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. 2022 Apr 12;26(5):1049. doi: 10.1111/1744-9987.13849

Acute kidney injury, mortality, and COVID‐19: Correspondence

Rujittika Mungmunpuntipantip 1,, Viroj Wiwanitkit 2
PMCID: PMC9111285  PMID: 35385204

Dear Editor,

We would like to share ideas on the publication “The incidence of acute kidney injury (AKI) and its association with mortality in patients diagnosed with COVID‐19 followed‐up in intensive care uni. 1 ” Bayrakci et al. noted that “AKI is frequently seen during the course of COVID‐19 and is associated with high mortality. Identifying AKI‐related risk factors appears essential in the management of COVID‐1. 1 ” We agree that AKI is a possible clinical problem in coronavirus disease‐2019 (COVID‐19). Background medical problems might be a risk for developing AKI and the finding in the present study also support this fact. In an early report from Asia during the early emerging COVID‐19, the AKI is rare. 2 Whether the observed incidence in the present study by Bayrakci et al. reflects a possible high background incidence of silent kidney problem is a question. Regarding the mechanism that causes AKI in COVID‐19, it is still unclear. Abnormal immunopathology and immune complex formation might be a possible mechanism. 3 Additionally, a change in blood viscosity in COVID‐19 might also aggravate AKI. 4

CONFLICT OF INTEREST

None.

REFERENCES

  • 1. Bayrakci N, Özkan G, Şakaci M, Sedef S, Erdem İ, Tuna N, Mutlu LC, Yildirim İ, Kiraz N, Erdal B, Gelgeç E, Erer A, Saraç Ö, Yavuz A, Dolap U, Hayri UB, Kocadelioğlu İ, Batmaz E. The incidence of acute kidney injury and its association with mortality in patients diagnosed with COVID‐19 followed‐up in intensive care unit. Ther Apher Dial 2022. Jan 6. doi: 10.1111/1744-9987.13790. Online ahead of print. [DOI] [PubMed] [Google Scholar]
  • 2. Sookaromdee P, Wiwanitkit V. Novel coronavirus infection (COVID‐19) and renal failure: an observation from cases in the 1(st) month of outbreak. Saudi J Kidney Dis Transpl. 2020;31(6):1455. [DOI] [PubMed] [Google Scholar]
  • 3. Sriwijitalai W, Wiwanitkit V. Coronavirus‐antibody immune complex: a nanostructure appraisal possible cause of nephropathology. Saudi J Kidney Dis Transpl. 2020;31(3):694–5. [DOI] [PubMed] [Google Scholar]
  • 4. Joob B, Wiwanitkit V. Blood viscosity of COVID‐19 patient: a preliminary report. Am J Blood Res. 2021;11(1):93–5. [PMC free article] [PubMed] [Google Scholar]

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