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The figure describes diagnostic tools, both the imaging techniques and biomarkers for small-vessel disease, and the current therapeutic approach. CAD, coronary artery disease; CRP, C-reactive protein; CT, computed tomography; FLAIR-MRI, fluid-attenuated inversion recovery magnetic-resonance imaging; MRI, magnetic-resonance imaging; PET, positron-emission tomography; TNF-α, tumor-necrosis-factor α; IL-6, interleukin.
