Abstract
(Appeared originally in Brain Stimulation 2018; 11:492–500)
Reprinted with permission from Elsevier
. 2022 Jan 25;20(1):80–89. doi: 10.1176/appi.focus.20110
Neurophysiologic Effects of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) via Electrical Stimulation of the Tragus: A Concurrent taVNS/fMRI Study and Review
Bashar W Badran
1,✉, Logan T Dowdle
1, Oliver J Mithoefer
1, Nicholas T LaBate
1, James Coatsworth
1, Joshua C Brown
1, William H DeVries
1, Christopher W Austelle
1, Lisa M McTeague
1, Mark S George
1
Bashar W Badran
1Department of Neuroscience, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Psychiatry, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Psychology, University of New Mexico, Albuquerque, NM, 87131, United States; US Army Research Lab, Aberdeen Proving Ground, MD, 21005, United States; College of Charleston, Charleston, SC, 29403, United States; Center for Biomedical Imaging, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Neurology, Medical University of South Carolina, Charleston, SC, 29425, United States; Ralph H. Johnson VA Medical Center, Charleston, SC, 29401, United States.
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Logan T Dowdle
1Department of Neuroscience, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Psychiatry, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Psychology, University of New Mexico, Albuquerque, NM, 87131, United States; US Army Research Lab, Aberdeen Proving Ground, MD, 21005, United States; College of Charleston, Charleston, SC, 29403, United States; Center for Biomedical Imaging, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Neurology, Medical University of South Carolina, Charleston, SC, 29425, United States; Ralph H. Johnson VA Medical Center, Charleston, SC, 29401, United States.
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Oliver J Mithoefer
1Department of Neuroscience, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Psychiatry, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Psychology, University of New Mexico, Albuquerque, NM, 87131, United States; US Army Research Lab, Aberdeen Proving Ground, MD, 21005, United States; College of Charleston, Charleston, SC, 29403, United States; Center for Biomedical Imaging, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Neurology, Medical University of South Carolina, Charleston, SC, 29425, United States; Ralph H. Johnson VA Medical Center, Charleston, SC, 29401, United States.
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Nicholas T LaBate
1Department of Neuroscience, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Psychiatry, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Psychology, University of New Mexico, Albuquerque, NM, 87131, United States; US Army Research Lab, Aberdeen Proving Ground, MD, 21005, United States; College of Charleston, Charleston, SC, 29403, United States; Center for Biomedical Imaging, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Neurology, Medical University of South Carolina, Charleston, SC, 29425, United States; Ralph H. Johnson VA Medical Center, Charleston, SC, 29401, United States.
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James Coatsworth
1Department of Neuroscience, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Psychiatry, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Psychology, University of New Mexico, Albuquerque, NM, 87131, United States; US Army Research Lab, Aberdeen Proving Ground, MD, 21005, United States; College of Charleston, Charleston, SC, 29403, United States; Center for Biomedical Imaging, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Neurology, Medical University of South Carolina, Charleston, SC, 29425, United States; Ralph H. Johnson VA Medical Center, Charleston, SC, 29401, United States.
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Joshua C Brown
1Department of Neuroscience, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Psychiatry, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Psychology, University of New Mexico, Albuquerque, NM, 87131, United States; US Army Research Lab, Aberdeen Proving Ground, MD, 21005, United States; College of Charleston, Charleston, SC, 29403, United States; Center for Biomedical Imaging, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Neurology, Medical University of South Carolina, Charleston, SC, 29425, United States; Ralph H. Johnson VA Medical Center, Charleston, SC, 29401, United States.
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William H DeVries
1Department of Neuroscience, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Psychiatry, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Psychology, University of New Mexico, Albuquerque, NM, 87131, United States; US Army Research Lab, Aberdeen Proving Ground, MD, 21005, United States; College of Charleston, Charleston, SC, 29403, United States; Center for Biomedical Imaging, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Neurology, Medical University of South Carolina, Charleston, SC, 29425, United States; Ralph H. Johnson VA Medical Center, Charleston, SC, 29401, United States.
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Christopher W Austelle
1Department of Neuroscience, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Psychiatry, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Psychology, University of New Mexico, Albuquerque, NM, 87131, United States; US Army Research Lab, Aberdeen Proving Ground, MD, 21005, United States; College of Charleston, Charleston, SC, 29403, United States; Center for Biomedical Imaging, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Neurology, Medical University of South Carolina, Charleston, SC, 29425, United States; Ralph H. Johnson VA Medical Center, Charleston, SC, 29401, United States.
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Lisa M McTeague
1Department of Neuroscience, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Psychiatry, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Psychology, University of New Mexico, Albuquerque, NM, 87131, United States; US Army Research Lab, Aberdeen Proving Ground, MD, 21005, United States; College of Charleston, Charleston, SC, 29403, United States; Center for Biomedical Imaging, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Neurology, Medical University of South Carolina, Charleston, SC, 29425, United States; Ralph H. Johnson VA Medical Center, Charleston, SC, 29401, United States.
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Mark S George
1Department of Neuroscience, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Psychiatry, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Psychology, University of New Mexico, Albuquerque, NM, 87131, United States; US Army Research Lab, Aberdeen Proving Ground, MD, 21005, United States; College of Charleston, Charleston, SC, 29403, United States; Center for Biomedical Imaging, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Neurology, Medical University of South Carolina, Charleston, SC, 29425, United States; Ralph H. Johnson VA Medical Center, Charleston, SC, 29401, United States.
Find articles by Mark S George
1Department of Neuroscience, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Psychiatry, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Psychology, University of New Mexico, Albuquerque, NM, 87131, United States; US Army Research Lab, Aberdeen Proving Ground, MD, 21005, United States; College of Charleston, Charleston, SC, 29403, United States; Center for Biomedical Imaging, Medical University of South Carolina, Charleston, SC, 29425, United States; Department of Neurology, Medical University of South Carolina, Charleston, SC, 29425, United States; Ralph H. Johnson VA Medical Center, Charleston, SC, 29401, United States.
✉
Corresponding author. MUSC Institute of Psychiatry, 67 President St., 504N, Charleston, SC, 29425, United States. E-mail address: badran@musc.edu (B.W. Badran).
✉
Corresponding author.
Received 2017 Jul 23; Revised 2017 Nov 11; Accepted 2017 Dec 22; Issue date 2022 Jan.
Copyright © 2022 by the American Psychiatric Association
PMCID: PMC9063605 PMID: 35746927