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. 2022 Sep 22;4:130. Originally published 2021 Dec 16. [Version 2] doi: 10.12688/hrbopenres.13400.2

Mental health following an initial period of COVID-19 restrictions: findings from a cross-sectional survey in the Republic of Ireland

Maria Isabela Troya 1,#, Mary Joyce 2,a,#, Ali Khashan 1, Claire Buckley 1, Kasturi Chakraborti 1, Philipp Hoevel 3, Rory Humphries 3, Patricia M Kearney 1, Elizabeth Kiely 4, Mike Murphy 5, Ivan Perry 1, Ella Arensman 1,2,6
PMCID: PMC9120930  PMID: 35633845

Version Changes

Revised. Amendments from Version 1

We have updated the manuscript in order to include the suggested revisions from the two peer reviewers. These changes include: Based on Reviewer 1 suggestions: 1. We have added the full acronym of the NSRF (National Suicide Research Foundation) acronym to paragraph 2 of the Methods section.   2. We have amended Table 1 to address the typing error whereby the % sign was included in seven cells in error.   3. We have removed the word “on” from the first paragraph of the Discussion section. Based on Reviewer 2 suggestions: 1. We have added to the Discussion section that our study would have benefitted from collecting data on personal efforts to socially isolate.  2. We have added to the Discussion section that levels of depression and anxiety in the Irish population may be underestimated due to non-participation bias. Please note that full description of comments to Reviewer 2 are also listed in the Response to Reviewers.

Abstract

Background: We assessed the mental health of individuals in the general population, during an initial period of easing of COVID-19 restrictions in the Republic of Ireland (RoI).

Methods: Data were collected through a nationally representative cross-sectional telephone survey, during the first period of easing of restrictions during the COVID-19 pandemic between May and July 2020. Mental health was examined using the Patient Health Questionnaire Anxiety Depression Scale. Poisson regression analyses were conducted to estimate risk ratios with robust variance estimation of the association between selected demographic factors and the risk of having depression and anxiety symptoms.

Results: Of the 1,983 participants, 27.7% (n = 549; 95% CI: 0.26 - 0.30) reported depression and anxiety symptoms, while 74 (3.8%; 95% CI: 0.03 - 0.05) disclosed self-harm and/or suicidal thoughts. Females (RR: 1.60, 95% CI: 1.37 - 1.87, p < 0.0005), employed individuals who experienced a change in work status (RR: 1.50, 95% CI: 1.24 - 1.82, p < 0.0005), participants cocooning due to a health condition (RR: 1.34, 95% CI: 1.08 - 1.66, p< 0.01), participants who were self-isolating (RR: 1.25, 95% CI: 1.03 - 1.51, p=0.025) and moderate-heavy drinkers (RR: 1.27, 95% CI: 1.09 - 1.47, p<0.01) were at increased risk of depression and anxiety. Young people aged 18-29 years and those in the two lowest income categories were most likely to report self-harm and/or suicidal thoughts.

Conclusion: As the COVID-19 pandemic continues, with further waves and associated restrictions, the impact on mental health in the population as a whole and in specific subgroups must be considered.

Study protocol registration: doi.org/10.12688/hrbopenres.13103.2

Keywords: Virus diseases; COVID-19; public health; public mental health; epidemiology; mental health

Introduction

Since the appearance of the coronavirus disease in 2019 (COVID-19) and the declaration of a global pandemic by the World Health Organisation in March 2020, individuals and societies have endured ongoing health and social impacts. The implementation of physical distancing interventions has been associated with an overall reduction in COVID-19 incidence worldwide 1 . Like other Western European countries, the Republic of Ireland (RoI) implemented, with high levels of public compliance, a range of restrictive public health measures in March 2020 to contain the spread of COVID-19 2 . These measures included closure of schools and third-level institutes, travel restrictions and physical distancing (see extended data). On the 18 th May 2020, these restrictions were eased 3 .

In addition to the physical health impacts and mortality associated with COVID-19, there have been concerns about the effects of physical distancing measures on individuals’ mental health 4, 5 . Several risk factors for mental health conditions and behaviours including self-harm were identified during the pandemic as a result of social restrictions, including isolation and loneliness, limited access to education and social support, and restricted access to healthcare services 46 . Emerging evidence indicates there may have been an increase in psychiatric symptoms and self-harm thoughts during the pandemic, particularly among people with pre-existing mental health conditions 79 . In a study conducted in RoI on 31 st March 2020 immediately after the announcement of social restrictions, it was found that 20.0 – 22.7% of participants had self-reported symptoms of depression or anxiety 10 . In a subsequent Irish study in which an online electronic questionnaire and telephone interviews were conducted between 23 rd April and 1 st May 2020, 26.6% of respondents reported feelings of loneliness, and 32.5% reported feeling downhearted or depressed 2 . No study has yet assessed the mental health of individuals in the general population during the period of easing of restrictions in the RoI (May to July 2020).

This study reports on the findings of a national household survey that aimed to assess the mental health of the Irish population during the initial period of easing of COVID-19 related restrictions in the RoI. Specifically, the study objectives were to estimate the prevalence of depression and anxiety symptoms, and thoughts of self-harm and/or suicide based on standardised, validated instruments, and to examine potential associations between selected socio-demographic characteristics and mental health symptomatology.

Methods

Ethics

The study received ethical approval from the Clinical Research Ethics Committee of the Cork Teaching Hospitals (Ref: EMC 4 (b)05/05/20). Participants were informed about the research study by the interviewer and verbal consent was obtained before proceeding with the survey. After completion of the survey, participants were advised that further information about the study was available online. Participants were provided with the necessary information to obtain additional information via websites. Respondents could also request these documents by email or post. Further information on ethical considerations and the informed consent process can be found in Troya et al. 11

As some interview questions had the potential to trigger emotional reactions for participants, training workshops were provided to interviewers in advance of data collection by psychologists from the National Suicide Research Foundation (NSRF) and UCC School of Applied Psychology (EA, MM, MIT). At the end of the survey, participants were provided with contact details of support organisations, where indicated. In cases where further follow-up was deemed necessary by the interviewer, phone calls to participants were conducted by the psychology team. In such instances, participants were required to give consent and contact details for a follow-up phone call.

Study design

This study is part of a larger study which aims to estimate the effects of public health measures in RoI during the COVID-19 pandemic 11 . The primary outcome was mental health measured through self-reported depression and anxiety symptoms. Secondary outcomes were thoughts of self-harm and/or suicide.

A nationally representative cross-sectional telephone survey was conducted to assess mental health of the Irish population. The survey was conducted during the start of the easing of restrictions. Survey one was administered between 26 th May - 17 th June 2020 and survey two between 1 st – 23 rd July 2020 12, 13 . The response rates were 43.6% for survey one and 26.3% for survey two. Response rates estimates included refusals and calls which were interrupted.

The marketing company Ipsos MRBI conducted the telephone survey in collaboration with the study authors. The study authors designed the survey and provided training to interviewers conducting the telephone survey to ensure a standardised interview and data collection approach.

A patient, who was one of the first cases of COVID-19 diagnosed and managed successfully in RoI contributed to the initial design of this study. The patient contributed to inclusion/exclusion of relevant data sources and measurements 11 .

Participants

Participants were randomly selected from the general population. The eligibility criteria were: (a) aged 18 years and above, (b) residing in RoI, (c) having a landline or mobile telephone number, and (d) providing consent. To achieve a nationally representative sample, surveys were conducted using random digit-dialling (approximately 80% mobile, 20% landline), with response rates estimates based on proportion of non-operational and non-answering numbers. A sample size of 1,000 participants, excluding non-responders, non-operational numbers and non-answering numbers, produced a two-sided 95% confidence interval (CI) with a width equal to 0.028 when the sample proportion is 0.05. We aimed to collect data on 1,000 participants during each of two survey iterations. Data were weighted by age, gender, and region, with population estimates based on the Irish Labour Force Survey 14 .

Data sources and measurement

Internationally validated instruments were used to measure primary and secondary outcomes. Symptoms of depression and anxiety in the previous two weeks were measured with the 16-item Patient Health Questionnaire Anxiety-Depression Scale (PHQ-ADS) 15 . The PHQ-ADS is comprised of the PHQ-9 and GAD-7 which measure depression and anxiety, respectively. Scores range from 0 to 48 and participants symptoms are categorised based on their scores. Participants who had scores categorised as mild, moderate, or severe symptoms of depression and anxiety measured by the PHQ-ADS (cut-off ≥10) were classified as experiencing mental health symptoms. Participants who reported a score of <10 were classified as not experiencing mental health symptoms. The internal reliability of the PHQ-ADS was high (Cronbach’s alpha=0.8 to 0.9) 15 . Within the PHQ-ADS, one item specifically assesses participants’ self-harm and/or suicidal thoughts in the previous two weeks.

As part of the wider survey, information on socio-demographic characteristics of participants was collected as well as questions about participants’ general health. Participants were also asked questions about cocooning during the pandemic. Cocooning was introduced for people who were advised to stay at home due to increased vulnerability. Measures at the time of this study involved staying at home and avoiding physical contact with others, limiting social interactions and staying within 2km radius of one’s home. Individuals aged 70 or more, as well as individuals who were at higher risk from COVID-19 including those with specific health conditions such as lung conditions, heart disease etc. were advised to cocoon 16 . A full list of survey questions can be found in Troya et al. 11 .

Relevant socio-demographic variables included in this study were gender, age group, level of education, net annual income, employment status, children under 18-years-old living in household, cocooning, and alcohol intake.

Statistical analyses

Statistical software package Stata 17 version 15.1 was used to assist in the data analysis. Descriptive statistics summarised selected socio-demographic characteristics, as well as proportions with and without (a) depression and anxiety symptoms, and (b) self-harm and/or suicidal thoughts. Socio-demographic factors were analysed using Chi-square test for categorical variables. Poisson regression analyses were conducted to estimate risk ratios and 95% CIs with robust variance estimation of the association between selected demographic factors (gender, age, change in employment status, household combined annual income, children under 18-years-old living in the household, cocooning, self-reported alcohol intake) and the risk of having depression and anxiety symptoms as measured by the PHQ-ADS. Because we expected the outcome measure to be common (>10%), we wanted to estimate the risk ratio, however, considering that log-linear binomial models often do not converge, which is a known problem with this model, we used Poisson models instead 18 . Poisson models were performed for depression and anxiety scores, and then for self-harm and/or suicidal thoughts, including all the socio-demographic variables. Given self-harm and/or suicidal thoughts was a rare outcome (n=74), we used the largest number of participants as a reference group: 50 to 69-year-olds and earners of €30,000 - 79,999. Survey commands were used and estimates were weighted to account for the survey sampling design. We repeated the Poisson models for each survey iteration separately to examine whether the results changed between May and July 2020. The significance levels were set at p < 0.05.

Results

A total of 1,983 participants took part in the survey during two iterations of data collected between May and July 2020 (survey one: n = 969; survey two: n = 1,014) 12 . Socio-demographic characteristics of participants are summarised in Table 1. There were a similar number of males and females (52.0% females, 95% CI: 0.50 - 0.54, n = 1,031) with participants ranging in age from 18–91 years, and a mean age of 47.28 (SD = 17.11). Over half of the sample resided in the region of Leinster, had completed third-level education, and were working as an employee.

Table 1. Socio-demographic characteristics of participants.

Survey 1 Survey 2 Survey 1 & 2
Frequency (%) Frequency (%) Frequency (%)
N = 969 N = 1,014 N = 1,983
Gender
    Male 466 (48.1) 482 (47.5) 948 (47.8)
    Female 501 (51.7) 530 (52.3) 1,031 (52.0)
    Other 2 (0.2) 2 (0.2) 4 (0.2)
Age group
    18–29 years 167 (17.2) 198 (19.5) 365 (18.4)
    30–39 years 167 (17.2) 160 (15.8) 327 (16.7)
    40–49 years 182 (18.8) 230 (22.7) 412 (20.8)
    50–59 years 157 (16.2) 150 (14.8) 307 (15.5)
    60–69 years 157 (16.2) 146 (14.4) 303 (15.3)
    70+ years 127 (13.1) 118 (11.6) 245 (12.4)
Area of residence
    Leinster 547 (56.4) 585 (57.7) 1,132 (57.1)
    Munster 266 (27.5) 247 (24.4) 513 (25.9)
    Connacht 104 (10.7) 126 (12.4) 230 (11.6)
    Ulster 49 (5.1) 55 (5.4) 104 (5.2)
Highest level of education
    Primary level 41 (4.2) 39 (3.8) 80 (4.0)
    Group/ Inter/ Junior certificate 76 (7.8) 76 (7.5) 152 (7.7)
    Leaving certificate 188 (19.4) 225 (22.2) 413 (20.8)
    Other second level/PLC certificate or similar 92 (9.5) 89 (8.8) 181 (9.1)
    Third level degree/postgraduate course 566 (58.4) 579 (57.1) 1,145 (57.7)
    Other/ don't know 6 (0.6) 6 (0.6) 12 (0.6)
Household situation
    Living alone 151 (15.6) 142 (14.0) 293 (14.8)
    2 or more sharing (not a couple) 121 (12.5) 105 (10.4) 226 (11.4)
    Couple with dependent children 267 (27.6) 310 (30.6) 577 (29.1)
    Couple with independent children (no dependent child) 164 (16.9) 167 (16.5) 331 (16.7)
    Couple with no children 156 (16.1) 168 (16.6) 324 (16.3)
    Lone parent with dependent children 31 (3.2) 33 (3.3) 64 (3.2)
    Lone parent with independent children (and no dependent child) 20 (2.1) 26 (2.6) 46 (2.3)
    Household with two or more family units living together 57 (5.9) 58 (5.7) 115 (5.8)
    Other/ don’t know 2 (0.2) 5 (0.5) 7 (0.4)
Work situation
    Working as employee (full-time or part-time) 500 (51.6) 529 (52.2) 1029 (51.9)
    Self-employed 90 (9.3) 100 (9.9) 190 (9.6)
    Unemployed/ seeking work 81 (8.4) 88 (8.7) 169 (8.5)
    Not working due to permanent illness/ disability 41 (4.2) 17 (1.7) 58 (2.9)
    Retired 186 (19.2) 194 (19.1) 380 (19.2)
    Full-time homemaker/ looking after family 29 (3.0) 32 (3.2) 61 (3.1)
    Student 34 (3.5) 51 (5.0) 85 (4.3)
    Other/don't know 8 (0.8) 3 (0.3) 11 (0.6)
Annual combined net income for household
    Under €19,999 115 (11.9) 111 (10.9) 226 (11.4)
    €20,000 to €29,999 109 (11.2) 91 (9.0) 200 (10.1)
    €30,000 to €49,999 227 (23.4) 193 (19.0) 420 (21.2)
    €50,000 to €79,999 206 (21.3) 230 (22.7) 436 (22.0)
    €80,000 or greater 128 (13.2) 152 (15.0) 280 (14.1)
    Don’t know/ refused to answer 184 (19.0) 237 (23.4) 421 (21.2)

Health related information

In terms of alcohol consumption, half of the sample (n = 992; 50.0%, 95% CI: 0.48 - 0.52) described themselves as occasional drinkers, while just over a quarter (n = 513; 25.9%, 95% CI: 0.24 - 0.28) classified themselves as ‘moderate’ drinkers and 32 (1.6%, 95% CI: 0.01 - 0.02) as ‘heavy’ drinkers. Close to one fifth of participants reported cocooning (i.e. avoiding contact with people to avoid risk of COVID-19) (n = 365; 18.4%, 95% CI: 0.16 - 0.19) with the most common reported reason being over 70 years old (n = 214; 10.8%, 95% CI: 0.09 - 0.12). For participants who cocooned because of a health condition (n = 151; 7.6%, 95% CI: 0.07 - 0.09), a severe respiratory condition was the most frequently cited condition (n = 50, 33.1%, 95% CI: 0.07 - 0.11).

Missing data

There were missing data for the PHQ-ADS for 22 (2.3%) participants in survey one, and for 19 (1.9%) participants in survey two. For the question on suicidal/self-harm thoughts, there were missing data for four (0.4%) participants in survey one, and two (0.3%) participants in survey two.

Mental health

Depression and anxiety symptoms. More than a quarter of participants (27.7%, 95% CI: 0.26 - 0.30, n = 549) reported symptoms of depression and anxiety as measured by the PHQ-ADS. Of the 549 participants who reported symptoms of depression and anxiety, 383 (69.8%, 95% CI: 0.18 - 0.22) reported mild symptoms, 118 (21.5%, 95% CI: 0.05 - 0.07) reported moderate symptoms and 48 (8.7%, 95% CI: 0.02 - 0.03) reported severe symptoms. The prevalence of depression and anxiety symptoms was similar for survey one (n = 270, 28.5%; 95% CI: 0.26 - 0.32) and survey two (n = 279, 28%; 95% CI: 0.25 - 0.31). Table 2 presents an overview of the number of participants in each PHQ-ADS category as well as a breakdown according to relevant socio-demographic variables.

Table 2. Binary classification of PHQ-ADS scores by socio-demographic characteristics for all participants.

Minimal
(PHQ-ADS < 10)
Mild or more
(PHQ-ADS ≥ 10)
Gender (n = 1,393) (n = 549)
    Male 733 (52.6%) 194 (35.3%)
    Female 659 (47.3%) 353 (64.3%)
    Other 1 (0.1%) 2 (0.4%)
Age group (n=1378) (n=541)
    18–29 years 201 (14.6%) 159 (29.4%)
    30–39 years 213 (15.5%) 108 (20.0%)
    40–49 years 293 (21.3%) 109 (20.1%)
    50–59 years 237 (17.2%) 66 (12.2%)
    60–69 years 242 (17.6%) 53 (9.8%)
    70+ years 192 (13.9%) 46 (8.5%)
Highest level of education (n=1393) (n=549)
    Primary level 52 (3.7%) 21 (3.8%)
    Group/ inter/ junior certificate 107 (7.7%) 37 (6.7%)
    Leaving certificate 280 (20.1%) 128 (23.3%)
    Other second level/PLC certificate or similar 132 (9.5%) 45 (8.2%)
    Third level degree/postgraduate course 814 (58.4%) 316 (57.6%)
    Other 8 (0.6%) 2 (0.4%)
Annual combined net income for household (n=1393) (n=549)
    Under €19,999 146 (10.5%) 73 (13.3%)
    €20,000 to €29,999 136 (9.8%) 58 (10.6%)
    €30,000 to €49,999 305 (21.9%) 111 (20.2%)
    €50,000 to €79,999 318 (22.8%) 111 (20.2%)
    €80,000 or greater 217 (15.6%) 60 (10.9%)
    Don’t know/ refused to answer 271 (19.5%) 136 (24.8%)
Change in employment (n=1393) (n=549)
    No change 520 (37.3%) 136 (24.8%)
    Change 370 (26.6%) 170 (31.0%)
    Not applicable 503 (36.1%) 243 (44.3%)
Children <18 in household (n=1393) (n=549)
    No 963 (69.1%) 352 (64.1%)
    Yes 430 (30.9%) 197 (35.9%)
Cocooning (n=1393) (n=549)
    Not cocooning 1007 (72.3%) 376 (68.5%)
    Over 70 years old 163 (11.6%) 51 (8.8%)
    Health condition 96 (6.9%) 55 (9.5%)
    Self-isolating 126 (9.0%) 75 (13.0%)
Alcohol intake (n=1393) (n=549)
    None/ occasional drinker 1015 (72.9%) 389 (70.9%)
    Moderate/ heavy drinker 378 (27.1%) 160 (29.1%)

Findings from the Poisson regression analysis indicated that there was a significantly higher risk for females reporting symptoms of depression and anxiety than males, RR: 1.60 (1.37 - 1.86) (see Table 3). Individuals who had previously been employed or self-employed and had experienced a change in their work status had a significantly higher risk for symptoms of depression and anxiety than those for whom there was no change, RR: 1.50 (1.23 - 1.82). There was a significantly higher risk for symptoms of depression and anxiety for participants who were cocooning because of a health condition, RR: 1.33 (1.07 - 1.65), and participants who were self-isolating, RR: 1.24 (1.02 - 1.50). Lastly, participants who classified themselves as ‘moderate’ or ‘heavy’ drinkers were at a significant higher risk for mild or more severe symptoms of depression and anxiety, RR: 1.26 (1.08 - 1.47).

Table 3. Risk (RR) for having ‘mild or greater’ symptoms of depression and anxiety as per the PHQ-ADS.

Crude Adjusted
Predictor variable RR (95% CI) P value RR (95% CI) P value
Gender
    Male Reference [1.00] Reference [1.00]
    Female 2.023 (1.64, 2.48) <0.0001 1.60 (1.37, 1.86) <0.0001
Age
    18–29 years Reference [1.00] Reference [1.00]
    30–39 years 0.640 (0.46, 0.87) 0.005 0.89 (0.73, 1.09) 0.267
    40–49 years 0.470 (0.34, 0.63) <0.0001 0.69 (0.56, 0.85) 0.001
    50–59 years 0.352 (0.24, 0.49) <0.0001 0.50 (0.39, 0.64) <0.0001
    60–69 years 0.276 (0.19, 0.39) <0.0001 0.32 (0.24, 0.43) <0.0001
    70+ years 0.302 (0.20, 0.44) <0.0001 0.24 (0.14, 0.40) <0.0001
Education
    Primary level Reference [1.00] Reference [1.00]
    Junior certificate 0.856 (0.45, 1.60) 0.629 0.70 (0.43, 1.15) 0.168
    Leaving certificate 1.131 (0.65, 1.95) 0.658 0.72 (0.46, 1.12) 0.156
    Other secondary level 0.844 (0.45, 1.55) 0.586 0.58 (0.36, 0.94) 0.029
    Third level/PG course 0.961 (0.56, 1.62) 0.882 0.67 (0.43, 1.05) 0.085
    Don’t know/ refused 0.619 (0.12, 3.16) 0.564 0.58 (0.15, 2.16) 0.425
Income
    Under €19,999 Reference [1.00] Reference [1.00]
    €20,000 – €29,000 0.852 (0.56, 1.29) 0.454 1.01 (0.76, 1.33) 0.934
    €30,000 – €49,000 0.727 (0.51, 1.03) 0.08 0.87 (0.67, 1.13) 0.318
    €50,000 – €79,000 0.698 (0.48, 0.99) 0.047 0.82 (0.63, 1.08) 0.171
    €80,000 or greater 0.552 (0.37, 0.82) 0.004 0.66 (0.48, 0.91) 0.011
    Don’t know/ refused 1.003 (0.70, 1.42) 0.983 0.89 (0.70, 1.14) 0.386
Change in employment (for those employed)
    No change Reference [1.00] Reference [1.00]
    Change 1.756 (1.35, 2.28) <0.0001 1.50 (1.23, 1.82) <0.0001
    Not applicable 1.847 (1.44, 2.35) <0.0001 1.68 (1.37, 2.05) <0.0001
Children <18 in household
    No Reference [1.00] Reference [1.00]
    Yes 1.253 (1.01, 1.54) 0.033 1.03 (0.88, 1.20) 0.69
Cocooning
    Not cocooning Reference [1.00] Reference [1.00]
    Over 70 years old 0.777 (0.54, 1.09) 0.153 1.57 (0.97, 2.56) 0.064
    Health condition 1.506 (1.05, 2.14) 0.023 1.33 (1.07, 1.65) 0.009
    Self-isolating 1.521 (1.11, 2.08) 0.009 1.24 (1.02, 1.50) 0.025
Alcohol intake
    None/occasional drinker Reference [1.00] Reference [1.00]
    Moderate/heavy drinker 1.104 (0.88, 1.37) 0.373 1.26 (1.08, 1.47) 0.002

Suicidal or self-harm thoughts. When asked about suicidal or self-harm thoughts in the previous two weeks, 3.8% of the participants (n = 74, 95% CI: 0.03 - 0.05) reported that they had experienced these thoughts on at least a few days during this timeframe. In survey one, 3.3% (n = 32; 95% CI: 0.02 - 0.05) participants reported thoughts of self-harm and/or suicide in the past two weeks, while this number had increased to 4.2% in survey two (n = 42; 95% CI: 0.03 - 0.06). Of those reporting suicidal thoughts, the percentage breakdown of females was greater than that reported in the full sample (56.7% vs 52%) (see Table 4). This was also the case for participants aged 18–29 years (45.1% vs 18.4%), those earning under €19,999 (18.9% vs 11.4%), and those cocooning (32.4% vs 28.8%). Individuals aged 18 – 29 years were more likely to have suicidal and/or self-harm thoughts as opposed to 50 – 69-year-olds (RR: 3.41; 95% CI: 1.86 - 6.22) (see Table 5). Participants in the two lowest income categories (<€19,999 and €20,000–29,999) were more likely to have suicidal and/or self-harm thoughts than those earning €30,000–79,999 (RR: 2.84; 1.33 – 6.03, and RR: 2.22; 1.03 – 4.80).

Table 4. Sociodemographic characteristics of participants reporting self-harm/suicidal ideation.

Participants
reporting self-harm/
suicidal ideation
( n = 74)
Total
Participants
(n= 1983)
Gender
   Male
   Female
   Other
30 (40.5%)
42 (56.7%)
2 (2.8%)
948 (47.8%)
1031 (52.0%)
4 (0.2%)
Age Group
   18–29 years
   30–39 years
   40–49 years
   50–59 years
   60–69 years
   70 years +
( n=71)
32 (45.1%)
8 (11.3%)
10 (14.1%)
7 (9.8%)
10 (14.1%)
4 (5.6%)

365 (18.4%)
327 (16.7%)
412 (20.8%)
307 (15.5%)
303 (15.3%)
245 (12.4%)
Highest Level of Education
   Primary Level
   Group/ Inter/ Junior Certificate
   Leaving Certificate
   Other Second Level/PLC Cert or similar
   Third Level Degree/Postgraduate Course
   Other
( n=74)
5 (6.8%)
5 (6.8%)
21 (28.4%)
8 (10.8%)
35 (47.3%)
0 (0%)

80 (4.0%)
152 (7.7%)
413 (20.8%)
181 (9.1%)
1145 (57.7%)
12 (0.6%)
Annual Combined Net Income
   Under €19,999
   €20,000 to €29,999
   €30,000 to €79,999
   €80,000 or greater
   Don’t know/ Refused to answer
( n=74)
14 (18.9%)
9 (12.2%)
20 (27.0%)
5 (6.8%)
26 (35.1%)

226 (11.4%)
200 (10.1%)
856 (43.2%)
280 (14.1%)
421 (21.2%)
Change in Employment
   No change
   Change
   Not applicable
( n=74)
17 (23.0%)
22 (29.7%)
35 (47.3%)

666 (33.6%)
551 (27.8%)
766 (38.6%)
Children <18 in household
   No
   Yes
( n=74)
56 (75.7%)
18 (24.3%)

1345 (67.8%)
638 (32.2%)
Cocooning
   No
   Yes
( n=74)
50 (67.6%)
24 (32.4%)

1412 (71.2%)
567 (28.8%)
Alcohol Intake
   None/ Occasional drinker
   Moderate/ Heavy drinker
( n=74)
59 (79.7%)
15 (20.2%)

1438 (72.5%)
545 (27.5%)

Table 5. Risk (RR) for having self-harm and/or suicidal ideation in the past two weeks.

Crude Adjusted
Predictor variable Number
of cases
RR (95% CI) P value RR (95% CI) P value
Gender
    Male 30 Reference [1.00] Reference [1.00]
    Female 42 1.298 (0.805, 2.091) 0.284 1.321 (0.84, 2.05) 0.216
Age
    18–29 years 32 3.346 (1.830, 6.118) <0.0001 3.405 (1.86, 6.22) <0.0001
    30–39 years 8 0.876 (0.374, 2.052) 0.761 1.410 (0.57, 3.45) 0.451
    40–49 years 10 0.873 (0.396, 1.926) 0.736 1.495 (0.64, 3.47) 0.349
    50–69 years 17 Reference [1.00] Reference [1.00]
    70+ years 4 0.580 (0.193, 1.743) 0.332 0.517 (0.14, 1.84) 0.31
Education
Secondary level or less 39 Reference [1.00] Reference [1.00]
Third level/PG course 35 0.636 (0.399, 1.013) 0.057 0.796 (0.47, 1.32) 0.38
Income
    Under €19,999 14 2.78 (1.381, 5.596) 0.004 2.844 (1.33, 6.03) 0.007
    €20,000 – €29,000 9 1.965 (0.881, 4.383) 0.099 2.223 (1.03, 4.79) 0.042
    €30,000 – €79,000 20 Reference [1.00] Reference [1.00]
    €80,000 or greater 5 0.761 (0.283, 2.047) 0.588 0.842 (0.32, 2.22) 0.729
    Don’t know 26 2.759 (0.015, 0.037) 0.001 2.174 (1.20, 3.91) 0.01
Change in employment (for those employed)
    No change 17 Reference [1.00] Reference [1.00]
    Change 22 1.597 (0.839, 3.038) 0.154 1.305 (0.68, 2.47) 0.414
    Not applicable 35 1.838 (1.020, 3.312) 0.043 1.066 (0.56, 2.01) 0.843
Children <18 in house
    No 56 Reference [1.00] Reference [1.00]
    Yes 18 0.669 (0.390, 1.148) 0.145 0.697 (0.38, 1.25) 0.232
Cocooning/self-isolating
    No 50 Reference [1.00] Reference [1.00]
    Yes 24 1.210 (0.736, 1.989) 0.452 1.302 (0.76, 2.23) 0.336
Alcohol intake
    None/occasional drinker 59 Reference [1.00] Reference [1.00]
    Moderate/heavy drinker 15 0.662 (0.372, 1.176) 0.16 0.887 (0.50, 1.55) 0.679

Discussion and conclusions

This research is amongst the first nationally representative studies to report on mental health during a period of easing of COVID-19 related restrictions. Whilst research on COVID-19 and its long-term impacts continue, this study adds to the data on self-reported mental health outcomes of a nationally representative population in RoI. Over a quarter of participants (27.7%) reported symptoms of depression and anxiety. Females, young people aged 18–29, those who experienced a change in their work situation, moderate to heavy drinkers, individuals cocooning due to health conditions and self-isolating, and those who report moderate to heavy drinking, were at increased risk of adverse mental health outcomes. Young people aged 18–29 and low-income earners (<€29,999) had a higher risk of experiencing self-harm or suicidal thoughts when compared to 50–69 year olds and €30,000–79,999 income earners.

In RoI, findings from the Healthy Ireland 2018 survey, a national representative survey, reported rates of 6% of self-reported depression and anxiety before the COVID-19 pandemic 19 . During the first week of the implementation of movement restrictions measures (31 st March 2020) in RoI, Hyland et al. found 20 - 22.7% of participants had self-reported symptoms of depression or anxiety 10 . In that early study, females and young people aged 18-34 had higher levels of mental health symptoms 10 . The findings from the current study, which used the same measurement instrument (PHQ-ADS), and was conducted between May and July 2020, suggest that levels of anxiety and depression may have increased during the period of intense public health restrictions. Given the timeframe for this study, this apparent increase did not immediately resolve with the official loosening of restrictions which took place at the end of June in the RoI. In that context, it is worth considering that the overall impact of COVID-19 may have had an impact on individuals’ depression and anxiety symptoms. Females and young people have also been found to be at increased risk for mental health symptoms in other countries including the United Kingdom 10, 20 , Germany 21 and Ecuador 22 .

Findings suggest that individuals who were cocooning due to a health condition had increased risk of mental health symptoms, as well as those who were self-isolating for other reasons. Being over the age of 70 was not associated with poorer mental health outcomes. While participants over the age of 70 who were cocooning reported poorer mental health outcomes (RR: 1.57), these findings were not statistically significant (p = 0.064). In other countries, including the Netherlands and United States, increased mental health symptoms were reported in this age group, including an increase in feelings of loneliness 23, 24 . As the COVID-19 pandemic continues, government advice for older people to self-isolate requires careful calibration given the potential long-term effects on older people’s mental health, including risk of self-harm 25 .

The RoI implemented public health measures that were broadly similar to those implemented in other Western European countries aligned with WHO recommendations and most recent evidence 1 . Broadly similar levels of mental health symptoms (anxiety and depression) associated with the pandemic and public health restrictions have been reported in the UK (21.0% – 26.1%) 20, 26 , Italy (17.0% – 20.0%) 27 Germany (14.0% – 44.0%) 21 , Austria (19.0% – 21.0%) 28 , and Australia (21.0 – 27.6%) 29 . Findings from other countries, such as China (28.0% – 35.0%) 30, 31 and Bangladesh (33.0% – 57.0%) 32 , indicate higher levels of anxiety and depression.

This study is among the first to measure the prevalence of self-harm and/or suicidal thoughts in a national general population sample during a period of easing of restrictions of the COVID-19 pandemic. We found that 3.7% of the population reported these thoughts during the initial period of easing of public health restrictions. Another study conducted in the UK with 3,077 participants recruited through an online survey found higher rates of self-harm and/or suicidal thoughts compared to our study and found that they increased over time: survey one (31 st March to 9 th April 2020): 8.2%, survey two (10–27 th April 2020): 9.2%, and survey three (28 th April to 11 th May 2020): 9.8% 20 . Studies conducted prior to the COVID-19 pandemic have found similar rates whereby a meta-analysis of data from multiple European countries reported a 12-month prevalence of 2.9% 33 . We therefore do not have evidence from the current study that thoughts of self-harm and/or suicide have increased during the first six months of the COVID-19 pandemic, but we should note the relative imprecision with which this rare outcome is estimated in the current study. The findings on socio-demographic factors associated with thoughts of self-harm and/or suicide with increased risk in younger people (aged 18 – 29 years) and low-income earners, are consistent with findings from the National Self-Harm Registry Ireland 34 . Thousands of Irish citizens were also in receipt of the COVID-19 unemployment payment due to the closure of businesses which may have led to financial and employment concerns 35 .

This is the first nationally representative study based on telephone interviews which assesses mental health during the period May to July 2020; a period of easing of COVID-19 related restrictions in RoI. The study reports on individuals’ experiences of the pandemic during the two-month period of easing of restrictions, using standardised tools with high retest-test reliability and internal consistency. As the COVID-19 pandemic continues, and further waves of public health measures are implemented by governments worldwide, there is a clear need for additional and ongoing work, including longitudinal studies on the impact of these measures on individuals’ mental health. Policymakers and clinicians should take note of the groups at higher risk of poor mental health outcomes and target their resources and support accordingly. There is evidence that interventions delivered in primary care and online interventions can aid in the treatment and support of individuals with mental health symptoms associated with the COVID-19 pandemic, including depression, anxiety, and suicidality 3638 .

Given the cross-sectional design, the issue of reverse causation should be considered in the interpretation of the findings 39 . The response rate for the first survey was relatively high for a population based survey at 43.6%. The rate for the second survey was lower at 26.3%. It is unclear why this disparity occurred between the two waves of data collection which took place within a relatively short timeframe and involved the same team of trained interviewers. One possible explanation is that survey two occurred during a period of further easing of restrictions which may have impeded individuals’ time and availability to respond to a telephone survey. Furthermore, non-participation bias must be considered, given that participation in this study relied on participants answering their telephone and talking about their mental health without prior notice. As a result, levels of depression and anxiety could have been underestimated due to non-participation bias. The study included a wide variety of questions, however, there was certain relevant information that was not recorded such as ethnicity.

A limitation of this study is that it does not include data on personal efforts to socially isolate which varied greatly across individuals. Although this study took place during an initial period of easing of restrictions, it is possible that many individuals were maintaining restrictions in their own lives. Future surveys should include questions about engagement in protective and risky behaviours and their associations with depression and anxiety. The high socioeconomic status of the sample, as indexed by >50% of the sample having completed third-level education and the majority being employed is also a limitation because the effects of the pandemic were not felt equally across socioeconomic strata. It would be helpful to conduct additional studies to examine levels of depression and anxiety across socioeconomic strata, and in urban versus rural samples. In further work, it will also be important to assess the potential impact of the pandemic on ethnic minorities, given the evidence of increased morbidity and mortality associated with COVID-19 in these vulnerable groups 4042 . Considering the ongoing impact of the COVID-19 pandemic, future research may wish to follow a nationally representative cohort of participants to examine further mental health impacts of the movement restriction measures of the pandemic. Despite the large sample size in the current study, we examined a relatively rare outcome (self-harm and/or suicidal thoughts) with only 74 observations. Future research with a larger sample size could further examine vulnerable groups at risk of self-harm and/or suicidal thoughts. Lastly, qualitative research could help to explore in further detail the impact of the pandemic on individuals’ mental health and examine strategies to address such impacts.

Acknowedgments

We would like to thank Ipsos MRBI for conducting the survey interviews. We would also like to thank study collaborators Mary Spillane, Dr Kieran Mulchrone, Prof Sebastian Wieczorek, and Prof Michael O’Riordain.

Funding Statement

Health Research Board: COV19-2020-117

The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

[version 2; peer review: 2 approved]

Data availability

Underlying data

Zenodo: COVID-19: Estimating the burden of symptomatic disease in the community and the impact of public health measures on physical, mental and social wellbeing https://doi.org/10.5281/zenodo.5650852 12

This study contains the following underlying data:

  • -

    NHS_Survey1.sav

  • -

    NHS_Survey2.sav

Extended data

Harvard Dataverse: Questionnaires for Surveys WP1 and WP2.

https://doi.org/10.7910/DVN/EKUTFF 13

This study contains the following extended data:

  • Survey 1 questionnaire in DOCX format (Appendix I)

  • Survey 2 questionnaire in DOCX format (Appendix II)

This study also contains the following associated data:

Zenodo: Timeline of public health measures in Ireland during March - July 2020 https://doi.org/10.5281/zenodo.5777656

Data are available under the terms of the Creative Commons Attribution 4.0 International.

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HRB Open Res. 2022 May 19. doi: 10.21956/hrbopenres.14598.r31874

Reviewer response for version 1

Aoife O'Donovan 1

This study examines mental health in Ireland between May and July 2020, an early phase of the COVID-19 pandemic when Ireland had recently removed strong restrictions on social activities. In this nationally representative study, 27.7% of participants reported clinically significant symptoms of depression and anxiety. The authors compare their results to those obtained in similar studies from March to May 2020 when strict restrictions were in place. In these earlier studies, 20-32% of individuals reported symptoms of depression and/or anxiety. Comparing these data to those collected prior to the pandemic, it appears that levels of depression and anxiety increased with the onset of the COVID-19 pandemic and did not immediately resolve with the official loosening of restrictions.

One major strength of this study is that it was designed to be nationally representative with participants selected at random from the general population of Ireland. However, due to the relatively modest response rates, the sample is skewed towards a more highly educated and employed sample. Another strength is the use of validated instruments for depression and anxiety (PHQ-9 and GAD-7). One limitation is that the study does not include data on personal efforts to socially isolate, which varied greatly across individuals. Although restrictions were loosened at the time of these surveys, it is possible that many individuals were maintaining restrictions in their own lives. Future surveys should include questions about engagement in protective and risky behaviors and their associations with depression and anxiety.

The investigators employed a telephone survey to collect all data, with surveys conducted roughly one month apart. Unfortunately, but as is common in such studies, the response rate was modest at 44% for survey 1 and 26% for survey 2. It is likely that there was selective non-participation, such that the current results may underestimate levels of depression and anxiety in the population.

A small percentage of the sample reported self-harm or suicidal thoughts in survey 1 (n=32) and survey 2 (n=42). The investigators employed the largest group of participants, 50 to 69-year-olds and earners of €30,000-79,999 as reference groups for analyses involving self-harm and/or suicidal thoughts. However, it might have been more informative to simply describe the characteristics of this small group of individuals compared to the rest of the sample. As it stands, the compelling conclusion that young people and low-income earners had higher rates of self-harm/suicidal thoughts only applies to the comparison with middle-aged and middle-income earners. Future studies should pick up on this important issue and identify sociodemographic and economic predictors of self-harm and suicidal thoughts during the pandemic.

The high socioeconomic status of the sample, as indexed by >50% of the sample, having completed third-level education and the majority being employed, is a limitation because the effects of the pandemic were not felt equally across socioeconomic strata. It would be helpful to conduct additional studies to examine levels of depression and anxiety across the socioeconomic strata, in urban versus rural samples, and as the authors point out, in different ethnic and racial groups.

Overall, this project is a representation of exactly the kind of work that needs to happen to ensure a data-based approach to managing the mental health effects of infectious disease pandemics. It is interesting that the investigators conducted their work during a relative easing of pandemic-related restrictions. Their findings indicate that the increase in depression/anxiety that occurred with the onset of the pandemic was not resolved immediately with the loosening of restrictions. These important findings need to be further elucidated and tested over time to inform public mental health campaigns.

Is the work clearly and accurately presented and does it cite the current literature?

Yes

If applicable, is the statistical analysis and its interpretation appropriate?

Yes

Are all the source data underlying the results available to ensure full reproducibility?

Yes

Is the study design appropriate and is the work technically sound?

Yes

Are the conclusions drawn adequately supported by the results?

Yes

Are sufficient details of methods and analysis provided to allow replication by others?

Yes

Reviewer Expertise:

Health Psychology, Psychoneuroimmunology

I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard.

HRB Open Res. 2022 Sep 2.
Mary Joyce 1

We thank the reviewer for their time reviewing our manuscript and the constructive feedback provided, as well as highlighting the study’s strengths, limitations, and main findings. We have addressed the reviewer’s comments below:

  1. We agree with the reviewer that our study would have benefited from gathering further information on personal efforts to socially isolate as well as engagement in protective and risk behaviours. Future research would benefit from incorporating these questions into their studies. We have now noted this in the Discussion section (see paragraph 8).

  2. The reviewer suggests that there may be selective non-participation via the telephone survey and therefore the results may underestimate levels of depression and anxiety in the population. Whilst we acknowledge that our sample may be biased towards people who answer telephone calls, we included both landline (20%) and mobile phone (80%) numbers to obtain the best possible representation. We used the best study design available to us during a pandemic, which did have its limitations, but which aimed to obtain a representative national sample. It could be possible that levels of depression and anxiety in the Irish population are underestimated due to non-participation bias. This had been outlined in the Discussion section and is now further highlighted based on this feedback (paragraph 7).

  3. The reviewer suggests that it might have been more informative to describe the characteristics of the small group of individuals who reported self-harm/suicidal thoughts compared to the rest of the sample. To address this point, we have now included an additional table in the Results section to further describe the characteristics of those reporting self-harm/suicidal thoughts in comparison to the full sample (Table 4).

    For this analysis of individuals reporting self-harm or suicidal thoughts, we used the largest number of participants as a reference group: those aged 50-69 years old and €30,000 - 79,999 income earners. We acknowledge the reviewer’s point outlining that these results conclude that young people and low-income earners had higher rates of self-harm/suicidal thoughts only when applied to the comparison with middle-aged and middle-income earners. We have edited the manuscript to reiterate this point in the Discussion (paragraph 1).

  4. Our study used random selection to recruit participants, however we did have modest response rates as highlighted by the reviewer. It is suggested by the reviewer that the sample may be skewed towards a more highly educated and employed sample as a consequence. Although we obtained modest response rates, we do not believe this to be the case. Our study sample had the following characteristics: 52% female, 53% aged between 30-59, 57.7% having completed third-level education, and 61.5% employed or self-employed (Troya et al., 2021). According to the most recent statistics from the Central Statistics Office (CSO, 2021a), third-level education is completed by 51% of Irish adults as of 2020, and 63.2% were employed in 2020 (CSO, 2021b). Given the similarities in the distribution of gender, age, education, and employment status between our sample and the national demographic profile of adults in Ireland, we believe that our sample could be considered nationally representative. In consideration of any potential skewness in the sample, data were also weighted by age, gender, and region with population estimates based on the Irish Labour Force Survey.

    While we believe that our sample could be considered nationally representative, we agree with the reviewer that the effects of the pandemic were not felt equally across socioeconomic strata. We agree that it would be helpful to conduct additional studies across socioeconomic strata, such as in urban versus rural samples, and have added this to paragraph 8 of the Discussion section.

References

Central Statistics Office. 2021a. Accessed June 21, 2022 from https://www.cso.ie/en/releasesandpublications/ep/p-eda/educationalattainmentthematicreport2020/

Central Statistics Office. 2021b. Labour Force Survey Quarter 2 2021. Accessed June 21, 2022 from https://www.cso.ie/en/releasesandpublications/ep/p-lfs/labourforcesurveyquarter22021/employment/

HRB Open Res. 2022 Mar 1. doi: 10.21956/hrbopenres.14598.r31513

Reviewer response for version 1

John R Kelly 1,2

Troya and colleagues present findings from a nationally representative cross-sectional telephone survey, using the Patient Health Questionnaire Anxiety-Depression Scale, during a period of easing of COVID-19 related restrictions in the Republic of Ireland.

This is a useful survey and very well written.  

I have only 3 very minor comments to make.

  1. Methods: In paragraph 2, line 3. I recommend adding “National Suicide Research Foundation” (NSRF).

  2. Table 1: Why do only 7 boxes have the % sign? Survey 1 column, gender, other, and then in the last 3 rows. Perhaps, there is no need for the % sign.

  3. Discussion: In paragraph 1, line 3: “Whilst research into on COVID-19”. No need for on.

In summary, this is a very clear and well-written survey, which adds to the existing research on the mental health impact of COVID-19.

Is the work clearly and accurately presented and does it cite the current literature?

Yes

If applicable, is the statistical analysis and its interpretation appropriate?

Yes

Are all the source data underlying the results available to ensure full reproducibility?

Yes

Is the study design appropriate and is the work technically sound?

Yes

Are the conclusions drawn adequately supported by the results?

Yes

Are sufficient details of methods and analysis provided to allow replication by others?

Yes

Reviewer Expertise:

Psychiatry

I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard.

HRB Open Res. 2022 Sep 2.
Mary Joyce 1

We thank the reviewer for their time reviewing our manuscript and the helpful feedback provided. We have addressed the reviewer’s comments and incorporated them into our manuscript as evidenced below.  

  1. We have added the full acronym of the NSRF (National Suicide Research Foundation) acronym to paragraph 2 of the Methods section.  

  2. We have amended Table 1 to address the typing error whereby the % sign was included in seven cells in error.  

  3. We have removed the word “on” from the first paragraph of the Discussion section. 

Associated Data

    This section collects any data citations, data availability statements, or supplementary materials included in this article.

    Data Citations

    1. Troya IM, Joyce M, Khashan A, et al. : COVID-19: Estimating the burden of symptomatic disease in the community and the impact of public health measures on physical, mental and social wellbeing.(Original) [Data set]. Zenodo. 2021. 10.5281/zenodo.5650852 [DOI] [PMC free article] [PubMed]

    Data Availability Statement

    Underlying data

    Zenodo: COVID-19: Estimating the burden of symptomatic disease in the community and the impact of public health measures on physical, mental and social wellbeing https://doi.org/10.5281/zenodo.5650852 12

    This study contains the following underlying data:

    • -

      NHS_Survey1.sav

    • -

      NHS_Survey2.sav

    Extended data

    Harvard Dataverse: Questionnaires for Surveys WP1 and WP2.

    https://doi.org/10.7910/DVN/EKUTFF 13

    This study contains the following extended data:

    • Survey 1 questionnaire in DOCX format (Appendix I)

    • Survey 2 questionnaire in DOCX format (Appendix II)

    This study also contains the following associated data:

    Zenodo: Timeline of public health measures in Ireland during March - July 2020 https://doi.org/10.5281/zenodo.5777656

    Data are available under the terms of the Creative Commons Attribution 4.0 International.


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