FIGURE 1.

Zinc role in the interaction with the gut microbiota: Zinc variable concentration (namely, affected by several factors) is able to affect GM composition balance leading to “dysbiosis” “or maintaining” “eubiosis.” This interaction is reciprocal. Other factors play a role in maintaining this balance (e.g., diet, use of pre‐, pro‐, postbiotics, and antibiotics). GM dysbiosis is associated with several pathophysiologic manifestations. GM eubiosis is essential to human health (e.g., maintaining immune system surveillance and tolerance function, regulating metabolism, inflammation, cell proliferation)