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. 2022 Apr 8;14(4):e23959. doi: 10.7759/cureus.23959

Figure 1. Network of direct and indirect pathways of basal ganglia involved in motor activity and psychotic symptoms; stimulation and increased activity of excessive D2 receptors in the associative striatum causing schizophrenia.

Figure 1

Original image created by the authors.

D1 - dopamine D1 receptor in the excitatory pathway; D2 - dopamine D2 receptor in the inhibitory pathway; SNc - substantia nigra pars compact; GPe - globus pallidus externus; GPi - globus pallidus internus; STN - subthalamic nucleus