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. 2022 May 2;41(8):727. doi: 10.1016/j.repc.2021.08.009

Myocarditis and COVID-19 mRNA vaccination

Miocardite e vacina mRNA anti-Covid 19

Rujittika Mungmunpuntipantip a, Viroj Wiwanitkit b,
PMCID: PMC9057931  PMID: 35530373

To the Editor:

We would like to comment on “Acute myocarditis after SARS-CoV-2 vaccination in a 24-year-old man” by Cimaglia et al.1 They reported an interesting case and concluded that “myocarditis may also occur after administering the vaccine against SARS-CoV-2.” Regarding pathomechanisms, Cimaglia et al. discussed the role of autoimmunity.1 If there is an immunopathological process, an abnormal immunoglobulin profile should be demonstrated. An abnormal immune response might be a cause but there are also other possible causes, one of which is the induction of hyperviscosity by vaccination.2 A relationship between hyperviscosity and acute myocarditis has been confirmed3 and hyperviscosity induced by vaccination might also be a cause of myocarditis.4

Conflicts of interest

The authors have no conflicts of interest to declare.

References

  • 1.Cimaglia P., Tolomeo P., Rapezzi C. Acute myocarditis after SARS-CoV-2 vaccination in a 24-year-old man. Rev Port Cardiol. 2021 doi: 10.1016/j.repc.2021.07.005. S0870-2551(21)00324-3. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 2.Joob B., Wiwanitkit V. Expected viscosity after COVID-19 vaccination, hyperviscosity and previous COVID-19. Clin Appl Thromb Hemost. 2021;27 doi: 10.1177/10760296211020833. 10760296211020833. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3.Sanchez-Petitto G., Hardy N., Burke A., et al. Eosinophilic myocarditis in a patient with multiple myeloma. Clin Lymphoma Myeloma Leuk. 2020;20:e392–e394. doi: 10.1016/j.clml.2020.03.015. [DOI] [PubMed] [Google Scholar]
  • 4.Sookaromdee P., Wiwanitkit V. Acute myocardial injury following COVID-19 vaccination. J Prim Care Community Health. 2021;12 doi: 10.1177/21501327211039986. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Revista Portuguesa De Cardiologia are provided here courtesy of Elsevier

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