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. 2022 Apr 15:10.1111/tid.13835. Online ahead of print. doi: 10.1111/tid.13835

COVID‐19 in Vaccinated Versus Unvaccinated Hematologic Malignancy Patients

Catherine DeVoe 1,, Shraddha Pandey 1, Dayana Shariff 1, Shagun Arora 2, Timothy J Henrich 1,3, Deborah S Yokoe 1, Charles R Langelier 1,4, Venice Servellita 5, Charles Chiu 1,5, Steve Miller 5, Jennifer M Babik 1, Peter Chin‐Hong 1, Monica Fung 1,
PMCID: PMC9115335  PMID: 35426225

Abstract

The effect of vaccination on severity of subsequent COVID‐19 in patients with hematologic malignancies (HM) is unknown. In this single‐center retrospective cohort study, we found no difference in severity of COVID‐19 disease in vaccinated (n = 16) versus unvaccinated (n = 54) HM patients using an adjusted multiple logistic regression model. Recent anti‐B‐cell therapy was associated with more severe illness.

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Keywords: COVID‐19, breakthrough infection, hematologic malignancy


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