To the Editor:
We would like to comment on “Acute myocarditis after SARS-CoV-2 vaccination in a 24-year-old man” by Cimaglia et al.1 They reported an interesting case and concluded that “myocarditis may also occur after administering the vaccine against SARS-CoV-2.” Regarding pathomechanisms, Cimaglia et al. discussed the role of autoimmunity.1 If there is an immunopathological process, an abnormal immunoglobulin profile should be demonstrated. An abnormal immune response might be a cause but there are also other possible causes, one of which is the induction of hyperviscosity by vaccination.2 A relationship between hyperviscosity and acute myocarditis has been confirmed3 and hyperviscosity induced by vaccination might also be a cause of myocarditis.4
Conflicts of interest
The authors have no conflicts of interest to declare.
References
- 1.Cimaglia P., Tolomeo P., Rapezzi C. Acute myocarditis after SARS-CoV-2 vaccination in a 24-year-old man. Rev Port Cardiol. 2021 doi: 10.1016/j.repc.2021.07.005. S0870-2551(21)00324-3. [DOI] [PMC free article] [PubMed] [Google Scholar]
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