In the original article, there was a mistake in Figure 1 as published. IL-2 and IFN-γ was originally described as a soluble factor released by CD4+ Th2. This should be changed to “IL-10 was described as a soluble factor released by CD4+ Th2 cells that can preclude the release of CD4+ Th1 cytokines, such as IL-2 and IFN-γ.” The corrected Figure 1 appears below.
Figure 1.
Role of IL-10 in VEO-IBD. IL-10 is released by CD4+Th2 cells and inhibits the release of cytokines such as IL-2 and IFN-γ. IL-10 inhibits the release of inflammatory cytokines and the inflammatory response. Shp2 can reduce the sensitivity of macrophages to IL-10 and produce proinflammatory effects.
In the original article, there was an error in Immune Dysregulation, “Cytokines and Their Receptors.” “IL-10 was originally described as a soluble factor released by CD4+ Th2 cells that can preclude the release of CD4+ Th4 cytokines, such as IL-2 and IFN-γ (22) (Figure 1)” has been corrected to “IL-10 was originally described as a soluble factor released by CD4+ Th2 cells that can preclude the release of CD4+ Th1 cytokines, such as IL-2 and IFN-γ (22) (Figure 1).”
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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References
- 22.Fiorentino DF, Bond MW, Mosmann TR. Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med. (1989) 170: 2081–95. 10.1084/jem.170.6.2081 [DOI] [PMC free article] [PubMed] [Google Scholar]

