Abbreviations: AF, atrial fibrillation; ASCEND, A Study of Cardiovascular Events in Diabetes; DHA, docosahexaenoic acid; HR, hazard ratio; GISSI-HF, Gruppo Italiano per lo Studio della Sopravvi- venza nell’Insufficienza Cardiaca; OMEMI, Omega-3 fatty acids in Elderly with Myocardial Infarction; REDUCE-IT, Reduction of Cardiovascular Events with Icosapent Ethyl-Intervention Trial; RP, The Risk and Prevention Study; STRENGTH, Long-Term Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh Cardiovascular Risk PatienTs With Hypertriglyceridemia; VITAL, The Vitamin D and Omega-3 Trial.