Correction to: Amino acid restriction alters survival mechanisms in pancreatic beta cells: possible role of the PI3K/Akt pathway

Correction to: European Journal of Nutrition (2021) 60:3947–3957 10.1007/s00394-021-02568-2

The original version of this article unfortunately contained a mistake. In Fig. 4C and D, the images marked C (control) and CW (control pretreated with Wortmannin) are the same.

The corrected Fig. 4 is given in the following page.

Fig. 4.

Evaluation of Akt/PI3K pathway in cell viability and redox balance. Cells were submitted to the treatment with Wortmannin during 30 min before the 48 h of amino acid restriction. a Protein content of pAkt/Akt in basal situation and b after its inhibition by different concentrations of Wortmannin (n = 4–6). c–f Representative images and percentage of apoptotic cells (g) costained with Hoechst 33,342 and propidium iodide, pictured and determined by the High Content Imaging System in ImageXpress Micro Confocal (n = 5). h Super-oxide content by DHE probe (n = 7). i H₂O₂ production by Amplex probe (n = 7). Cw and Rw correspond to C and R pre-treated with Wortmannin. Data are mean ± SEM and were submitted to Student t test for pAkt/Akt analyses, and to two-way ANOVA for Wortmannin analyses. *p < 0.05 effect of amino acid restriction and ^#p < 0.05 effect of Wortmannin