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. 2022 May 5;14(9):1938. doi: 10.3390/nu14091938

Table 2.

Total number of comparisons identified, and numbers identified by zinc vs. no zinc comparisons available in all identified studies by age group and outcome 1.

Ages 2 Serum or Plasma Copper Serum Ceruloplasmin ESOD Serum Ferritin Hemoglobin Serum Transferrin Receptor Lipids Dose Ranges of Studies by Age 3 (mg)
0–5 months 1 0 0 2 1 0 1 4–5
6–12 months 11 0 1 20 25 6 1 2.3–10
1–3 years 3 1 2 11 18 2 0 0.9–20
4–6 years 5 0 0 5 9 0 1 1.2–21.4
7+ years 3 4 3 1 3 0 1 2.8–17.1
Total 23 5 6 39 56 8 4 0.9–21.4

Original to this manuscript: 1 Sorting is subjective, using the mean initial age and the time period in which most of the intervention took place (for example, if the mean initial age was 4 months and the study lasted 6 months, the study was counted in the 6–12-month age range); 44 total studies provided these 141 comparisons (Tables S1–S7). 2 Age ranges are similar to those used to develop RI and UL recommendations (Table 1). 3 Daily supplemental doses of zinc provided in the studies in this review, by mean initial age (Tables S1–S7).