Yang C, Zhang Y, Xiao S, Su J. Broad-spectrum robust direct bactericidal activity of fish IFNφ1 reveals an antimicrobial peptide-like function for type I IFNs in vertebrates. J Immunol. 2021;206:1337–1347. doi: 10.4049/jimmunol.2000680. [DOI] [PubMed] [Google Scholar]

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