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. 2022 May 8;38(3):449–459. doi: 10.1016/j.cger.2022.05.002

Lifestyle Changes and Psychological Well-Being in Older Adults During COVID-19 Pandemic

Matteo Tosato a,, Francesca Ciciarello a, Maria Beatrice Zazzara a, Delfina Janiri a, Cristina Pais a, Stefano Cacciatore a, Rossella Montenero a, Maria Sandrina Leone a, Enea Chisci a, Anna Picca a, Vincenzo Galluzzo a, Hélio José Coelho-Junior b, Riccardo Calvani a, Emanuele Marzetti a,b, Francesco Landi a,b; , on behalf of Gemelli Against COVID-19 Post-Acute Care Team
PMCID: PMC9080082  PMID: 35868665

Abstract

COVID-19 pandemic forced countries to adopt strategies aimed at responding to the health emergency by containing contagion. Lockdowns have ensured the achievement of this goal but imposed substantial restrictions to the freedom of movement and resulted in social isolation for a large share of vulnerable people. The aim of the present study was to evaluate the impact of COVID-19 pandemic and associated emergency restriction measures on the quality of life, lifestyle habits, and psychosocial status in older adults.

Keywords: Older adults, COVID-19, Frailty, Quality of life, Mobility disorders

Key points

  • Emergency restrictions aimed at reducing contagion elicited lifestyle modification.

  • The impact of nonpharmacologic interventions against COVID-19 pandemic was particularly significant in older adults.

  • Main consequences of restrictions in older persons were lifestyle modifications, reduced quality of life, and overall well-being, worsening in mobility and depression.

Introduction

The advent of the COVID-19 pandemic disrupted our habits and lives. The updated numbers of infections and deaths in the world's population are staggering. To date, pandemic figures reached more than 500 million cases and more than 6,000,000 deaths.1 The risk factors for developing more severe forms of the disease are advanced age, obesity, multimorbidity, immunodeficiency, and preexisting disorders affecting lung, heart, liver, and the kidneys.2 In particular, advanced age (85+ years) is the most significant independent risk factor associated with intensive care unit admission and in-hospital mortality.3

National health systems, even those of the most developed countries, were severely challenged by COVID-19 pandemic and urged emergency political decisions aimed at containing contagion and its burdensome consequences. Large-scale nonpharmaceutical interventions were put in place, including social distancing, school closures, isolation of symptomatic people and their contacts, and generalized lockdowns.4 Restrictive measures had a large effect in reducing SARS-CoV-2 transmission but, at the same time, heavily affected the daily life of a large share of people, including more vulnerable people.5 Older adults, especially when multimorbid and frail, were asked to comply even more strictly with those restrictions. Despite the fact that public health measures protected thousands of older adults from the negative COVID-19 health outcomes, unintended detrimental consequences were experienced by the older age classes.6 Notably, social isolation and reduced physical activity are well-acknowledged risk factors for negative health outcomes in the elderly population. Specifically, social isolation is associated with reduced quality of life, reduced muscle mass, cognitive function, multimorbidity, and disability.7, 8, 9 Physical inactivity has a significant impact on health, quality of life, cognitive impairment, falls, depression, disability, hospitalization, and mortality.10

Moreover, study coming from previous coronavirus pandemics demonstrated impaired quality of life, depression, and psychological discomfort.11

In light of this evidence, several concerns exist regarding the long-term outcomes of restrictions placed on the elderly population. The aim of this study was to evaluate the impact of public health measures to mitigate COVID-19 pandemic on subjects older than 80 years, who have not suffered COVID-19, in terms of quality of life, changes in their daily habits, and psychological discomfort.

Evaluation

We conducted an observational study in community dwellers aged 80+ years consecutively referring to the vaccination center against Sars-CoV-2 at Fondazione Policlinico Universitario Agostino Gemelli IRCCS of Rome, Italy. Participants were asked to complete a dedicated questionnaire. The questionnaire was composed of 4 sections. In the first section, demographic, anthropometric, and clinical information were collected, including age, gender, education, body height and weight, diseases, and drug therapy, together with data regarding changes in individual daily habits (such as perturbations of previous usual activities, attendance to places of worship or senior centers, physical activity routines, access to health care services). The second section evaluated the quality of life at the time of the assessment compared with the prepandemic time using a visual analogue scale (0–100). Mobility difficulty and depression status were also compared across the same timeframe. The third section assessed subjective psychological well-being using the 5-item World Health Organization Well-Being Index (WHO-5).12 , 13 WHO-5 consists of 5 questions assessing the subjective well-being of the participants. The items are on a 5-point Likert scale ranging from 0 “at no time” to 5 “all of the time.” The final score is calculated by summing the single items and ranges from 0 to 25, with 0 representing the worst imaginable well-being and 25 representing the best imaginable well-being. The WHO-5 is among the most widely used questionnaires assessing subjective psychological well-being, and it has showed a good internal and external validity in elderly population. A significant worsening in the quality of life was defined as a loss of at least 5 points in the visual analogue scale and/or a WHO score less than or equal to 15.

Finally, the last section assessed psychological distress related to the restrictions put in place to counteract the Sars CoV2 pandemic, through Kessler 10 Psychological Distress Scale (K10).14 K10 is a 10-item questionnaire providing a global measure of distress based on questions about anxiety and depressive symptoms experienced in the last 4 week. Items are rated using a 5-point Likert scale ranging from 1 (never) to 5 (always). Score may range from 10 to 50. Low scores indicate low levels of psychological distress, whereas high scores indicate high levels of psychological distress. Consistently with previous validation studies15 , 16 we adopted the cut-off score of greater than 19 to detect the likelihood of presence of psychological distress. The K-10 can be used with confidence in general-purpose health surveys and when assessing psychological distress in old-age communities.

At the end of the questionnaire, the study personnel assessed the frailty status of the study participants using the Clinical Frailty Status.17

The only exclusion criterion was the unwillingness to participate.

Statistical Analyses

Study participants were categorized into 2 groups: individuals who had changed lifestyle during the COVID-19 pandemic and individuals who reported no change. The 2 groups were compared on demographic and key clinical characteristics, quality of life, and psychological distress. Continuous variables were expressed as mean, and categorical variables were expressed as frequencies by absolute value and percentage of the total. Differences in proportions and means between the 2 groups were assessed using Fisher exact test and t-test statistics, respectively. The level of statistical significance was set at P>.05. Factors significantly associated with lifestyle change in bivariate analyses, together with age and sex, subsequently underwent a multivariate logistic regression to generate odds atios (ORs) and their 95% confidence intervals, with lifestyle change as dependent outcome measure. We examined possible multicollinearity between variables of interest by ensuring that the variance inflation factor indicator obtained from linear regression analysis was less than 4. We used the statistical routines of SPSS Statistics 24.0 for Windows (IBM Co., Armonk, New York, USA).

Discussion

We collected data from 504 participants; main characteristics are summarized in Table 1 . Briefly, mean age of our population was 83.2 years, and 56% were women. More common diseases were hypertension (55%), arrhythmia (16%), diabetes (15%), ischemic heart disease (11%), any cancer (10%), and osteoarthritis (10%). Mean number of diseases was 2.1 and mean number of drugs 3.6. Most of the participants had taken flu vaccination (85%), whereas only 36% had taken pneumococcal vaccination. Around 78% of participants performed routine blood check in the previous year, and 64% were visited by general practitioners. The mean score of clinical frailty scale was 3.5 ± 1.3.

Table 1.

General and clinical characteristics of study population according to lifestyle change during COVID-19 pandemic era

Characteristics Total Sample (n = 504) Lifestyle Change
p
NO (n = 220) YES (n = 284)
Age (y) 83.2 ± 5.1 83.8 ± 4.5 82.8 ± 5.5 0.02
Gender
 Male 221 (44) 104 (47) 117 (41) 0.10
 Female 283 (56) 116 (53) 167 (59)
Education (y) 11.4 ± 5.3 10.7 ± 6.0 11.8 ± 4.7 0.01
Hypertension 276 (55) 117 (53) 159 (56) 0.28
Ischemic heart disease 55 (11) 26 (12) 29 (10) 0.34
Arrhythmia 80 (16) 32 (15) 48 (17) 0.27
Diabetes 75 (15) 36 (16) 39 (14) 0.24
Renal failure 14 (3) 6 (3) 8 (3) 0.58
COPD 33 (7) 18 (8) 15 (5) 0.13
Cancer 49 (10) 17 (8) 32 (11) 0.11
Osteoarthritis 41 (8) 18 (8) 23 (8) 0.55
Number of diseases 2.1 ± 1.4 2.3 ± 1.5 2.1 ± 1.2 0.12
Number of drugs 3.6 ± 2.8 3.8 ± 2.9 3.5 ± 2.6 0.20
Flu vaccination 427 (85) 189 (86) 238 (84) 0.30
Pneumococcal vaccination 183 (36) 78 (36) 105 (37) 0.39
Routine blood check 397 (78) 166 (76) 231 (81) 0.07
General practitioner visit 321 (64) 131 (60) 190 (67) 0.05
Clinical frailty scale 3.5 ± 1.3 3.7 ± 1.3 3.3 ± 1.3 <0.01

Data are given as number (percent) for gender, diseases, flu and pneumococcal vaccination, blood check, and general practitioner visit; for all the other variables, means ± SD are reported.

We stratified our study sample into 2 groups, based on their self-reported change in daily routines. In the whole study sample, 284 older adults (56.3%) reported substantial lifestyle changes following COVID-19 pandemic and 220 individuals (43, 7%) preserved their prepandemic habitual activities. The 2 groups differed by age (P = .02), education (P = .01), and clinical frailty scale (P<.01). Specifically, study participants reporting lifestyle changes were younger, with higher level of education and a lower score at the clinical frailty scale. Furthermore, in the same group, a higher percentage of individuals reported a worsening in the quality of life compared with prepandemic time (Table 2 ). Multivariate logistic regression identified the worsening at the visual analogue scale as a specific risk factor for lifestyle change (OR = 2.03; P<.001), whereas clinical frailty score was associated with the preservation of prepandemic activities (OR = 0.78; P = .001) (Table 3 ).

Table 2.

Quality of life and psychological well-being of study population according to lifestyle change during COVID-19 pandemic era∗

Characteristics Total Sample (n = 504) Lifestyle Change
p
NO (n = 220) YES (n = 284)
Self-rated health (visual analogue scale)
 VAS pre-COVID-19 76.5 ± 16.9 75.8 ± 18.3 77.0 ± 15.8 0.42
 VAS COVID-19 era 69.6 ± 19.2 70.7 ± 19.8 68.7 ± 18.8 0.25
 Worsened EQ-VAS 217 (43) 75 (35) 142 (65) <0.001
WHO-5: The 5-item World Health Organization Well-Being Index
 WHO-5 15.8 ± 5.2 16.3 ± 5.4 15.4 ± 5.0 0.07
 WHO-5 ≤15 229 (45) 87 (39) 142 (50) 0.01
K10 test—Kessler Psychological Distress Scale
 K10 test 16.0 ± 4.8 15.7 ± 4.9 16.2 ± 4.8 0.23
 K10 test more than 19 116 (23) 46 (21) 70 (25) 0.19

Worsened quality of life: greater than 5 points lost at VAS.

WHO-5: The World Health Organisation—Five Well-Being Index (ranging from 0 to 25, with 0 representing the worst imaginable well-being and 25 representing the best imaginable well-being).

K10 test: Kessler Psychological Distress Scale (ranging from 0 to 50, with 0 representing the better result and 50 representing the worsen result).

Table 3.

Multivariate logistic regression (NO lifestyle change vs YES lifestyle change)

OR [95% CI] Wald p
Gender 1.27 [0.87–1.86] 1.59 0.20
Age 0.98 [0.94–1.02] 0.90 0.34
Education 1.03 [0.99–1.06] 3.14 0.07
Heart failure 0.45 [0.20–1.05] 3.35 0.06
Clinical frailty scale 0.78 [0.67–0.91] 10.15 0.001
Worsened EQ-VAS 2.03 [1.38–3.00] 12.89 <0.001
WHO-5 ≤15 1.46 [0.98–2.16] 3.56 0.06

Significant results in bold.

Abbreviations: CI, confidence interval; OR, odds ratio; p, statistical significance.

In Fig. 1 we reported the usual activities interrupted because of the pandemic. The most affected habitual routine was the visit to relatives and friends (reported by 46.5% of study participants), followed by physical activity (45.8%), participation to religious services (19.7%), cinema and theater show attendance (18.1%), shopping (12.7%), travel (7.7%), and work activities (6.1%).

Fig. 1.

Fig. 1

Usual activities interrupted during pandemic.

As for the mobility status, the percentage of the study participants reporting no difficulty in mobility reduced from 57.4% in the prepandemic phase to 43.2%. People reporting moderate difficulty increased from 37% to 44.7%, whereas older adults reporting severe difficulty increased from 5.6% to 12.1% (Fig. 2 ).

Fig. 2.

Fig. 2

Self-report difficulty in mobility before and during COVID-19 pandemic.

A similar trend was observed for the depression status. Indeed, at the time of evaluation only 43.9% reported no depression compared with 76.3% in the prepandemic time, 50.3% reported moderate depression (vs 22% pre-COVID-19 time), and 5.8% reported severe depression (vs 1.7%) (Fig. 3 ).

Fig. 3.

Fig. 3

Self-report depression status before and during COVID-19 pandemic.

Older adults, in particular the multimorbid and frail older population, were the most heavily affected population segment in terms of negative health outcomes and mortality during COVID-19 pandemic.18 The latest Italian report estimated that around 85% of deaths occurred in people aged 70 years or older.19 However, people in the oldest age groups were also the most affected by the emergency restrictive measures put in place to contain contagion due to their intrinsic vulnerability.20 Indeed, social distancing, loneliness, and difficulty in accessing care caused by the anti-COVID-19 public health measures may have further increased the risk for several negative outcomes, including reduction of quality of life, cognitive impairment, falls, depression, disability.21

Studies on the topic showed conflicting results. A study conducted in individuals aged 50+ years from Italy, Spain, and France reported that about 50% of participants felt sad or depressed more often than usual during the lockdown.22 Similarly, in Australian older adults receiving home- and community-based services, quality of life significantly worsened during the pandemic compared with the previous year.23 In community-dwelling older adults from United States, a higher rate of depression and loneliness was reported following the onset of the pandemic.24 In middle-aged and older adults from the Canadian Longitudinal Study on Aging the odds of depressive symptoms doubled during the pandemic compared with the prepandemic period.25

However, an online survey involving 825 US adults aged 60 years and older revealed that confinement/restrictions, although listed among the most stressful events of the pandemic, were not associated with negative indicators of psychological well-being.26 Moreover, a longitudinal study conducted in Sweden concluded that COVID-19 had only minimal effects on well-being in older adults.27 Notably, in the early pandemic phase, many Swedish older adults rated their well-being as high as or even higher than previous years. Data collected from more than 36,000 English adults of the UCL COVID-19 Social Study showed that anxiety and depressive symptoms increased during the early stages of lockdown, but with a fast improvement within a few weeks.28

Finally, in 720 people from the Fifth National Survey on Quality of Life in Older Adults in Chile, Herrera and colleagues found no changes in self-rated health in older adults during the pandemic, although some health indicators, including depression and anxiety, worsened.29

Collectively, those findings highlighted a huge heterogeneity of responses to pandemic public health measures in older adults and suggested that many older individuals may have substantial adaptive capacity and resilience.

Our results showed a significant impact of restrictive measures in community-dwelling older adults aged older than 80 years who have not contracted SARS-CoV-2 infection. Specifically, of the 504 subjects interviewed, 284 (56%) reported substantial lifestyle modifications. The main activities interrupted were visits to relatives (46%), physical activity (45.8%), attending religious services (19.7%), and cinema/theater (18.1%). Notably, although 57.4% of participants reported having no difficulty in terms of mobility before the pandemic, this percentage dropped alarmingly to 43.2%. The same pattern was observed in those who had moderate difficulty (that increased from 37% to 44.7%) and those who had severe difficulty (from 5.6% to 12.1%) increased. Mobility is critical for living independently. Older adults who lose their mobility have poorer quality of life and higher risk of several medium- to long-term negative outcomes including falls, cognitive impairment, disability, disease, hospitalization, and death.30, 31, 32

In this context, the increase in mobility difficulty reported by our participants is quite concerning for the overall impact this may have from both health and socioeconomic perspectives. Not surprisingly, we also found a similar trend in depression figures, with the percentage of study participants reporting no depressive symptoms that dropped from 76.3% in the pre-COVID era to 43.9%. A concomitant increase was found for moderate and severe depression.

In addition, our data showed that people who most likely made lifestyle changes were younger, with higher education status and better Clinical Frailty Scale scores. As expected, the reduction in quality of life, as well as the reduced psychosocial well-being, was more evident in subjects who modified their lifestyles.

Summary

Restrictive measures aimed at containing COVID-19 pandemic had a significant impact on lifestyle habits, quality of life, psychosocial well-being, and mobility in individuals older than 80 years who have not contracted SARS-CoV-2 infection. A comprehensive multidimensional assessment should be routinely implemented to determine and manage the potential negative consequences of public health measures on overall health status and quality of life of older adults.

Clinics care points

  • Restrictive measures to contain COVID-19 pandemic caused substantial lifestyle modifications, reduced quality of life and psychosocial well-being, and increased mobility deficits in older adults.

  • People who most likely made lifestyle changes were younger, with higher education status and better Clinical Frailty Scale scores.

  • The reduction in quality of life and psychosocial well-being was more evident in subjects who modified their lifestyles.

  • Approaches based on multidimensional assessments should be implemented to minimize the negative health outcomes in this vulnerable population segment.

Acknowledgments

The author is grateful to thank "The Gemelli Against COVID-19 Post-Acute Care Study Group".

The Gemelli Against COVID-19 Post-Acute Care Study Group is composed as follows:

Steering committee: Landi Francesco, Gremese Elisa. Coordination: Bernabei Roberto, Fantoni Massimo, Antonio Gasbarrini. Field investigators: • Gastroenterology team: Settanni Carlo Romano, Porcari Serena. • Geriatric team: Benvenuto Francesca, Bramato Giulia, Brandi Vincenzo, Carfì Angelo, Ciciarello Francesca, Lo Monaco Maria Rita, Martone Anna Maria, Marzetti Emanuele, Napolitano Carmen, Galluzzo Vincenzo, Pagano Francesco, Pais Cristina, Rocchi Sara, Rota Elisabetta, Salerno Andrea, Tosato Matteo, Tritto Marcello, Calvani Riccardo, Zazzara Maria Beatrice, Catalano Lucio, Picca Anna, Savera Giulia. • Infectious disease team: Cauda Roberto, Murri Rita, Cingolani Antonella, Ventura Giulio, Taddei Eleonora, Moschese Davide, Ciccullo Arturo, Fantoni Massimo. • Internal Medicine team: Stella Leonardo, Addolorato Giovanni, Franceschi Francesco, Mingrone Gertrude, Zocco Maria Assunta. • Microbiology team: Sanguinetti Maurizio, Cattani Paola, Marchetti Simona, Posteraro Brunella, Sali Michela. • Neurology team: Bizzarro Alessandra, Alessandra Lauria. • Ophthalmology team: Rizzo Stanislao, Savastano Maria Cristina, Gambini Gloria, Cozzupoli Grazia Maria, Culiersi Carola.Otolaryngology team: Passali Giulio Cesare, Paludetti Gaetano, Galli Jacopo, Crudo Fabrizio, Di Cintio Giovanni, Longobardi Ylenia, Tricarico Laura, Santantonio Mariaconsiglia, Di Cesare Tiziana, Guarino Mariateresa, Corbò Marco, Settimi Stefano, Mele Dario, Brigato Francesca. • Pediatric team: Buonsenso Danilo, Valentini Piero, Sinatti Dario, De Rose Gabriella. • Pneumology team: Richeldi Luca, Lombardi Francesco, Calabrese Angelo, Varone Francesco, Leone Paolo Maria, Siciliano Matteo, Corbo Giuseppe Maria, Montemurro Giuliano, Calvello Mariarosaria, Intini Enrica, Simonetti Jacopo, Pasciuto Giuliana, Adiletta Veronica, Sofia Carmelo, Licata Maria Angela. • Psychiatric team: Sani Gabriele, Delfina Janiri, Simonetti Alessio, Modica Marco, Montanari Silvia, Catinari Antonello, Terenzi Beatrice. • Radiology team: Natale Luigi, Larici Anna Rita, Marano Riccardo, Pirronti Tommaso, Infante Amato. • Rheumatology team: Paglionico Annamaria, Petricca Luca, Tolusso Barbara, Alivernini Stefano, Di Mario Clara. • Vascular team: Santoliquido Angelo, Santoro Luca, Nesci Antonio, Di Giorgio Angela, D’Alessandro Alessia.

Disclosure

No conflict of interest to disclosure.

Footnotes

This study was supported by Ministero della Salute - Ricerca Corrente 2022.

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