Table 2 –
Burden of MAP deviation from MAPopt, index of impaired CAR, and StO2 on Day 1 after cardiac arrest.
| Cerebral physiology parameter Median [IQR] |
Favorable (n = 10) | Unfavorable (n = 24) | p-value |
|---|---|---|---|
|
| |||
| MAP < MAPopt−5 | |||
| Magnitude MAP below MAPopt − 5 (mmHg) | 9 [8, 10] | 13 [11, 17] | 0.01 |
| Percent time MAP < MAPopt−5 (%) | 24 [14, 28] | 38 [26, 61] | 0.03 |
| Burden MAP < MAPopt−5 (mmHg*Min/Hr) | 62 [43, 102] | 187 [107, 318] | 0.01 |
| MAP within ± 5 of MAPopt | |||
| Percent time MAP within ± 5 of MAPopt (%) | 36 [28, 40] | 31 [17, 43] | 0.30 |
| MAP > MAPopt + 5 | |||
| Magnitude MAP above MAPopt + 5 (mmHg) | 12 [10, 12] | 12 [9, 15] | 0.83 |
| Percent time MAP > MAPopt + 5 (%) | 36 [27, 44] | 21 [13, 38] | 0.07 |
| Burden MAP > MAPopt + 5 (mmHg*Min/Hr) | 272 [198, 306] | 207 [92, 295] | 0.14 |
| COx | |||
| COx | 0.06 [−0.01, 0.20] | 0.08 [−0.00, 0.20] | 0.92 |
| Percent time COx ≥ 0.3 (%) | 25 [19, 42] | 32 [19, 44] | 0.78 |
| Percent COx burden ≥ 0.3 (%) | 8 [4, 16] | 10 [5, 16] | 0.66 |
| StO2 | |||
| StO2 (%) | 76 [70, 81] | 70 [59, 78] | 0.07 |
| StO2 when MAP < MAPopt−5 (%) | 76 [73, 80] | 70 [58, 78] | 0.10 |
| StO2 when MAP within ± 5 MAPopt (%) | 76 [69, 83] | 71 [59, 79] | 0.11 |
| StO2 when MAP > MAPopt + 5 (%) | 77 [71, 81] | 69 [60, 78] | 0.07 |